№ files_lp_4_process_3_107148
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Pharmacodynamic modeling was applied to evaluate sunscreen efficacy and related risks of sunburn and melanoma using a new Skin UV Index (SUI) parameter, with implications for appropriate SPF recommendations based on application practices.
Year: 2020
Region / city: United States, Illinois
Theme: Sunscreen efficacy, sunburn, melanoma, skin protection
Document type: Academic article
Organization / institution: Chiou Consulting Inc, National Institutes of Health
Author: Win L. Chiou
Target audience: Researchers, healthcare professionals, public health experts
Effective period: 2020
Approval date: March 27, 2020
Modification date: Not specified
Keywords: sunscreen, sunburn, melanoma, skin aging/antiaging theory, UV Index, skin cancers
Price: 8 / 10 USD
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Supplemental Digital Content: Pharmacokinetic and Pharmacodynamic Analyses of Meropenem in Pediatric Patients with Sepsis
Year: 2018
Country: United States
Subject: Pharmacokinetics and pharmacodynamics of meropenem in pediatric sepsis
Document Type: Supplemental scientific tables and figures
Drug: Meropenem
Pathogen Focus: Pseudomonas aeruginosa
Data Source: SENTRY Antimicrobial Surveillance Program
Study Population: Children younger than 17 years
Clinical Condition: Sepsis
Parameters Analyzed: Observed volume of distribution (Vz_obs), observed clearance (Cl_obs), minimum inhibitory concentration (MIC), pharmacodynamic target attainment (T>MIC), estimated glomerular filtration rate (eGFR), fluid balance
Dosage Regimens Evaluated: 20 mg/kg, 40 mg/kg, 60 mg/kg
Evaluation Period: Day 1 to Day 3 after start of meropenem infusion
Geographic Scope of Isolate Data: United States medical centers
Topics: Sunscreens Sunburn Pharmacodynamic