№ lp_2_3_20820
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Psychiatric rehabilitation focuses on a range of interventions aimed at improving the quality of life, social functioning, and recovery for individuals with schizophrenia through various therapeutic strategies.
Year:
2023
Region / city:
Rohtak, Haryana
Topic:
Schizophrenia, Psychiatric Rehabilitation
Document Type:
Research Article
Organization / Institution:
Institute of Mental Health, Pt. B.D. Sharma University of Health Sciences, PGIMS
Author:
Dr. Aakanksha Kharb, Dr. Nandini Lamba, Dr. Pradeep Kumar
Target Audience:
Mental Health Professionals, Researchers, Medical Students
Period of Action:
Ongoing
Approval Date:
Not specified
Date of Changes:
Not specified
Price: 8 / 10 USD
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Type of document:
Pharmaceutical Benefits Advisory Committee (PBAC) submission and assessment report
Medicine:
Aripiprazole long-acting injectable (AOM)
Dosage forms/strengths:
Powder for injection 300 mg (as monohydrate) with diluent in pre-filled dual-chamber syringe; Powder for injection 400 mg (as monohydrate) with diluent in pre-filled dual-chamber syringe
Brand:
Abilify Maintena
Sponsor:
Lundbeck Australia Pty Ltd
Purpose of submission:
Request for General Schedule Authority Required (STREAMLINED) PBS listing of AOM pre-filled syringe dose form
Indication:
Treatment of schizophrenia
Comparator:
AOM modified release injection vial kit (therapeutic vial kits)
Regulatory status:
TGA registered 7 May 2018 for acute and maintenance treatment of schizophrenia in adults and maintenance treatment of bipolar I disorder (monotherapy)
Previous PBAC consideration:
400 mg AOM PFS recommended July 2018; recommendation rescinded March 2023
Pricing basis:
Cost-minimisation versus AOM vial kit with equivalent pricing (no price premium)
Price levels referenced:
DPMQ, PTP, AEMP (current as of 1 June 2025)
Estimated PBS usage:
400,000 to <500,000 scripts over first six years (Year 1 10,000–<20,000; Year 6 100,457)
Indication listing conditions:
Authority Required (Streamlined); prescriber types include medical practitioners and nurse practitioners; general schedule (Code GE)
Version:
2.1
Executive Lead:
Executive Director of Quality and Medical Leadership
Lead Author:
Principal Clinical Pharmacist
Approved Date:
14/11/2022
Approved By:
Drugs and Therapeutics Committee (DTC)
Ratified Date:
14/11/2022
Ratified By:
Drugs and Therapeutics Committee (DTC)
Issue Date:
08/02/2023
Expiry Date:
14/11/2025
Target Audience:
Clinical staff
Document Type:
Guidelines
Ratifying Committee:
Drugs and Therapeutics Committee (DTC)
Review Date:
14/11/2025
Summary of significant changes from previous version:
Minor amendments: References to Xeplion® LAI in the document changed to Paliperidone monthly LAI as generic version available
Purpose:
Provide clinical staff with clear guidance on prescribing antipsychotics for the management of psychosis / schizophrenia in adults.
Date:
10 October 2014
Event:
World Mental Health Day
Theme:
Living with schizophrenia
Institution:
University of Cape Town
Department:
Department of Psychiatry and Mental Health, University of Cape Town
Issued by:
UCT Communication and Marketing Department
Media Liaison Officer:
Kemantha Govender
Location:
Rosebank, South Africa
Research Focus:
Genetic and neuroscientific studies on schizophrenia
Population Studied:
Xhosa population of South Africa
Type of Document:
Press release
Contact Information:
Tel (021) 650 5672; Cell (084) 737 6522; [email protected]
Note:
Year
Theme:
Mental Health / Schizophrenia / Text Messaging
Document Type:
Moderator’s Guide
Author:
Michele
Target Audience:
People with Schizophrenia, Mental Health Professionals
Context:
A moderator’s guide for gathering feedback from individuals with schizophrenia on the effectiveness of text messaging for relapse prevention and symptom monitoring.
