№ files_lp_4_process_1_48340
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Longitudinal cohort study reporting the evolution of lung function in HIV-infected children aged 6–16 years in Zimbabwe, comparing ART-naïve and ART-established groups to assess associations of therapy initiation timing and nutrition with lung development.
Year:
2013–2015
Location:
Harare, Zimbabwe
Topic:
Pediatric HIV and respiratory health
Document type:
Research article
Institution:
Biomedical Research and Training Institute; Liverpool School of Tropical Medicine; London School of Hygiene and Tropical Medicine; University of Zimbabwe; University of Oxford
Authors:
Sarah Rylance, Jamie Rylance, Grace McHugh, Edith Majonga, Tsitsi Bandason, Hilda Mujuru, Kusum Nathoo, Sarah Rowland-Jones, Marc Y. R. Henrion, Victoria Simms, Rashida A. Ferrand
Funding:
Wellcome Trust, grant no 095878/Z/11Z
Target population:
Children and adolescents aged 6–16 years living with HIV
Study type:
Prospective cohort
Sample size:
468 participants
Follow-up period:
2 years
Data collection:
Spirometry, socio-demographic questionnaire, clinical history
Intervention:
Antiretroviral therapy initiation timing
Ethics approval:
Medical Research Council of Zimbabwe, Harare City Health Department Ethics Committee, London School of Hygiene and Tropical Medicine Ethics Committee, Biomedical Research and Training Institute Institutional Review Board
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Year:
2026
Region / City:
United States
Topic:
Antiretroviral Therapy (ART)
Document Type:
Proposal
Institution:
MO HealthNet
Author:
MO HealthNet, Conduent
Target Audience:
Healthcare professionals, policymakers, and health program administrators
Effective Period:
2026–
Approval Date:
January 20, 2026
Revision Date:
April 7, 2022
Year:
2021
Region / City:
Global
Topic:
Pediatric HIV Treatment
Document Type:
Guideline
Organization:
World Health Organization (WHO)
Author:
World Health Organization (WHO)
Target Audience:
Healthcare workers, caregivers, HIV service providers, ministries of health
Period of Application:
Ongoing
Approval Date:
2021
Date of Changes:
Not specified
Year:
not specified
Language:
English
Topic:
HIV-1 treatment
Therapeutic regimen:
Long-acting injectable antiretroviral therapy
Medication:
Cabenuva (cabotegravir and rilpivirine)
Drug classes:
Integrase strand transfer inhibitor; non-nucleoside reverse transcriptase inhibitor
Route of administration:
Intramuscular gluteal injection
Dosing schedules:
Every 4 weeks; every 8 weeks
Target population:
Adults with HIV-1 infection
Eligibility criteria:
Virologically suppressed patients without relevant drug resistance
Exclusion criteria:
Pregnancy, breastfeeding, specific drug interactions, hypersensitivity
Monitoring requirements:
HIV viral load, CMP, CBC
Clinical setting:
Clinic-administered therapy
Healthcare roles:
Provider, case manager, registered nurse, pharmacy
Regulatory reference:
FDA labeling
Source adaptation:
Ward 86 Long-Acting Injectable ARV Protocol
Year:
2017
Region / City:
KwaZulu-Natal, South Africa
Topic:
HIV prevention, Antiretroviral therapy, Young female-sex workers
Document Type:
Research report, Implementation study
Organization / Institution:
BMJ, StaRI Group
Author:
Pinnock H, Barwick M, Carpenter C, Eldridge S, Grandes G, Griffiths CJ, Rycroft-Malone J, Meissner P, Murray E, Patel A, Sheikh A, Taylor SJC
Target Audience:
Researchers, Healthcare professionals, Public health practitioners
Period of validity:
Not specified
Approval date:
2017
Date of changes:
Not specified
Year:
2021
Region / city:
Johannesburg, Gauteng, RSA
Subject:
HIV drug resistance, antiretroviral therapy
Document type:
Research study
Institution:
South African National Health Laboratory Service, Toga laboratories (Pty) Ltd
Author:
Hermans LE, Nijhuis M, Tempelman HA, et al.
