№ files_lp_3_process_9_44221
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Educational case study presenting clinical, genetic, structural, and biochemical analysis questions concerning a newborn diagnosed with a hemoglobin γ-chain V67M mutation associated with cyanosis and reported in a peer-reviewed medical journal.
Author:
Shuchismita Dutta
Institution:
Institute of Quantitative Biomedicine, Rutgers University, Piscataway NJ 08854
Geographic location:
Toms River, New Jersey, United States
Year of case:
2008
Year of publication:
2011
Journal referenced:
New England Journal of Medicine
Related article:
Patch (Toms River edition)
Medical focus:
Cyanosis in a newborn
Genetic focus:
Hemoglobin Toms River mutation (V67M in γ-globin)
Protein studied:
Fetal hemoglobin (α2γ2)
Research methods referenced:
DNA sequencing, structural analysis using Protein Data Bank, laser photolysis, rapid mixing kinetics
Protein database referenced:
Protein Data Bank
Structure visualization tool referenced:
iCn3D
Native protein structure referenced:
PDB ID 4MQJ
Biological system used:
Escherichia coli expression system
Type of document:
Educational case study with research analysis questions
Intended audience:
Students in biochemistry, molecular biology, or biomedical sciences
Subject area:
Molecular basis of cyanosis and hemoglobin mutation
Price: 8 / 10 USD
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Date:
1 March 2019
Event:
89th Geneva International Motor Show
Location:
Goodwood, West Sussex / Geneva, Switzerland
Artist:
Tomás Saraceno
Art Programme:
Rolls-Royce Art Programme
Artwork series:
Hybrid Web
Exhibition period:
7–17 March 2019 (Geneva), from 28 March 2019 (Goodwood)
Type of document:
Press release / Media information
Target audience:
Art and automotive enthusiasts, media
Collaborations:
Palais de Tokyo, Paris; Rolls-Royce Art Programme commissions
Context:
Contemporary art / Automotive showcase
Country:
Cape Verde
Programme Title:
The One Programme in Cape Verde
Sub-Programme:
Promotion of Growth and Economic Opportunities
Duration:
01 July 2008 – 31 December 2011
Starting Date:
01 July 2008
End Date:
31 December 2011
Thematic Areas:
Good Governance; Economic Growth and Competitiveness; Environment and Energy; Human Capital and Social Protection
Objectives:
Reduction of extreme poverty and hunger; promotion of economic growth, competitiveness, productive employment and socio-economic rights; reduction of dependency on ODA and Diaspora
Key Areas of Intervention:
International business environment; enterprise development; employment generation; integration of youth, women and vulnerable groups; institutional capacity building; statistical system development
Lead Agency:
UNIDO
Participating UN Agencies:
FAO; ILO; IOM; UNDP; UNESCO; UNFPA; UNHABITAT; UNICEF; UNIFEM
National Partners:
Ministry of Economy, Growth and Competitiveness; Central Bank; Ministry of Labor; Ministry of State Reform; Ministry of Environment, Rural Development and Marine Resources; Ministry of Culture; Ministry of Decentralization, Housing and Territory Planning; National Association of Municipalities; Ministry of Education; Chambers of Commerce; NGO Platform; Capeverdean Institute for Gender Equality and Equity; Trade Unions; Employers Union; INE; UNICV
Total Budget (2008–2011):
US$ 15,022,118
Available Funds (2008–2011):
US$ 6,893,563
Funding Gap (2008–2011):
US$ 8,128,555
2009 Sub-Programme Budget Available:
US$ 5,192,416
Total Spent by 31 December 2009:
US$ 2,609,389
Cape Verde Transition Fund Allocation:
US$ 863,795
Cape Verde Transition Fund Spent by 31 December 2009:
US$ 381,803
Expenditure Rate by 31 December 2009:
50.3% (Total Funds); 44.2% (Cape Verde Transition Fund)
Donors:
Cape Verde Transition Fund
Contact:
Rui Levy ([email protected]
), UN Building, Ave OUA – Achada Santo Antonio, PO Box 62, Tel:
(238) 260 96 00 / 260 96 01
Year:
2008–2011
Country:
Pakistan
Project Type:
National Implementation Modality (NIM)
Funding Organization:
United Nations Development Program (UNDP)
Implementing Agency:
Wafaqi Mohtasib Secretariat (WMS)
Project Oversight:
Project Oversight Board (POB) chaired by Honorable Wafaqi Mohtasib (HWM)
Budget:
US$ 1.6 million (original), US$ 0.9 million (actual expenditure)
Project Duration:
June 2008 – December 31, 2011
Objectives:
Improve grievance redress mechanisms, enhance public demand for accountability, transparency and integrity (ATI), facilitate access to information on service delivery
Outputs:
Improved institutional capacities, enhanced public interface, strengthened ATI coordination, effective knowledge management
Evaluation Criteria:
Relevance, Effectiveness, Efficiency, Expected Impact, Sustainability
Methodology:
Document review, interviews, analysis of project research papers and standard operating procedures
Year:
2008–2019
Thematic Area:
Public administration, parliamentary development, public financial oversight
Document Type:
Recommendations and management response record
Organization:
United Nations Development Programme (UNDP)
Institutional Context:
Parliamentary support and public administration projects
Responsible Roles:
Project Manager(s) of the Project under the relevant Outcome; Programme Analyst
Geographic Context:
Georgia
Related Institution:
Chamber of Control of Georgia (CCG)
Key Topics:
Monitoring system introduction; sustainability of institutional financing; parliamentary outreach offices; donor support strategy; institutional needs analysis
Associated Events:
Parliamentary elections of May 2008
Implementation Tracking:
Key actions, responsible officials, due dates, status updates, and comments
Status of Actions:
Completed
Update History:
Entries added 11 February 2008; updates recorded through 19 March 2019
Year:
Not specified
Region / City:
Not specified
Topic:
Health / Medical
Document Type:
Medical guideline
Author:
Not specified
Target Audience:
Healthcare professionals
Action Period:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2007
Region / City:
New Mexico
Topic:
Hemoglobin Function, High-altitude Adaptation, Physiological Studies
Document Type:
Laboratory Instructions, Academic Paper
Organization / Institution:
University of New Mexico
Author:
J.F. Storz
Target Audience:
Students, Researchers in Biology
Period of Action:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2026
Study type:
Observational cohort study
Population:
Surgical patients
Sample size:
8060
Data type:
Clinical, laboratory, perioperative
Variables analyzed:
Demographics, comorbidities, surgical features, intraoperative transfusions, laboratory values, bleeding risk factors, perioperative vasopressors, intravenous fluids, postoperative outcomes
Statistical methods:
Multivariable linear and logistic regression
Outcome measures:
Hospital-free days, ICU-free days, invasive ventilation, mechanical ventilation, acute kidney injury, ICU admission, in-hospital mortality, myocardial and cerebral ischemia
Data collection period:
Not specified
Institution:
Not specified
Source type:
Supplemental tables from clinical research
Year:
2022
Region / city:
Global
Topic:
Hemoglobin concentration, altitude, age-pregnancy groups
Document type:
Research Supplementary Information
Institution:
HemaSphere
Author:
Not specified
Target audience:
Researchers in the field of hematology and epidemiology
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Note:
Description
Year:
Not specified
Region / City:
UK
Topic:
Diabetes, Glycated Hemoglobin, Cancer Risk
Document Type:
Research Supplementary Table
Institution:
UK Biobank
Author:
Not specified
Target Audience:
Researchers, Healthcare Professionals
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified