№ files_lp_4_process_3_139586
Scientific review article analyzing the biological properties and pathogenic roles of the hepatitis E virus open reading frame 3 protein, including its involvement in virion release, formation of quasi-enveloped particles, modulation of host innate immunity, and interaction with cellular signaling pathways.
Year: 2021
Journal: World Journal of Gastroenterology
Manuscript type: Review article
Scientific field: Virology; Gastroenterology; Infectious diseases
Topic: Hepatitis E virus ORF3 protein and its biological functions
Authors: Yong-Lin Yang; Yu-Chen Nan
Corresponding author: Yu-Chen Nan
Country of authors: China
Funding: National Natural Science Foundation of China; Medical Science and Technology Development Foundation of Nanjing Department of Health
Received: January 23, 2021
Revised: March 10, 2021
Accepted: April 12, 2021
Published online: May 21, 2021
Publisher: Baishideng Publishing Group Inc.
DOI: 10.3748/wjg.v27.i20.2458
Keywords: Hepatitis E virus; Zoonosis; Quasi-enveloped virion; Hepatitis E virus-open reading frame 3; Innate immunity
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