№ files_lp_4_process_3_138919
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Year: 2026
Region / city: Edinburgh, Scotland
Topic: Human pluripotent stem cell differentiation, protein domain function, liver differentiation
Document Type: Research Paper
Institution: Medical Research Council Centre for Regenerative Medicine, University of Edinburgh
Authors: Yu Wang, Michael H. Tatham, Wolfgang Schmidt-Heck, Carolyn Swann, Karamjit Singh-Dolt, Jose Meseguer-Ripolles, Baltasar Lucendo-Villarin, Tilo Kunath, Timothy R. Rudd, Andrew Smith, Jan G. Hengstler, Patricio Godoy, Ronald T. Hay, David C. Hay
Target Audience: Researchers, biologists, medical professionals
Effective Period: Not specified
Approval Date: Not specified
Modification Date: Not specified
Context: This research paper presents the results of using multi-omics analysis and genome editing to study the role of the HNF4α protein in liver differentiation from human pluripotent stem cells.
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ENGINEERING EXTRACELLULAR VESICLES OF HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED BRAIN ORGANOIDS IN STATIC AND DYNAMIC SYSTEMS
Year: 2024
Region / City: United States
Topic: Stem Cell Therapy, Extracellular Vesicles, Brain Organoids
Document Type: Dissertation
Institution: Department of Chemical and Biomedical Engineering
Author: Chang Liu
Advisor: Dr. Yan Li
Target Audience: Researchers in Regenerative Medicine, Neuroscience
Period of Validity: N/A
Approval Date: N/A
Modification Date: N/A
Supplementary Figures: Pluripotent stem cell–derived extracellular vesicles for systemic immune modulation in diabetes therapy
Year: 2026
Region / City: Los Angeles, CA, USA; Prague, Czech Republic; New Orleans, LA, USA; Birmingham, AL, USA; State College, PA, USA; Ithaca, NY, USA; Chengdu, China
Topic: Extracellular Vesicles, Stem Cells, Immune Modulation, Diabetes Therapy
Document Type: Research Supplementary Figures
Institution / Organization: University of California, Los Angeles, University of California, Los Angeles, Tulane University, University of Alabama at Birmingham, Pennsylvania State University, Cornell University, Sichuan University
Author: Jana Zarubova, Mohammad Mahdi Hasani-Sadrabadi, Yutong Wu, Graciel Diamante, Jenny Cheng, Xiao Han, Fatemeh Sadat Majedi, Li Yang, Olivia Wang, In Sook Ahn, Jianyi Zhang, Xiaojun Lance Lian, Zhen Gu, Manish J. Butte, Reza Ardehali, Peter C Butler, Tony Ye Hu, Louis-S. Bouchard, Xia Yang, Song Li
Target Audience: Researchers in stem cell biology, regenerative medicine, diabetes therapy
Period of Effect: Not specified
Approval Date: Not specified
Modification Date: Not specified
Description: Research supplementary material focusing on extracellular vesicles derived from pluripotent stem cells and their role in immune modulation for diabetes treatment, including experimental figures and lipid profiles.
Harnessing Multi-Omics Approaches to Elucidate the Role of Chinese Herbal Compounds in Chemotherapy-Induced Gastrointestinal Damage
Journal: World Journal of Gastrointestinal Oncology
Manuscript Type: Editorial
Authors: Chang Qiao; Hao-Xiang Zhang; Xiao-Tong Tian; Yan-Jing Zhang; De-Hui Li
Co-first authors: Chang Qiao; Hao-Xiang Zhang
Corresponding authors: Yan-Jing Zhang; De-Hui Li
Affiliated Institutions: Hebei University of Chinese Medicine; Guang’anmen Hospital, Academy of Chinese Medical Sciences; The First Affiliated Hospital of Hebei University of Chinese Medicine
Country: China
Region / City: Shijiazhuang, Hebei Province; Beijing
Research Field: Gastrointestinal Oncology; Integrative Medicine; Multi-omics Research
Keywords: Chinese herbal compounds; Gastrointestinal microenvironment; Chemotherapy; Multi-omics; Intestinal microecology
Funding: Government-funded Project of the Outstanding Talents Training Program in Clinical Medicine (ZF2023165); Key Research and Development Projects of Hebei Province (18277731D); Natural Science Foundation of Hebei Province (H202423105)
Received: September 16, 2024
Revised: November 11, 2024
Accepted: November 25, 2024
Published online: February 15, 2025
DOI: 10.4251/wjgo.v17.i2.101500
Article URL: https://www.wjgnet.com/1948-5204/full/v17/i2/101500.htm
Subject Focus: Mechanisms of Chinese herbal compounds in mitigating chemotherapy-induced gastrointestinal injury through multi-omics approaches
Institutions Involved: Graduate School of Hebei University of Chinese Medicine; Department of Oncology I and II, The First Affiliated Hospital of Hebei University of Chinese Medicine; Guang’anmen Hospital, Academy of Chinese Medical Sciences
Multi-omics analysis of ECM degradation and deposition in hepatocellular carcinoma
Year: 2026
Authors: Xiangting Zeng, Liang Guo, Fenglan Wang, Peng Wang, Huan Gu
Field: Oncology, Molecular Biology
Document type: Research article
Institution: Not specified
Target audience: Researchers and clinicians in oncology and molecular biology
Study focus: Impact of extracellular matrix (ECM) remodeling on hepatocellular carcinoma
Methods: Multi-omics analysis
Single Cell multi-omics for minimally invasive assessment of Treatment efficacy in WMAssessing treatment efficacy is mandatory in Waldenström’s Macroglobulinemia (WM).
Year: 2022
Region / City: Pamplona, Spain
Topic: Research on Waldenström’s Macroglobulinemia treatment efficacy
Document Type: Research Article
Institution: University of Navarra, CIMA
Author: Bruno Paiva
Target Audience: Researchers in Hematology, Medical Professionals
Period of Validity: Not specified
Approval Date: Not specified
Modification Date: Not specified
Context: Research article on using flow cytometry for minimally invasive assessment of treatment efficacy in Waldenström’s Macroglobulinemia.
Topics: HNF4 PLURIPOTENT Multi-Omics