Target audience:
Researchers, healthcare professionals, policymakers
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Country:
Nigeria
City / Region:
Port Harcourt, Rivers State
Research Location:
Rivers State University Teaching Hospital (RSUTH); University of Port Harcourt Teaching Hospital (UPTH)
Subject Area:
Hematology; Hemostasis; HIV/AIDS Research
Type of Document:
Scientific Research Article
Study Population:
Human Immunodeficiency Virus-Positive subjects aged 20–79 years
Sample Size:
150 participants
Study Groups:
First-line regimen (Abacavir Lamivudine Dolutegravir); Second-line regimen (Tenofovir Lamivudine Dolutegravir); Naïve HIV-positive control group
Medical Conditions Studied:
Human Immunodeficiency Virus (HIV); hematologic abnormalities; haemostatic abnormalities
Laboratory Methods:
Sysmex XP-300 Automated Haematology Analyzer; Enzyme Linked Immunosorbent Assay (ELISA); Prothrombin Time (PT); Activated Partial Thromboplastin Time (APTT)
Statistical Analysis:
Student’s independent t-test; Analysis of Variance (ANOVA); Microsoft Office Excel 2007; GraphPad Prism 6.2
Measured Parameters:
White blood cell count; lymphocyte count; haemoglobin; neutrophil-to-lymphocyte ratio; prothrombin time; activated partial thromboplastin time; D-dimer levels
Study Objective:
Assessment of hematologic and haemostatic profiles in HIV-positive subjects receiving different antiretroviral regimens
Keywords:
Hematologic; Haemostatic; Human Immunodeficiency Virus-Positive Subjects; Antiretroviral regimen; First-line; Second-line; Naïve
Year:
2023
Region / city:
UK
Theme:
Oncology, Lung Cancer, Treatment Guidelines
Document type:
Clinical guidelines
Organization / institution:
NICE
Author:
NICE
Target audience:
Healthcare professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Contextual description:
Detailed clinical guidelines outlining the recommended systemic treatments for advanced non-small-cell lung cancer based on disease progression and previous therapies.
Service:
Lung Cancer Whole Pathway
Document type:
Commissioning guidance
Health system:
NHS England
Period:
2024/25
Date of review:
April 2026
Scope:
Direct and specialised commissioning
Clinical focus:
Lung cancer
Geographical context:
United Kingdom
Policy context:
NHS Long Term Plan
Related pathway:
National Optimal Lung Cancer Pathway
Commissioning themes:
Early diagnosis, reducing variation, living with cancer
Evidence base:
NICE guidance and national standards
Note:
Year
Topic:
Lung disease, steroid treatment
Document type:
Information sheet
Organization / institution:
Sheffield Teaching Hospitals NHS Foundation Trust
Author:
Respiratory and endocrinology teams
Target audience:
People with lung disease on high dose inhaled steroids
Year:
2025
Region / City:
Shropshire, Telford and Wrekin
Subject:
Targeted Lung Healthcare Checks (TLHC), Procurement Process, NHS Contract Award
Document Type:
Panel Review
Organization:
NHS Shropshire, Telford and Wrekin Integrated Care Board (STW ICB)
Author:
Independent Patient Choice and Procurement Panel
Target Audience:
Healthcare providers, stakeholders in public sector procurement, regulatory bodies
Period of Validity:
1 March 2025 - 28 February 2027 (contract term, with extension option)
Approval Date:
25 November 2024
Amendment Date:
21 March 2025
Year:
2024/25
Region / City:
UK
Topic:
Lung Cancer Pathway
Document Type:
Commissioning Guidance
Author:
Not specified
Target Audience:
Healthcare professionals, commissioners, and providers in the NHS
Period of Validity:
2024/25
Approval Date:
Not specified
Review Date:
April 2025
Year:
2025
Program name:
DataLung – DZL Data Science School for Lung Researchers
Organization:
Deutsches Zentrum für Lungenforschung (DZL)
Target group:
DZL Academy fellows in lung research
Eligibility requirements:
Basic Python skills or numerical background depending on track; lung-related research project
Program tracks:
BioTrack; CompuTrack
Application deadline:
February 21, 2025
Notification date:
March 18, 2025
Contract requirement:
