№ lp_2_1_32490
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Medical source describing clinical characteristics, diagnostic criteria, prevalence, and treatment approaches for MOG antibody disease.
Year:
2018
Disorder Type:
Neuro-inflammatory disease
Target:
Central nervous system
Symptoms:
Optic neuritis, spinal cord inflammation, demyelination
Diagnosis:
Positive MOG antibody test, MRI evidence of demyelination
Treatment:
Immunoglobulin therapy (IVIG/SCIG), other therapies as determined by physician
Prevalence:
1 per 500,000 people
References:
Fan S et al., 2018; Kezuka T & Ishikawa H, 2018; Dos Passos GR et al., 2018; Weber MS et al., 2018
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2014
Region / city:
Bethesda, MD
Topic:
Hematology, Immunohematology, Laboratory Procedures
Document Type:
Procedure Manual
Organization / Institution:
American Association of Blood Banks
Author:
Roback JD
Target Audience:
Laboratory personnel, medical professionals
Period of validity:
Ongoing, as of revision date
Approval Date:
March 1, 2014
Date of Changes:
March 1, 2014
References:
AABB Technical Manual, 17th ed., Methods in Immunhematology 3rd ed., Standards for Hospital Transfusion Services Version 3
Scope:
The document provides instructions for the removal of antibodies from coated red blood cells using freeze-thaw elution techniques, specifically for investigating ABO hemolytic disease of the fetus and newborn.
Year:
N/A
Region / City:
N/A
Topic:
Quality Control, Blood Grouping, Antibody Screening
Document Type:
Standard Operating Procedure
Organization / Institution:
N/A
Author:
N/A
Target Audience:
Laboratory personnel involved in blood grouping and antibody screening
Period of validity:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Journal:
World Journal of Gastrointestinal Pathophysiology
Manuscript Type:
Original Article
Study Design:
Retrospective Cohort Study
Authors:
Hyun Ah Chung; Sun-Young Lee; Hee Won Moon; Jeong Hwan Kim; In-Kyung Sung; Hyung Seok Park; Chan Sup Shim; Hye Seung Han
Affiliations:
Department of Internal Medicine, Department of Laboratory Medicine, and Department of Pathology, Konkuk University School of Medicine, Seoul 05030, South Korea
Corresponding Author:
Sun-Young Lee, MD, PhD
Country:
South Korea
Funding:
Supported by Konkuk University in 2015 (No. KU2015-A019-0270)
Institutional Review Board Approval:
Konkuk University School of Medicine (KUH1010625)
Clinical Trial Registration:
ClinicalTrials.gov ID: KCT0001302
Received:
December 27, 2015
Accepted:
July 11, 2016
Publication Year:
2016
Keywords:
Antibody; Helicobacter pylori; Hepatitis B; Immunoglobulin G; Pepsinogen
License:
Creative Commons Attribution Non Commercial (CC BY-NC 4.0)
Year:
2023
Region / City:
Not specified
Topic:
Anti-nuclear antibody testing, technical issues
Document type:
Update
Author:
Dr. Anna McHugh
Target audience:
Healthcare professionals
Action period:
May 2023
Approval date:
Not specified
Change date:
16th May 2023
Context:
The document is an update on delays and technical issues with anti-nuclear antibody testing, outlining the steps being taken to resolve the situation and advising healthcare professionals on necessary actions for patients.
