№ files_lp_4_process_3_071004
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Research article analyzing the relationship between survey response burden and response rates across 68 survey waves, quantifying the influence of respondent commitment and monetary incentives.
Year:
2004–2009
Location:
Switzerland, including Cantons Zürich, Ticino, Basel, Bern
Subject:
Survey Methodology, Response Behavior, Transport Studies
Document Type:
Research Article
Institution:
Institute for Transport Planning and Systems (IVT), ETH Zürich
Authors:
Basil Schmid, Kay W. Axhausen
Target Audience:
Academics, Market Researchers
Sample Size:
50–9,330 respondents per survey wave
Survey Type:
Self-administered surveys, Stated Preference (SP), Stated Response (SR)
Response Measurement:
Response Burden Scores, Response Rates, Cooperation Rates
Data Collection:
Mailback surveys, Pre-tests, Monetary Incentives
Analysis:
Comparison of all respondents versus pre-recruited respondents, Quantitative modeling of response rates
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Test SensitivityTP/TP+FN SpecificityTN/FP+TN PPVTP/TP+FP NPVTN/TN+FN Limitations USC pathway1 80.4% 47.2% 3.5% 99.0% low no’s of confirmed CRCAUC=0.65 Raman-CRC blood test* 85.7% 68% 14% 98.7:
//doi.org/10.1111/apt.13846
2. Lung PF, Burling D, Kallarackel L, et al. Implementation of a new CT colonography service:
5 year experience. Clin Radiol. 2014; 69(6): 597-605. doi: 10.1016/j.crad.2014.01.007.3. Bowles CJ, Leicester R, Romaya C, et al. A prospective study of colonoscopy practice in the UK today: are we adequately prepared for national colorectal cancer screening tomorrow? Gut 2004; 53: 277-283.1) Can you describe the current colorectal cancer USC referral pathway?What are your perceptions of it? (Prompt: memorised or need to refer to it, makes secondary care the gatekeeper for tests, NICE criteria, timeliness, capacity, reassurance to have a guideline to follow, ignores GP’s ‘instinct’)2) Experience of the timeframe from referral to colonoscopy/CTC? How do you manage patient’s expectation? Frequency of repeat consultations between referral and test being done?(Prompt: 37 days average)3) Do you consider your personal volume of USC pathway referrals to be just right, too few, or too many?(Prompt: how much does knowledge of waiting times and resource capacity affect your likelihood to refer a patient? 4). If resources weren’t a problem and if you could wave a magic wand tomorrow what do you think we should do about improving outcomes from CRC? What do you perceive are the barriers to early diagnosis of CRC?(Prompt: Wales is 22nd of 28 in the European league table of CRC survival, screening problems, resources, effective tests, patient choice, patient education). Perception of need for better access to diagnostics in primary care (invasive and non-invasive)5). Which situation would the Raman-CRC blood test be of most value to a GP:-non-specific symptoms? eg constipation, abdominal pain -younger age group below USC age? -all USC patients? What would a USC pathway look like with Raman-CRC embedded? -should it be a secondary care tool ie decision to perform colonoscopy or not: help with triage/prioritisation of referral in secondary care6). Given the Raman-CRC test performance described (on vignette sheet) would you have confidence to use it? If not, what sens/spec/PPV/NPV would it need to have?(Prompt: to seek to understand what is most important for a GP, ability to exclude (NPV) or to correctly identify cancer (PPV))7).What additional clinical trials would you like to see with the blood test before implementation?Further observational work with larger numbers/centres/situations?Release test for use and observe outcomes? RCT test v no test?Comparison with FIT?NICE guidance?1) Can you describe the current colorectal cancer USC referral pathway?What are your perceptions of it? (Prompt: memorised or need to refer to it, makes secondary care the gatekeeper for tests, NICE criteria, timeliness, capacity, reassurance to have a guideline to follow, ignores GP’s ‘instinct’)2) Experience of the timeframe from referral to colonoscopy/CTC? How do you manage patient’s expectation? Frequency of repeat consultations between referral and test being done?(Prompt: 37 days average)3) Do you consider your personal volume of USC pathway referrals to be just right, too few, or too many?(Prompt: how much does knowledge of waiting times and resource capacity affect your likelihood to refer a patient? 4). If resources weren’t a problem and if you could wave a magic wand tomorrow what do you think we should do about improving outcomes from CRC? What do you perceive are the barriers to early diagnosis of CRC?(Prompt: Wales is 22nd of 28 in the European league table of CRC survival, screening problems, resources, effective tests, patient choice, patient education). Perception of need for better access to diagnostics in primary care (invasive and non-invasive)5). Which situation would the Raman-CRC blood test be of most value to a GP:-non-specific symptoms? eg constipation, abdominal pain -younger age group below USC age? -all USC patients? What would a USC pathway look like with Raman-CRC embedded? -should it be a secondary care tool ie decision to perform colonoscopy or not: help with triage/prioritisation of referral in secondary care6). Given the Raman-CRC test performance described (on vignette sheet) would you have confidence to use it? If not, what sens/spec/PPV/NPV would it need to have?(Prompt: to seek to understand what is most important for a GP, ability to exclude (NPV) or to correctly identify cancer (PPV))7).What additional clinical trials would you like to see with the blood test before implementation?Further observational work with larger numbers/centres/situations?Release test for use and observe outcomes? RCT test v no test?Comparison with FIT?NICE guidance?Box S1. GP focus group questions.VIGNETTESAssumptions: Colonoscopy/CTC capacity is the same as present Raman-CRC blood test is routinely available under local guidelines.Raman-CRC test performance is 85.7% sensitivity, 68% specificity, 14% PPV, 98.7% NPV, based on interim analysis of 120 cases and controls.1. 60 y.o. male presents with tiredness. His wife (also in the practice) diagnosed with breast cancer a year ago and just completing adjuvant chemotherapy. He has had time off work himself when she has been ill with side effects. On deeper questioning he describes 6 weeks of increased stool frequency (usually once/day, now 3 times per day). No history of rectal bleeding or mucous, abdominal pain or weight loss. Doesn’t smoke. Abdominal and rectal examinations are normal. Simple diagnostics show he is not anaemic and a stool culture is negative.a) Refer to secondary care on USC pathway without further testingb) Request Raman-CRC blood test to risk stratifyc) Involve patient in decision making? Explore patient expectations/underlying concerns....d) Other?2. A 50 year old patient who is a frequent attender describes three or four episodes of rectal bleeding. This is fresh blood, noticed in the toilet water. No anal pain or itching. No change on bowel habit. Appetite and weight stable. On citalopram for anxiety. No relevant family history. Abdominal examination: appendicectomy scar, nil else. Rectal exam: small skin tags, no masses felt, no blood on glove, no proctoscope available. FBC normal. Action?3. 45 year old female patient, complains of tiredness and self limiting looser stools for 3 weeks, but does have a FH of bowel cancer. Examination normal.Decision made to perform a Raman-CRC blood test. The test returns positive 2 days later. How would you go about discussing this with the patient in the fol
Year:
2024
Region / City:
Hyderabad, Telangana
Subject:
Commercial Taxes, Public Services
Document Type:
Official Notice
Organization:
Government of Telangana, Commercial Taxes Department
Author:
Joint Commissioner (ST), Hyderabad Rural Division
Target Audience:
Government Officials, Candidates in Commercial Tax Department
Period of Action:
Ongoing
Approval Date:
27-05-2024
Amendment Date:
N/A
Year:
2020
Region / City:
Bowdoinham, Maine
Subject:
Development, Urban Planning
Document Type:
Research Paper
Organization / Institution:
Bowdoinham Town Government
Author:
Rodger Heidgerken
Target Audience:
Local Government Officials, Urban Planners
Period of Validity:
2011-2024
Approval Date:
N/A
Modification Date:
N/A
Note:
Year
Author:
Andreas Fønss Møller, Kedar Nath Natarajan
Year:
2026
Region / City:
N/A
Topic:
Astronomy
Document Type:
Educational Material
Organization / Institution:
N/A
Author:
N/A
Target Audience:
Students, Educators
Period of Action:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Year:
2023
Region / City:
Wuhan, China
Topic:
Immunology, Cancer Research, Gene Expression, Immunotherapy
Document Type:
Research Article
Institution:
Wuhan University of Science & Technology, Huazhong University of Science and Technology, Anhui Normal University
Authors:
Fei-Fei Hu, Chun-Jie Liu, Lan-Lan Liu, Qiong Zhang, An-Yuan Guo
Target Audience:
Researchers, Healthcare Professionals, Academics in Immunology and Oncology
Period of Validity:
N/A
Approval Date:
N/A
Date of Last Revision:
N/A
Year:
2023
Region / City:
N/A
Topic:
Drug repurposing, machine learning models
Document Type:
Research article
Organization / Institution:
N/A
Author:
N/A
Target Audience:
Researchers, Data Scientists
Effective Period:
N/A
Approval Date:
N/A
Modification Date:
N/A
Description of Document:
A research article comparing the performance of different machine learning models in predicting drug-disease approval likelihood using various optimization techniques and cross-validation methods.
