№ lp_1_2_44389
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PhD research project focused on biosynthesis of natural products, enzyme engineering, and synthetic biology for drug development, with an emphasis on microbial genomics and genetic manipulation.
Year:
N/A
Region / City:
N/A
Theme:
Enzyme engineering & Synthetic biology
Document Type:
PhD Research Project
Organization / Institution:
SBS (School of Biological Sciences), NTU
Author:
Liang Zhao-Xun
Target Audience:
PhD candidates in biological sciences
Period of Action:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Note:
Context
Price: 8 / 10 USD
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Subject:
Plant immunity and defense signaling
Scientific Field:
Plant molecular biology
Research Focus:
N-hydroxy pipecolic acid biosynthesis and regulation of defense responses
Organisms Studied:
Arabidopsis thaliana; Solanum lycopersicum (tomato)
Molecular Pathways:
NHP biosynthetic pathway; salicylic acid–related defense pathways
Genes and Proteins:
NAC90, NAC61, NAC36, ALD1, SARD4, FMO1, ICS1, CAMTA3
Experimental Methods:
Label-free proteomics; qRT-PCR; chromatin immunoprecipitation sequencing; chromatin immunoprecipitation-qPCR; dual luciferase promoter activity assays; metabolite analysis by Xevo TQ-S micro Triple Quadrupole Mass Spectrometry
Experimental Material:
Wild-type plants; overexpression lines; gene knockout mutants
Measured Parameters:
Metabolite abundance; transcript levels; protein accumulation; plant growth phenotypes
Biological Replicates:
Three independent biological replicates for molecular assays; eighteen plants per genotype for phenotypic measurements
Statistical Analysis:
Student’s t test; ANOVA
Data Type:
Supplementary figure descriptions and experimental annotations
Type of Document:
Scientific supplementary material
Associated Data:
Proteomics datasets; transcriptome comparisons; metabolite quantification; phylogenetic analysis of NAC transcription factors
Year:
2026
Region / City:
United Kingdom
Topic:
Procurement, Environmental Restoration
Document Type:
Request for Quotation
Organization:
Natural England
Author:
Not specified
Target Audience:
Potential suppliers for environmental projects
Period of Action:
From 16/02/2026 to 31/03/2026
Approval Date:
Not specified
Amendment Date:
Not specified
Context:
This is a Request for Quotation (RFQ) issued by Natural England to potential suppliers for the development of a KPI framework to measure the environmental restoration efforts in Sherwood Forest and Mercia Mudwoods.
Year:
2024
Region / city:
Bristol
Topic:
Employment Application
Document Type:
Job Application Form
Organization:
Avon Wildlife Trust
Author:
Avon Wildlife Trust
Target Audience:
Job Applicants
Period of validity:
Until 17th March 2024
Date of Approval:
N/A
Date of Changes:
N/A
Year:
2017
Region / city:
Bonn, Germany
Topic:
Biodiversity and Ecosystem Services
Document type:
Report
Organization:
Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES)
Author:
IPBES Secretariat
Target audience:
Experts in biodiversity and ecosystem services, policymakers
Period of validity:
2014–2018
Approval date:
7 February 2017
Modification date:
Not specified
Year:
2021
Region / city:
USA
Topic:
Reprogramming Process for Defense Funds
Document Type:
Internal Process Guide
Agency / Institution:
Air Force Life Cycle Management Center (AFLCMC)
Author:
AFLCMC/FZA
Target Audience:
Financial Managers, Program Offices, Directorate Staff
Effective Date:
15 Apr 2021
Date of Changes:
9 Sep 2012, 3 Jul 2014, 30 Sep 2014, 9 Feb 2016, 17 Oct 2018, 15 Apr 2021
Scope:
Reprogramming of Defense Funds for Program Requirements
Period of Validity:
Ongoing
Approval Date:
15 Apr 2021
Context:
A guideline for financial analysts on the process and documentation required for reprogramming funds within the Department of Defense, including Below and Above Threshold Reprogramming actions.
Process Owner:
AFLCMC/FZA
Date:
10 July 2023
Version:
3.2
Type:
Internal Process Guide
Scope:
Reprogramming of investment funds within DoD programs
Audience:
Program Financial Analysts, PEO CFOs, Directorate staff
Attachments:
BTR Request Form (Attachment 1), Reprogramming Requirements Summary (Attachment 2)
Applicable Legislation:
DoD Appropriations Acts, Congressional Guidance
Update History:
Version 1.0 (9 Sep 2012), 1.1 (30 Sep 2014), 2.0 (9 Feb 2016), 2.1 (17 Oct 2018), 3.0 (7 Apr 2021), 3.1 (9 Jun 2022), 3.2 (10 Jul 2023)
Year:
2024
Region / city:
United States
Subject:
Defense, Budget, Reprogramming, Congress
Document Type:
Government policy document
Agency:
Department of Defense
Author:
Not specified
Target audience:
Congressional committees, Department of Defense officials
Period of validity:
Fiscal Year 2024
Approval date:
Not specified
Date of changes:
Not specified
Note:
Context
Year:
2023
Region / City:
Queenstown, New Zealand
Topic:
Immune therapies, cancer treatment, cell and gene therapy
Document Type:
Event Description
Organization / Institution:
International Society for Cell and Gene Therapy (ISCT), Liger Leadership Academy
Authors:
Emily Blyth, Alicia Didsbury
Target Audience:
Researchers, medical professionals, general public interested in immune therapies
Date of Approval:
August 5, 2023
Date of Changes:
N/A
Document type:
Scientific research article
Research field:
Stem cell biology and regenerative medicine
Main topic:
Molecular mechanisms of somatic cell reprogramming
Key molecule:
SMAD6
Signaling pathway:
TGF-β/BMP signaling pathway
Biological process:
Oocyte extract–induced cellular reprogramming
Cells studied:
Human skin fibroblasts (HSFs)
Induced cell type:
Induced multipotent stem cells (IMS)
Key pluripotency markers:
OCT4, NANOG
Experimental approach:
Transcriptomic analysis and functional validation
Materials used:
Fish oocyte extract, human skin fibroblasts
Cell culture conditions:
DMEM/F12 medium with 10% fetal bovine serum, 37°C, 5% CO₂
Author:
Wei-Wen Fan; He-Ling Yuan; Ying Zhang; Xi-Long Zhao; Qiang Wang; Xue-Feng Bai; Xing-Hua Pan; Xiang-Qing Zhu
Author contribution note:
Wei-Wen Fan, He-Ling Yuan, and Ying Zhang contributed equally
Correspondence:
Xiang-Qing Zhu; Xing-Hua Pan
Institution:
The Basic Medical Laboratory of the 920th Hospital of Joint Logistics Support Force of PLA
Laboratories:
The Transfer Medicine Key Laboratory of Cell Therapy Technology of Yunnan Province; The Integrated Engineering Research Center of Cell Biological Medicine of State and Regions
City:
Kunming
Province:
Yunnan Province
Country:
China
Research objective:
Investigation of gene expression dynamics and signaling regulation during fish oocyte extract–induced reprogramming of human somatic cells