№ lp_2_1_16982
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The document is a collection of clinical studies and trials related to inflammatory bowel disease, summarizing findings from various treatment approaches and medications used in Crohn’s disease and ulcerative colitis.
Year:
2010
Region / City:
Global
Document Type:
Medical Research Article
Organization / Institution:
Various Medical Institutions and Study Groups
Author:
Colombel JF, Sandborn WJ, Reinisch W, Mantzaris GJ, Kornbluth A, et al.
Target Audience:
Healthcare professionals, researchers
Period of Action:
2006-2012
Approval Date:
April 15, 2010
Modification Date:
N/A
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Year:
2021
Region / City:
Pirassununga, SP, Brazil
Topic:
Veterinary medicine, animal welfare, swine castration
Document Type:
Research article
Institution:
University of Sao Paulo, North Carolina State University, Washington State University, Michigan State University, Iowa State University, University of Missouri
Author:
Laya Kannan Silva Alves, Monique Danielle Pairis-Garcia, Juliana Bonin Ferreira, Victoria Rocha Merenda, Rubia Mitalli Tomacheski, Pedro Henrique Esteves Trindade, Christopher Siepker, Magdiel Lopez-Soriano
Target Audience:
Researchers, veterinary professionals
Period of Study:
Not specified
Approval Date:
Not specified
Date of Revision:
Not specified
Year:
2019
Region / City:
Naas General Hospital
Topic:
Inflammatory Bowel Disease, Biologic Medication
Document Type:
Policy
Author:
Joanna Rea, Inflammatory Bowel Disease Clinical Nurse Specialist
Target Audience:
IBD CNSp, Gastroenterology team, nursing staff administering biologic medication
Approval Date:
14th January 2020
Revision Date:
January 2023
Version Number:
1
Supporting Evidence:
Infliximab, Remicade, Vedolizumab, Adalimumab, Imraldi, Amgevita, Hulio, Golimumab, Ustekinumab
Purpose:
Standardization of pre-screening and management of IBD patients requiring biologic treatment
Scope:
Biologic screening, patient education, IBD CNSp, gastroenterology team, nursing staff
Objective(s):
Ensure best practice for IBD patients on biologics
Outcome(s):
Clarity for staff on safe and evidence-based care for IBD patients on biologics
Governance:
IBD Working Group
Review Group:
Not Applicable
Date of Approval:
14th January 2020
Date of Next Revision:
January 2023
Year:
2015
Region / City:
Zurich, Switzerland
Topic:
Inflammatory bowel disease
Document type:
Journal Article
Organization / Institution:
University Hospital Zurich, University of California Riverside
Author:
Marianne R Spalinger, Declan F McCole, Gerhard Rogler, Michael Scharl
Target audience:
Researchers, medical professionals
Period of validity:
N/A
Approval date:
N/A
Modification date:
N/A
Note:
Year
Region / City:
Shanghai, China
Topic:
Tumor Immunology, Hepatocarcinogenesis
Document Type:
Research Supplementary Material
Institution:
Third Affiliated Hospital of Second Military Medical University, National Center for Liver Cancer
Author:
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei
Target Audience:
Researchers in Tumor Immunology, Oncology
Context:
A research document providing detailed methods and experimental procedures on hepatocarcinogenesis and tumor immunology based on single-cell analysis and cell culture experiments.
