№ lp_2_3_36904
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This dissertation explores the biogenesis, characterization, and therapeutic potential of extracellular vesicles derived from human iPSC-derived brain organoids, highlighting their application in regenerative therapies for brain damage and neurodegenerative diseases.
Year: 2024
Region / City: United States
Topic: Stem Cell Therapy, Extracellular Vesicles, Brain Organoids
Document Type: Dissertation
Institution: Department of Chemical and Biomedical Engineering
Author: Chang Liu
Advisor: Dr. Yan Li
Target Audience: Researchers in Regenerative Medicine, Neuroscience
Period of Validity: N/A
Approval Date: N/A
Modification Date: N/A
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Highlighting the Potential of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Alleviating Hypoxic-Ischemic Encephalopathy: Reshaping the Post-HI Milieu
Author: Nik Heijmink
Student number: 6706541
Date: 12/08/2024
Type of document: Writing assignment
Academic program: Neuroscience and Cognition master program, Experimental and Clinical Neuroscience track
Institution: University Medical Centre Utrecht
Department: Department for Developmental Origins of Disease, Division Woman and Baby, Brain Center
City: Utrecht
Country: The Netherlands
Daily supervision: M.J.V. Brandt, PhD
Examiner: C.H.A. Nijboer, Associate Professor
Secondary examiner: R.J. Pasterkamp, Full Professor
Main topic: Hypoxic-ischemic encephalopathy and mesenchymal stem cell-derived extracellular vesicles
Key subjects: Neuroinflammation, neurogenesis, hypothermia treatment, microglia, subventricular zone, exosomes
Supplementary Figures: Pluripotent stem cell–derived extracellular vesicles for systemic immune modulation in diabetes therapy
Year: 2026
Region / City: Los Angeles, CA, USA; Prague, Czech Republic; New Orleans, LA, USA; Birmingham, AL, USA; State College, PA, USA; Ithaca, NY, USA; Chengdu, China
Topic: Extracellular Vesicles, Stem Cells, Immune Modulation, Diabetes Therapy
Document Type: Research Supplementary Figures
Institution / Organization: University of California, Los Angeles, University of California, Los Angeles, Tulane University, University of Alabama at Birmingham, Pennsylvania State University, Cornell University, Sichuan University
Author: Jana Zarubova, Mohammad Mahdi Hasani-Sadrabadi, Yutong Wu, Graciel Diamante, Jenny Cheng, Xiao Han, Fatemeh Sadat Majedi, Li Yang, Olivia Wang, In Sook Ahn, Jianyi Zhang, Xiaojun Lance Lian, Zhen Gu, Manish J. Butte, Reza Ardehali, Peter C Butler, Tony Ye Hu, Louis-S. Bouchard, Xia Yang, Song Li
Target Audience: Researchers in stem cell biology, regenerative medicine, diabetes therapy
Period of Effect: Not specified
Approval Date: Not specified
Modification Date: Not specified
Description: Research supplementary material focusing on extracellular vesicles derived from pluripotent stem cells and their role in immune modulation for diabetes treatment, including experimental figures and lipid profiles.
Multi-omics analyses of HNF4α protein domain function during human pluripotent stem cell differentiation
Year: 2026
Region / city: Edinburgh, Scotland
Topic: Human pluripotent stem cell differentiation, protein domain function, liver differentiation
Document Type: Research Paper
Institution: Medical Research Council Centre for Regenerative Medicine, University of Edinburgh
Authors: Yu Wang, Michael H. Tatham, Wolfgang Schmidt-Heck, Carolyn Swann, Karamjit Singh-Dolt, Jose Meseguer-Ripolles, Baltasar Lucendo-Villarin, Tilo Kunath, Timothy R. Rudd, Andrew Smith, Jan G. Hengstler, Patricio Godoy, Ronald T. Hay, David C. Hay
Target Audience: Researchers, biologists, medical professionals
Effective Period: Not specified
Approval Date: Not specified
Modification Date: Not specified
Context: This research paper presents the results of using multi-omics analysis and genome editing to study the role of the HNF4α protein in liver differentiation from human pluripotent stem cells.
Highlighting the Potential of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Alleviating Hypoxic-Ischemic Encephalopathy: Reshaping the Post-HI Milieu
Author: Nik Heijmink
Student number: 6706541
Date: 12/08/2024
Type of document: Writing assignment
Academic program: Neuroscience and Cognition master program, Experimental and Clinical Neuroscience track
Institution: University Medical Centre Utrecht
Department: Department for Developmental Origins of Disease, Division Woman and Baby, Brain Center
City: Utrecht
Country: The Netherlands
Daily supervision: M.J.V. Brandt, PhD
Examiner: C.H.A. Nijboer, Associate Professor
Secondary examiner: R.J. Pasterkamp, Full Professor
Main topic: Hypoxic-ischemic encephalopathy and mesenchymal stem cell-derived extracellular vesicles
Key subjects: Neuroinflammation, neurogenesis, hypothermia treatment, microglia, subventricular zone, exosomes
Differential expression analysis of miRNAs isolated from pleural fluid extracellular vesicles using the Nanostring nCounter® miRNA expression assay
Year: 2021
Region / city: Queensland, Australia
Topic: miRNA expression analysis, pleural effusions, extracellular vesicles
Document type: Research article
Institution: The University of Queensland Thoracic Research Centre, The Prince Charles Hospital
Authors: Tian Mun Chee, Caeli J. Zahra, Kwun M. Fong, Ian A. Yang, Rayleen V. Bowman
Target audience: Researchers in molecular biology, oncology
Period of validity: N/A
Approval date: N/A
Date of changes: N/A
Supplementary Figures: Pluripotent stem cell–derived extracellular vesicles for systemic immune modulation in diabetes therapy
Year: 2026
Region / City: Los Angeles, CA, USA; Prague, Czech Republic; New Orleans, LA, USA; Birmingham, AL, USA; State College, PA, USA; Ithaca, NY, USA; Chengdu, China
Topic: Extracellular Vesicles, Stem Cells, Immune Modulation, Diabetes Therapy
Document Type: Research Supplementary Figures
Institution / Organization: University of California, Los Angeles, University of California, Los Angeles, Tulane University, University of Alabama at Birmingham, Pennsylvania State University, Cornell University, Sichuan University
Author: Jana Zarubova, Mohammad Mahdi Hasani-Sadrabadi, Yutong Wu, Graciel Diamante, Jenny Cheng, Xiao Han, Fatemeh Sadat Majedi, Li Yang, Olivia Wang, In Sook Ahn, Jianyi Zhang, Xiaojun Lance Lian, Zhen Gu, Manish J. Butte, Reza Ardehali, Peter C Butler, Tony Ye Hu, Louis-S. Bouchard, Xia Yang, Song Li
Target Audience: Researchers in stem cell biology, regenerative medicine, diabetes therapy
Period of Effect: Not specified
Approval Date: Not specified
Modification Date: Not specified
Description: Research supplementary material focusing on extracellular vesicles derived from pluripotent stem cells and their role in immune modulation for diabetes treatment, including experimental figures and lipid profiles.
Detection and physicochemical characterization of Membrane Vesicles (MVs) of Lactobacillus reuteri DSM 17938
Year: 2026
Region / city: Chieti, Italy
Topic: Microbiology, Probiotics, Nanoparticles
Document type: Research article
Author: Rossella Grande, Christian Celia, Gabriella Mincione, Annarita Stringaro, Luisa Di Marzio, Marisa Colone, Maria Carmela Di Marcantonio, Luca Savino, Valentina Puca, Roberto Santoliquido, Marcello Locatelli, Raffaella Muraro, Luanne Hall-Stoodley, Paul Stoodley
Target audience: Researchers in microbiology, probiotics, nanomedicine
Period of validity: N/A
Date of approval: N/A
Date of modifications: N/A
Topics: Cell-Derived PLURIPOTENT Vesicles