Year:
2026
Region / City:
Global
Topic:
Supply chain, Data analytics, Machine learning, Risk prediction
Document type:
Research paper
Organization:
OEM
Author:
Unknown
Target audience:
Researchers, supply chain professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
2022
Region / City:
Mafraq, Jordan
Subject:
Atmospheric Science / Meteorology
Document Type:
Laboratory Experiment Report
Institution:
Meteorology Department / Mafraq Station
Author:
Not specified
Target Audience:
Students and researchers in meteorology
Observation Date:
24 March 2022
Station Identifier:
OJMF (WMO 40265)
Latitude:
32.37
Longitude:
36.25
Elevation:
687 m
Measured Variables:
Pressure, Temperature, Dew Point, Mixing Ratio, Saturation Mixing Ratio, Relative Humidity
Procedure Reference:
Skew-T/log-P thermodynamic diagram method
Data Table Included:
Yes
Year:
Not specified
Region / city:
Not specified
Theme:
Chemistry, Chemical Reactions
Document type:
Educational Material
Author:
Not specified
Target audience:
Students, Chemistry learners
Period of validity:
Not specified
Approval date:
Not specified
Modification date:
Not specified
Context:
A chemistry guide explaining the rules for predicting products in various types of chemical reactions.
Year:
2023
Region / City:
Not specified
Subject:
Linguistic Features, Eye Movement
Document Type:
Research Supplement
Organization / Institution:
Not specified
Author:
Shingo Nahatame
Target Audience:
Researchers in linguistics and psycholinguistics
Period of Validity:
Not specified
Date of Approval:
Not specified
Date of Changes:
Not specified
Year:
2022
Field:
Vascular Surgery; Rehabilitation Medicine
Topic:
Prosthetic Mobility and Functional Outcomes After Major Lower Limb Amputation
Document Type:
Scientific Research Article
Manuscript Category:
Original Article
Authors:
Arsalan Wafi; Luis Ribeiro; Vijay Kolli; Bilal Azhar; James Budge; Ian M. Loftus; Peter J. E. Holt
Institutions:
St George’s Vascular Institute, St George’s University Hospital, London, United Kingdom; Douglas Bader Rehabilitation Unit, Queen Mary’s Hospital, London, United Kingdom
Study Design:
Retrospective Cohort Study of a Prospectively Maintained Database
Study Period:
2007–2020
Follow-up End Date:
April 2021
Population:
Patients with unilateral major lower limb amputation due to advanced ischaemia or diabetic foot disease
Sample Size:
771 Patients
Clinical Conditions Studied:
Acute Limb Ischaemia; Chronic Limb-Threatening Ischaemia; Peripheral Arterial Disease; Diabetic Foot Disease
Outcome Measure:
Independent Prosthetic Mobility After Rehabilitation
Secondary Outcome:
Association Between Prosthetic Mobility and Long-Term Survival
Presentation Event:
Veith Symposium, New York, 2022
Keywords:
Amputation; Prosthetic Mobility; Rehabilitation; Functional Outcome; Survival; Gender Differences
Conflicts of Interest:
None
Year:
2023
Region / City:
Padova, Italy
Topic:
Pharmaceutical Development, Drug Solubility
Document Type:
Research Study
Organization / Institution:
University of Padova, GlaxoSmithKline
Author:
Marco Brendolan, Francesca Cenci, Konstantinos Stamatopoulos, Fabrizio Bezzo, Pierantonio Facco
Target Audience:
Pharmaceutical Researchers, Bioengineers
Period of Validity:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Year:
2020-2021
Region / Institution:
University of York, UK; Human Connectome Project (HCP), USA
Subjects:
Healthy adults, right-handed, native English speakers
Methodology:
MRI acquisition, fMRI tasks (auditory and visual), image preprocessing
Data Type:
Structural and functional neuroimaging
Authors:
Xiuyi Wang, Katya Krieger-Redwood, Meichao Zhang, Zaixu Cui, Xiaokang Wang, Theodoros Karapanagiotidis, Yi Du, Robert Leech, Boris Bernhardt, Daniel Margulies, Jonathan Smallwood, Elizabeth Jefferies
