№ lp_2_1_10898
Interim clinical trial results show that subcutaneous eCoin implantation significantly reduces urgency urinary incontinence episodes and symptom bother scores over 24 weeks in mostly female adults.
Year: 2026
Region / City: United States
Topic: Urgency urinary incontinence treatment
Document Type: Clinical trial report
Institution: Multiple U.S. medical centers
Authors: Alexandra Rogers, MD; Rebecca McCrery, MD; Scott MacDiarmid, MD; Subhro Sen, MD; James Lukban, DO; Bilal Kaaki, MD; Andrew Shapiro, MD; Thomas Giudice, MD; John Nguyen, MD; Joseph Gauta, MD; Scott Serels, MD; Chris Threatt, MD; Jed Kaminetsky, MD; Vincent Lucente, MD; Sonia Dutta, MD; Peter Sand, MD; Kimberly Ferrante, MD
Study Design: Prospective, multi-center, single-arm trial
Participants: 133 adults aged 18-80 with daily UUI episodes
Intervention: Subcutaneous tibial neurostimulator (eCoin) implantation
Primary Outcome: ≥50% improvement in UUI episodes at 48 weeks
Secondary Outcomes: 3-day voiding diary data, patient-reported outcomes
Procedure Time: 20.8 minutes
Safety: One serious device-related adverse event (localized infection resolved by explant)
Price: 8 / 10 USD
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