Employment contract valid until April 2027
Key dates:
April 14–16, 2025; October 13–17, 2025; October–December 2025
Locations:
Schloß Rauischholzhausen; Munich; virtual
Application materials:
CV/Biosketch; research project description; computational track record
Submission method:
Email submission with supervisor consent
Contact email:
[email protected]
Source type:
Call for applications for an academic training program
Year:
2021
Region / city:
Australia
Topic:
Oncology / Pharmaceutical
Document Type:
Submission
Agency:
Pharmaceutical Benefits Advisory Committee (PBAC)
Author:
AstraZeneca Pty Ltd
Target Audience:
Medical professionals, regulatory authorities
Validity Period:
2021-2026
Approval Date:
20 April 2021
Modification Date:
Not specified
Year:
2023
Region / City:
Australia
Topic:
Oncology, Pharmaceutical Submission
Document Type:
Pharmaceutical Resubmission
Organization:
AstraZeneca Pty Ltd
Author:
Not specified
Target Audience:
Medical Practitioners
Period of Validity:
Ongoing
Approval Date:
Not specified
Date of Changes:
Not specified
Context:
A pharmaceutical resubmission document outlining the use of osimertinib as a first-line treatment for locally advanced or metastatic EGFRm non-small cell lung cancer (NSCLC) in Australia, including previous PBAC considerations and clinical trial data.
Year:
2016
Region / city:
New Zealand
Topic:
Lung Cancer, Healthcare Services
Document type:
Standards/Guidelines
Institution:
Ministry of Health
Author:
National Lung Cancer Working Group
Target audience:
Healthcare professionals, primary care providers, policymakers
Effective period:
2016
Approval date:
2016
Amendment date:
2016
ISBN:
978-0-947515-12-6
Language:
English
Year:
2023
Region / City:
N/A
Topic:
Lung Cancer Treatment, Immunotherapy
Document Type:
Research Paper
Author:
Ayush Chalishajar
Target Audience:
Researchers, Medical Professionals, Academics
Period of Action:
January 15th - March 19th
Approval Date:
N/A
Date of Changes:
N/A
Year:
2019
Region / city:
Australia
Topic:
Oncology, Lung Cancer Management
Document Type:
Educational Course
Organization:
Cancer Australia, eviQ Education
Author:
Cancer Australia
Target Audience:
Health professionals working in the oncology setting or involved in the care of lung cancer patients
Action Period:
May 2019 – May 2020
Approval Date:
Not specified
Date of Changes:
Not specified
Project Phases:
Stage 1 (sections 1-3), Stage 2 (sections 4-5), Stage 3 (sections 6-8)
Clinical Advisory Committee:
Yes
External Review Group:
Yes
Course Format:
eLearning series
Content Areas:
Prevention, Screening, Diagnosis, Treatment, Symptoms Management, End of Life Care, Survivorship
Time Frames:
Estimated start and end dates for stages, review periods for committees
Contact Information:
[email protected]
Expressions of interest closing date:
May 26
Year:
2026
Region / city:
Chermside, Queensland, Australia
Theme:
Lung cancer research, biorepository
Document type:
Research article
Organization / institution:
UQ Thoracic Research Centre, The Prince Charles Hospital
Author:
Anita Goldsworthy, Kelly Chee, Linda Passmore, Jaccalyne Brady, Barbara Page, Maria Martins, Edward Stephens, Caeli Zahra, Edwina Duhig, Ian Yang, Henry Marshall, Justin Tan, Morgan Windsor, Rishendran Naidoo, David Godbolt, Kwun M Fong
Target audience:
Researchers, clinicians, cancer specialists
Action period:
Ongoing
Approval date:
Not specified
Date of changes:
Not specified
Year:
2026
Region / city:
Not specified
Topic:
Toxicity, drug efficacy
Document type:
Scientific figure
Organization / institution:
Not specified
Author:
Not specified
Target audience:
Researchers, scientists
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Date of decision to refer:
${createdDate}
Note:
Date referral received at Trust
Hospital selection:
University Hospital Dorset (UHD), Dorset County Hospital (DCH), Salisbury NHS Foundation Trust
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Title:
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Clotting:
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