Year:
2024
Region / city:
Hull, United Kingdom
Topic:
Coeliac Disease Screening
Document Type:
Medical Guidelines
Organization:
NHS
Author:
Anna McHugh
Target Audience:
Healthcare Professionals
Period of Validity:
From January 2023
Approval Date:
Not specified
Date of Changes:
February 2024
Year:
2023
Region / City:
Not specified
Topic:
Monoclonal antibody sequences, growth rate inhibition in cell models
Document type:
Research Supplementary Material
Organization / Institution:
Not specified
Author:
Not specified
Target audience:
Researchers, biomedical professionals
Effective period:
Not specified
Approval date:
Not specified
Modification date:
Not specified
Year:
2012
Region / City:
United Kingdom
Subject:
Blood Grouping, Red Cell Antibody Testing, Pregnancy
Document Type:
Audit Tool
Institution:
British Committee for Standards in Haematology (BCSH)
Author:
N/A
Target Audience:
Healthcare professionals involved in blood transfusion, obstetrics, and fetal medicine
Period of Application:
Ongoing
Date of Approval:
N/A
Date of Changes:
N/A
Year:
2021
Region / city:
Various locations in the United States
Topic:
COVID-19 Treatment
Document type:
Clinical Trial Report
Institution:
Regeneron Pharmaceuticals, NIAID/CoVPN
Author:
Multiple investigators and research teams
Target audience:
Healthcare professionals, researchers, clinical trial coordinators
Period of validity:
Study conducted during 2020-2021
Approval date:
Not specified
Date of changes:
Not specified
Year:
2026
Region / City:
Canada, multiple cities
Subject:
COVID-19 treatment eligibility
Document Type:
Medical referral form
Organization / Institution:
Health Canada; regional hospitals
Author:
Clinicians completing referral
Target Audience:
Healthcare providers and eligible patients
Eligibility Criteria:
Adults and pediatric patients ≥12 years, ≥40 kg, at high risk of severe COVID-19
Treatment Window:
Within 7 days of symptom onset
Authorization:
Interim authorization (Interim Order) by Health Canada
Patient Data Fields:
Name, Date of birth, Allergies, Address, Contact information, Health Card Number
Clinical Criteria:
Symptomatic status, vaccination status, comorbidities, immunosuppression, prior COVID-19 infection
Referral Confirmation:
Clinician attestation with signature, date, and College number
Year:
2023
Region / city:
Rockville, MD, United States; Ottawa, ON, Canada
Topic:
NMR assignments, antibody research, protein expression
Document type:
Research article
Institution:
Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology, University of Maryland; Centre for Oncology, Radiopharmaceuticals and Research, Biologics and Radiotherapeutic Drugs Directorate, Health Canada
Author:
Tsega L. Solomon, Kinlin Chao, Genevieve Gingras, Yves Aubin, William B. O’Dell, John P. Marino, Robert G. Brinson
Target audience:
Researchers in biochemistry, protein chemistry, pharmaceutical sciences
Effective period:
2023 and onwards
Approval date:
N/A
Date of changes:
N/A
Keywords:
backbone assignments, Fab domain, NISTmAb, biologics, monoclonal antibodies
Context description:
This document presents the results of a study on the backbone NMR assignments of the yeast-expressed Fab fragment of the NISTmAb antibody, aimed at advancing structural characterization techniques for monoclonal antibodies.
Instrument:
Immucor Galileo Echo
Test Panels:
Capture-R Ready-ID; Capture-R Extend I; Capture-R Extend II
Test Method:
IgG antibody panel using Capture-R technology
Temperature:
37°C
Specimen Type:
EDTA anticoagulated whole blood; serum from fully clotted blood
Specimen Stability:
≤5 days from collection; ≤4 days for recently transfused or pregnant patients
Exclusion Criteria:
Hemolyzed (≥3+), lipemic, or icteric samples not accepted
Reagents:
Capture LISS; Capture-R Ready-ID; Capture-R Extend I & Extend II; Capture-R Indicator Cells; WB corQC; PHIX buffered saline
Equipment:
Immucor Galileo Echo
Quality Control:
Commercial WB corQC performed daily; 24-hour control interval after validation
Controls:
Positive and negative controls included in each 14-cell panel
Related Policy:
SWIM manual NRT.007 “Antibody Identification of Warm Reactive Antibodies”
Reporting:
Results reviewed and confirmed by technologist; specimens forwarded for additional antibody testing if required
Restrictions:
Partially used strips cannot be reused
References:
Galileo Echo Operator Manual; SWIM manual
Year:
2022
Region / City:
Belfast
Subject:
COVID-19, SARS-CoV-2, antibody neutralisation
Document type:
Research study call
Organization / Institution:
Queen’s University Belfast
Author:
Ultan Power
Target audience:
Healthy volunteers aged 18-65
Study period:
Ongoing
Approval date:
Not specified
Modification date:
Not specified
Year:
2023
Region / city:
Not specified
Topic:
Recombinant proteins, antibodies, and reagents for macrophage polarization and related techniques
Document type:
Laboratory protocol
Institution:
Not specified
Author:
Not specified
Target audience:
Researchers in molecular biology and immunology
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
N/A
Region / city:
N/A
Topic:
irMG clinical manifestations and treatment outcomes
Document Type:
Clinical data table
Institution / Organization:
N/A
Author:
N/A
Target Audience:
Medical professionals, researchers
Period of validity:
N/A
Approval date:
N/A
Date of changes:
N/A
Note:
Contextual description