Year:
2025
Month of Revision:
February 2025
Country:
United Kingdom
Healthcare System:
NHS
Service:
Rheumatology Early Inflammatory Arthritis (EIA) Service
Type of Document:
Medical referral form
Target Group:
Patients aged 18 years or above
Referral Priority:
Urgent (3 week wait)
Required Referral Method:
e-RS
Clinical Criteria:
Persistent joint inflammation ≥ 6 weeks in 2 or more joints with specified clinical features
Required Investigations:
FBC, E&C, LFT, ESR, CRP, RhF, ANA, Anti-CCP, X-rays hands/feet if symptomatic
Treatment Pathway Reference:
DMARD therapy within 6 weeks if diagnosis confirmed
Follow-up Sites:
WRH, KTC, ALX
Title of study:
Addressing unmet needs in adult inflammatory bowel disease care
Type of document:
Participant Information Sheet
Study type:
Online survey as part of a Doctor of Philosophy (PhD) Degree
Researcher:
Charlotte Playford
Supervisors:
Stephanie Armstrong; Zahid Asghar; Richard Ngomba; Andrew Rochford
Institution:
University of Lincoln
Collaborating organisation:
National Institute for Health Research (NIHR) Applied Research Collaboration (ARC) East Midlands
Country:
United Kingdom
Target participants:
Healthcare clinicians working within an IBD service in the United Kingdom
Sample size:
Approximately 10 participants
Data collection method:
Online survey and optional follow-up semi-structured interview
Data storage:
University OneDrive and secure university premises
Ethical approval reference:
2024_17184
Funder:
University of Lincoln; NIHR Applied Research Collaboration (ARC) East Midlands
Purpose:
Exploration of clinician perspectives on unmet needs and multidisciplinary care in adult IBD management
Confidentiality:
Anonymous data collection with optional identifiable follow-up consent
Withdrawal policy:
Withdrawal permitted before survey submission
Year:
2024
Region / City:
Rize, Türkiye
Topic:
Geriatric sarcopenia and inflammation
Document Type:
Research article
Institution:
Recep Tayyip Erdoğan University Faculty of Medicine
Authors:
Handan Duman, Damla Tüfekçi
Target Population:
Adults aged ≥80 years
Study Design:
Cross-sectional observational study
Ethics Approval:
Recep Tayyip Erdoğan University Clinical Research Ethics Committee, decision no. 2024/175
Corresponding Author:
Handan Duman, Department of Family Medicine, Recep Tayyip Erdoğan University
Keywords:
Sarcopenia, systemic immune-inflammation index (SII), C-reactive protein/albumin ratio (CAR), very old adults
Methods:
SARC-F questionnaire, handgrip dynamometry, calculation of SII and CAR
Exclusion Criteria:
Age <80 years, active malignancy, acute infection, immunodeficiency, advanced chronic kidney failure, cerebrovascular events, end-stage heart failure, trauma, psychiatric disorders
Running title:
Biomarker ratios for personalized therapeutic decisions
Authors:
Dejana Bajić; Nemanja Todorović; Mladena Lalić Popović; Ljiljana Andrijević
Affiliation:
Department of Biochemistry, Faculty of Medicine, University of Novi Sad; Department of Pharmacy, Faculty of Medicine, University of Novi Sad
Institution:
Institute for Pulmonary Diseases of Vojvodina, Clinic for Intensive Medicine and Vascular Pulmonary Diseases, Department for Intensive Care and Intoxications Level 3
Country:
Serbia
Corresponding author:
Dejana Bajić, MD, PhD
ORCID IDs:
0000-0002-7958-068X; 0000-0002-1519-5643; 0000-0001-8354-3868; 0000-003-0676-7985
Study design:
Retrospective observational clinical study
Study period:
November 2020 – February 2022
Sample size:
133 ICU patients with COVID-19-related sepsis
Primary endpoint:
28-day mortality
Biomarkers analyzed:
Neutrophil-to-lymphocyte ratio (NLR); Fibrinogen-to-albumin ratio (FAR); C-reactive protein-to-albumin ratio (CAR)
Statistical methods:
ROC curve analysis; logistic regression
Ethical approval:
Ethics Committee of the Institute for Pulmonary Diseases of Vojvodina (Protocol Code No. 9-II/3, February 24, 2022); Ethics Committee of the Faculty of Medicine, University of Novi Sad (Protocol Code No. 01-39/190/1)
Conflicts of interest:
None declared
Funding:
No financial support received
Keywords:
biomarkers; COVID-19; inflammation; prognosis
Year:
2023
Region / City:
Not specified
Subject:
Radiology, Musculoskeletal Imaging
Document Type:
Audit Report
Organization / Committee:
ESSR Arthritis Subcommittee, Royal College of Radiologists
Authors:
Dr KS Yung, Dr HM Kwok, Dr NY Pan
Target Audience:
Radiologists, Sonographers, Rheumatologists
Effective Period:
Six months prior to audit or most recent 50 cases
Approval Date:
11 August 2023
Last Reviewed:
1 August 2023
References:
Diekhoff T, Lambert R, Hermann KG (2022); Sudoł-Szopińska I, Jurik AG, Eshed I, et al. (2015); Lambert RG, Bakker PA, van der Heijde D, et al. (2016); Tsoi C, Griffith JF, Lee RKL, Wong PCH, Tam LS (2019); Mandl P, Navarro-Compán V, Terslev L, et al. (2015)
Standards:
MRI sequences for suspected inflammatory sacroiliitis should include coronal oblique T1-weighted and STIR/TIRM, with reporting of active and structural changes, lesion site, number, and location
Year:
2021
Region / City:
Shanghai, China
Topic:
Inflammatory myofibroblastic tumor, Metformin treatment
Document type:
Case report
Organization / Institution:
Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine
Author(s):
Yu Liang, Hong-Xiang Gao, Rui-Cheng Tian, Jing Wang, Yu-Hua Shan, Lei Zhang, Chen-Jie Xie, Jing-Jing Li, Min Xu, Song Gu
Target audience:
Medical professionals, researchers in oncology and pediatrics
Period of validity:
Not applicable
Approval date:
January 16, 2021
Modification date:
Not applicable
Year:
Not specified
Region / city:
Not specified
Topic:
Tumor immunology, treatment methods
Document type:
Scientific article
Organization / institution:
Not specified
Author:
Not specified
Target audience:
Researchers, Immunologists
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
2026
Region/Location:
Not specified
Subject:
Melanoma research
Document type:
Supplementary data tables
Institution:
Research laboratory / academic study
Author:
Not specified
Sample size:
NEVI (14), Primary Malignant Melanoma (23), Metastatic Melanoma (15)
Methods:
Immunohistochemistry for PD-L1, BRAF codon 600 genotyping, inflammatory scoring
Cell lines:
Human melanoma cultured cells
Treatment:
IFN-gamma induction
Data metrics:
%PD-L1 expression, inflammation score, ∆MFI for PD-L1 and MHC I
Context:
Archival melanoma tissue samples and cultured melanoma cell lines analyzed for PD-L1 expression, BRAF mutation status, and immune response markers in experimental study
Year:
2012–2018
Region:
International
Topic:
Inflammatory Bowel Disease, Meta-Analysis
Document Type:
Supplementary Tables
Institution:
Multiple Clinical Research Centers
Authors:
Sebkova, Vadan, De Vos, Molander, Dai, Echarri, Yu, Magro, Pinetun de Chambrun, Prymak, Zhang, Kaymak, Kumar, Munoz-Villafranca
Target Audience:
Clinicians and researchers in gastroenterology
Period Covered:
8 weeks to 2 years follow-up
Data Source:
Published studies included in meta-analyses
Assessment Tool:
Newcastle-Ottawa Scale (NOS)
Statistical Tests:
χ2-test, I2-test
Year:
Not specified
Region / city:
Not specified
Topic:
Medical conditions
Document type:
Educational material
Author:
Not specified
Target audience:
Medical students, healthcare professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Journal Name:
Asian Research Journal of Gynaecology and Obstetrics
Manuscript Number:
Ms_ARJGO_140463
Type of Article:
ORIGINAL RESEARCH ARTICLE
Authors:
Not specified
Reviewer:
Monisha C, Dr Rela Institute and Medical Center, India
Region:
Nasarawa, Nigeria
Research Focus:
Inflammatory markers and preeclampsia
Ethical Considerations:
Not specified
Language:
English
Target Audience:
Medical and scientific community
Date of Submission:
Not specified
Abstract Quality:
Comprehensive
Scientific Validity:
Confirmed
References:
Sufficient and recent
Note:
Date of Protocol Creation
Topic:
Developmental Disabilities
Document Type:
Protocol
Agency:
Developmental Disabilities Administration (DDA)
Target Audience:
Caregivers, Medical Personnel
Context:
A protocol document detailing emergency procedures, signs, symptoms, and treatments related to bowel-related emergencies for individuals with developmental disabilities, along with guidelines for monitoring and medication.
Note:
Year
Theme:
Healthcare
Document Type:
Healthcare Plan
Note:
Year
Organization:
Aruma
Document type:
Care Plan / Health Management
Target audience:
Aruma staff, treating health professionals
Participant details:
Name, Date of birth, Preferred name, Aruma ID
Health condition details:
Diagnosis, Medication requirements, Risk factors for constipation or faecal incontinence, Presence of Autism or stoma
Diet and fluid management:
Instructions, Monitoring requirements
Bowel management:
Daily schedule, Stool appearance reference, Actions required, Supplies needed
Monitoring and recording:
Bowel chart usage, Effectiveness review, Shift reporting
Review timeline:
Scheduled review period, Next review date, Signs for immediate review
Emergency management:
Faecal incontinence, Chronic constipation, Urinary tract infection, Skin integrity risks, Autonomic dysreflexia
Context:
Clinical care document outlining individualized bowel management procedures, risk monitoring, and emergency responses for participants requiring high-intensity support.
Year:
2018
Region / City:
Milton Keynes
Theme:
Healthcare policy for spinal cord injury (SCI) care
Document type:
Policy
Organization:
Spinal Injuries Association
Author:
Carol Adcock, Debbie Green
Target audience:
Healthcare providers, clinical staff, NHS trusts
Review date:
January 2023
Approval date:
July 2018
Revision date:
January 2025
Year:
2023
Region / City:
New Zealand
Topic:
Bowel cancer screening, interval cancers, screening sensitivity
Document Type:
Report
Organization:
New Zealand Cancer Registry
Author:
Not specified
Target Audience:
Healthcare professionals, researchers
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified