№ files_lp_4_process_2_73547
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Methodological appendix describing experimental procedures used to characterize the binding kinetics, enzymatic inhibition activity, and cellular effects of the anti-CD39 antibody AB598 in biochemical assays and human cell-based systems related to solid tumor research.
Year: Not specified
Country: United States
Institution: Arcus Biosciences, Inc.
Location: Hayward, California
Document Type: Scientific methodological supplement
Research Field: Cancer immunotherapy; molecular and cellular biology
Subject: Experimental characterization of the anti-CD39 antibody AB598
Author: Amy E. Anderson; Kaustubh Parashar; Ke Jin; Julie Clor; Carlo E. Stagnaro; Urvi Vani; Jaskirat Singh; Ada Chen; Yihong Guan; Priyanka Talukdar; Pavithra Sathishkumar; Damie J. Juat; Hema Singh; Ritu Kushwaha; Xiaoning Zhao; Angelo Kaplan; Lisa Seitz; Matthew J. Walters; Ester Fernandez-Salas; Nigel P. C. Walker; Christine E. Bowman
Corresponding Author: Christine E. Bowman
Organization Address: Arcus Biosciences Inc., 3928 Point Eden Way, Hayward, CA 94545
Contact Email: [email protected]
Contact Phone: 510-694-6200
Biological Target: CD39 (ENTPD1)
Experimental Techniques: Surface plasmon resonance (SPR); flow cytometry; luminescence assays; CRISPR knockout; qPCR; western blot
Biological Materials: Human monocytes; PBMCs; B cells; SK-MEL-5 cells; MOLP8 cells; whole blood from healthy donors
Study Focus: Binding kinetics, enzymatic inhibition, ATP hydrolysis, and CD39 surface expression following exposure to AB598
Price: 8 / 10 USD
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IQCP for Minimal Inhibitory Concentration (MIC)-based Antimicrobial Susceptibility Testing (AST) System XYZ
Note: Year
Quantitative Structure-Activity Relationship for Thiazolidine-2,4-Dione Derivatives as Inhibitory Activities of 15-PGDH Using MLR and ANN
Year: 2021
Region / City: Oran, Algeria; Biskra, Algeria; Casablanca, Morocco
Topic: Medicinal Chemistry, Quantitative Structure-Activity Relationship (QSAR), Drug Discovery
Document Type: Research Paper
Institution: Université des Sciences et de la Technologie d’Oran Mohamed BOUDIAF (USTO-MB), University of Biskra, Hassan II University of Casablanca
Author: Sihem MEDJAHED, Salah BELAIDI, Noureddine TCHOUAR, Houmam BELAIDI, Fatima SOUALMI, Samir CHTITA
Target Audience: Researchers in medicinal chemistry and computational chemistry
Period of Validity: 2021
Approval Date: Not specified
Modification Date: Not specified
Effects of Inhibitory Control on Academic Engagement of Tertiary Institutions’ Undergraduates in FCT Abuja, Nigeria
Authors: Aliyu Umar Yanda; Giwa Muyibat Omobolanle
Academic qualification: Ph.D (Aliyu Umar Yanda)
Affiliation: Department of Educational Psychology, FCT College of Education, Zuba, Abuja
Region / city: Abuja, Federal Capital Territory (FCT)
Country: Nigeria
Academic field: Educational Psychology
Research topic: Inhibitory control and academic engagement among undergraduates
Type of document: Academic research article
Research design: Quasi-experimental design with pre-test, post-test and control groups
Population: Undergraduates in tertiary institutions in FCT Abuja (85,188)
Sample size: 371 undergraduates
Sampling method: Multi-stage sampling
Data collection instrument: Undergraduate Academic Engagement Survey Instrument (UAES) and Inhibitory Control Treatment (ICT)
Statistical analysis: Paired sample t-test at 0.05 significance level
Reliability analysis: Cronbach Alpha (0.78 and 0.68)
Content validity coefficient: 0.82 and 0.78
Keywords: Academic Engagement, Inhibitory Control, Undergraduate, Control Group, Experimental Group
Topics: AB598 CD39 Inhibitory