Ethics Approval:
York Neuroimaging Centre and Department of Psychology ethics committees
Tasks:
Auditory story, math, visual language, math, spatial judgments
Scanner:
Siemens 3T (Connectome and Prisma)
Processing Pipelines:
HCP minimal preprocessing, fMRIPrep 20.2.1, FreeSurfer, ANTs, FSL
Data Exclusion:
Incomplete sessions, low accuracy participants
Endnote:
Multimodal surface matching, spatial normalization to MNI templates
Year:
2012–2022
Region / City:
Kolkata, India
Country:
India
Field:
Oncology; Gastrointestinal Pathology
Topic:
Prognostic significance of tumor size and staging in ampullary adenocarcinoma
Document Type:
Scientific research article
Institution:
Tata Medical Center, Kolkata; Vanderbilt University Medical Center, Tennessee
Authors:
Paromita Roy; Pritam Ray; Rohit Tapadia; Sudeep Banerjee; Indranil Mallick; Deyali Chatterjee
Corresponding Author:
Paromita Roy
Affiliation of Corresponding Author:
Department of Pathology, Tata Medical Center, Kolkata, India
Study Design:
Retrospective clinicopathologic study
Study Population:
Patients with ampullary adenocarcinoma who underwent surgery with curative intent
Study Period:
June 2012 – June 2022
Number of Cases Analyzed:
146
Medical Procedure Context:
Whipple resection specimen evaluation
Key Variables:
Tumor size; AJCC TNM staging; disease-free survival; overall survival; perineural invasion; surgical margin status; nodal status
Ethics Approval:
Institutional review board consent waiver (EC/WV/TMC/18/23)
Keywords:
Ampulla; tumour size; survival; Whipple; AJCC; TNM; periampullary pathology
Year:
2025
Region / City:
Saitama, Japan
Topic:
Neurosurgery, Moyamoya Disease, Revascularization
Document Type:
Research Article
Organization / Institution:
Saitama Medical University International Medical Center
Author:
Koki Onodera, Akio Teranishi, Yushiro Take, Omar F. Jbarah, Hiroki Kurita
Target Audience:
Medical professionals, researchers, healthcare institutions
Period of Action:
April 2021 - March 2025
Date of Approval:
2025
Date of Changes:
N/A
Year:
2026
Region / City:
Delmarva Peninsula
Topic:
Agricultural Losses, Extreme Weather, Machine Learning
Document Type:
Research Paper
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Researchers, Agricultural Experts, Climate Scientists
Period of Validity:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified
Year:
2023
Region / City:
Elmwood
Theme:
Social-Emotional Learning, Special Education
Document Type:
Case Study
Institution:
Elmwood Elementary School
Author:
School Staff
Target Audience:
Educators, School Counselors, Special Education Professionals
Period of Action:
2023-2024 Academic Year
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2024
Note:
Region / city
Theme:
Physics, Waves, Sound, Light
Document type:
Educational booklet
Organization:
thephysicsteacher.ie
Author:
Noel Cunningham
Target audience:
Students
Period of validity:
2002-2023
Date of modifications:
04/08/2024
Document type:
Application guidance document
Subject area:
Particle astrophysics; gravitational waves
Funding body:
Science and Technology Facilities Council
Programme:
Particle Astrophysics Grants
Related collaboration:
LIGO Scientific Collaboration
Intended use:
Research grant application preparation
Structure:
Vision and approach overview with thematic sections
Scope:
Scientific themes, resource requests, and Advanced LIGO operations
Target audience:
Research institutions and grant applicants
Page limits:
Five pages for overview; two pages per FTE for each theme
Timeframe referenced:
Since April 2020; since 1 October 2021
Application components:
Vision, approach, themes, resources, governance, work plans, references