Year:
2023
Region / city:
Rockville, MD, United States; Ottawa, ON, Canada
Topic:
NMR assignments, antibody research, protein expression
Document type:
Research article
Institution:
Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology, University of Maryland; Centre for Oncology, Radiopharmaceuticals and Research, Biologics and Radiotherapeutic Drugs Directorate, Health Canada
Author:
Tsega L. Solomon, Kinlin Chao, Genevieve Gingras, Yves Aubin, William B. O’Dell, John P. Marino, Robert G. Brinson
Target audience:
Researchers in biochemistry, protein chemistry, pharmaceutical sciences
Effective period:
2023 and onwards
Approval date:
N/A
Date of changes:
N/A
Keywords:
backbone assignments, Fab domain, NISTmAb, biologics, monoclonal antibodies
Context description:
This document presents the results of a study on the backbone NMR assignments of the yeast-expressed Fab fragment of the NISTmAb antibody, aimed at advancing structural characterization techniques for monoclonal antibodies.
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