Year:
2023
Region / City:
Nanjing, Jiangsu Province, China
Topic:
Neuroscience, Psychiatry, Schizophrenia, Bipolar Disorder
Document Type:
Research Article
Organization / Institution:
Affiliated Brain Hospital of Nanjing Medical University
Author:
Yilin Tang, Ruiqiu Zhu, Yucheng Ling, Yifan Wang, Yingbo Dong, Peiyu Cao, Yuting Li, Qi Si, Guoxin Xu, Zhuma Jin, Yuxiu Sui
Target Audience:
Psychiatry researchers, neuroscientists, medical professionals
Period of Activity:
2023
Date of Approval:
2023
Date of Changes:
Not specified
Keywords:
Schizophrenia, Bipolar disorder, Psychosis symptoms, MRI, Basal ganglia
Abstract:
This study investigates the volume changes of basal ganglia subregions in patients with schizophrenia (SCZ), bipolar disorder (BD), and healthy controls (HC), with a focus on the relationship between these changes and psychotic symptoms.
Species accumulation curve and diversity indices comparison between schizophrenia and control groups
Year:
2026
Region / city:
Not specified
Subject:
Schizophrenia, Metabolomics
Document type:
Research figure and table
Organization / institution:
Not specified
Author:
Not specified
Target audience:
Researchers in schizophrenia and metabolomics
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
Not specified
Region / City:
Not specified
Topic:
Neurological Disorders, Psychiatry, Neuroimaging
Document Type:
Scientific Supplementary Figure
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Researchers, Clinicians
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Contextual Description:
A scientific supplement detailing post-hoc comparisons of FAT and FW between healthy controls, adolescent-onset schizophrenia, and adolescent-onset bipolar disorder with psychosis, using neuroimaging data.
Year:
2023
Region / City:
Global
Topic:
Mental Health, Psychosis, Schizophrenia
Document Type:
Research Protocol / Search Strategy
Organization:
N/A
Author:
N/A
Target Audience:
Researchers, Mental Health Professionals
Effective Period:
N/A
Approval Date:
N/A
Revision Date:
N/A
Keywords:
psychosis, schizophrenia, risk, treatment, early intervention, qualitative research, search strategy
Year:
2001
Region / City:
United States
Theme:
Mental health, biography, film study
Document Type:
Educational assignment / discussion guide
Institution:
High school / college classroom
Author:
Not specified
Target Audience:
Students studying psychology or film
Related Work:
Film "A Beautiful Mind" directed by Ron Howard
Topics Covered:
Schizophrenia, biography, character analysis, treatment methods, critical thinking
Date Assigned:
Not specified
Due Date:
Friday (as mentioned in text)
Year:
2026
Region / City:
Not specified
Subject:
Mental Health / Psychiatry
Document Type:
Clinical Treatment Outline
Institution / Organization:
Not specified
Author:
Not specified
Target Audience:
Mental health professionals
Period of Application:
Initial and ongoing treatment phase
Diagnosis:
F20.9 Schizophrenia
Treatment Goals:
Social, relational, occupational improvement
Assessment Requirements:
Initial clinical assessments as needed
Therapist Characteristics:
Empathy, consistency, reliability
Treatment Location:
Facility-based or therapist’s office depending on patient needs
Interventions:
Role-playing, exposure exercises, individual therapy sessions
Treatment Emphasis:
Interpersonal and occupational skills
Treatment Nature:
Individual therapy, possible family involvement
Frequency and Duration:
Weekly sessions for 6–12 months
Medications:
Antipsychotics as prescribed
Adjunct Services:
Occupational therapy, medical monitoring
Prognosis:
Recovery defined by functional and social improvements; outcome depends on therapeutic relationship and adherence
Note:
Year
Contextual description:
A scientific paper presenting supplementary methods related to polygenic analysis and causal inference in the relationship between loneliness, isolation, and schizophrenia.
Year:
2018
Region / Institution:
National University of Ireland Galway, Ireland
Subject:
Cognitive training, schizophrenia, neuroimaging
Document type:
Systematic review and meta-analysis
Authors:
David Mothersill, Gary Donohoe
Corresponding author:
Gary Donohoe, Professor of Psychology, School of Psychology, National University of Ireland Galway
Number of studies reviewed:
31
Neuroimaging methods:
fMRI, SPECT, PET, cortical thickness, VBM, DTI
Key findings:
Increased left prefrontal activation, distributed neural effects
Keywords:
neuroimaging; cognitive remediation therapy; psychosis; prefrontal
Word count abstract:
225
Word count main text:
3,007
Figures:
2
Tables:
2
Supplemental information:
1
Time period covered:
studies published until December 2018
Year:
2011
Region / city:
EU
Topic:
Efficacy data and information in plant protection product registration
Document type:
Technical Guidance Paper
Institution:
ECPA
Author:
ECPA
Target audience:
Applicants in plant protection product registration
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Contextual description:
A technical guidance paper outlining the preparation of concise efficacy summaries for plant protection product registration in the EU regulatory zone.
Year:
2023
Region / City:
Northern Ireland, UK; Sfax, Tunisia
Theme:
Antimicrobial agents, Biosurfactants, Oral hygiene
Document Type:
Research article
Institution:
Ulster University, University of Sfax
Author:
Mohamed Elshikh, Scott Funston, Alif Chebbi, Syed Ahmed, Roger Marchant, Ibrahim M. Banat
Target Audience:
Researchers, Biomedical professionals
Period of Validity:
N/A
Approval Date:
N/A
Modification Date:
N/A
Year:
2017
Region / city:
Moscow
Subject:
Medical products, Registration, Electronic documents
Document type:
Board Decision
Institution:
Eurasian Economic Commission
Author:
Eurasian Economic Commission Board
Target audience:
Business entities, Authorized authorities of the Member States
Period of validity:
Indefinite
Approval date:
June 30, 2017
Date of amendments:
Not specified
Year:
2026
Region / City:
United States
Topic:
Urgency urinary incontinence treatment
Document Type:
Clinical trial report
Institution:
Multiple U.S. medical centers
Authors:
Alexandra Rogers, MD; Rebecca McCrery, MD; Scott MacDiarmid, MD; Subhro Sen, MD; James Lukban, DO; Bilal Kaaki, MD; Andrew Shapiro, MD; Thomas Giudice, MD; John Nguyen, MD; Joseph Gauta, MD; Scott Serels, MD; Chris Threatt, MD; Jed Kaminetsky, MD; Vincent Lucente, MD; Sonia Dutta, MD; Peter Sand, MD; Kimberly Ferrante, MD
Study Design:
Prospective, multi-center, single-arm trial
Participants:
133 adults aged 18-80 with daily UUI episodes
Intervention:
Subcutaneous tibial neurostimulator (eCoin) implantation
Primary Outcome:
≥50% improvement in UUI episodes at 48 weeks
Secondary Outcomes:
3-day voiding diary data, patient-reported outcomes
Procedure Time:
20.8 minutes
Safety:
One serious device-related adverse event (localized infection resolved by explant)
Year:
2025
Region / city:
Not specified
Topic:
Antibiotic efficacy, nanotechnology
Document type:
Research article
Organization / institution:
Not specified
Author:
Diana Marcos Fernandez, Natalia Alfaro, Andrea Cutró, Diego Pazos-Castro, Inés Oliver Camacho, Luis Tebar Palmero, Ana Bouchet, Axel Hollmann
Target audience:
Researchers, healthcare professionals, microbiologists
Effective period:
Not specified
Approval date:
Not specified
Modification date:
Not specified
Year:
2023
Region / city:
USA, UK, AUS, ITA, PL, JP, KR
Topic:
Medical Research
Document Type:
Research Article
Institution:
Multiple medical institutions
Author:
M. Lia Palomba, Manish R. Patel, Toby A. Eyre, Wojciech Jurczak, et al.
Target Audience:
Medical professionals, researchers
Period of validity:
Not specified
Approval Date:
Not specified
Date of amendments:
Not specified
Year:
2017
Region / City:
Chennai, Tamil Nadu, India
Topic:
Antimicrobial research, oral pathogens
Document Type:
Research article
Author:
Murali Iyangar Radhika, Devaraj Ezhilarasan, Prakasam Gopinath
Target Audience:
Researchers, microbiologists, pharmacologists
Period of Validity:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified