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Review article summarizing experimental and clinical research on the anti-tumor effects of ginger on various gastrointestinal cancers, detailing molecular mechanisms, therapeutic potential, and historical context of medicinal food use in traditional Chinese medicine.
Year:
2023
Journal:
World Journal of Gastrointestinal Oncology
Manuscript Number:
86810
Type:
Review
Authors:
Guo-Qing Chen, Yi Nan, Shi-Cong Huang, Na Ning, Yu-Hua Du, Dou-Dou Lu, Ya-Ting Yang, Fan-Di Meng, Ling Yuan
Affiliations:
College of Pharmacy, Ningxia Medical College; Key Laboratory of Ningxia Ethnomedicine Modernization, Ministry of Education, Ningxia Medical University; Traditional Chinese Medicine College, Ningxia Medical University; School of Clinical Medicine College, Ningxia Medical University
Funding:
Young Scholars of Western China, West Light Foundation of the Chinese Academy of Sciences (No. XAB2019AW13); Ningxia Natural Science Foundation (No. 2022AAC02039)
Corresponding Author:
Ling Yuan, PhD, College of Pharmacy, Ningxia Medical College, Yinchuan, Ningxia Hui Autonomous Region, China
Received:
July 9, 2023
Revised:
September 15, 2023
Accepted:
Not specified
Published Online:
Not specified
Keywords:
Ginger, Medicine and food homology, Gastrointestinal cancer, Molecular mechanism
Scope:
Review of pharmacological effects and clinical potential of ginger on gastrointestinal tumors
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
Not specified
Region / city:
Kamuli District, Uganda
Theme:
Community development, agriculture, youth and orphan empowerment
Document type:
Project proposal
Organization:
Kwagawa Organic Farmers
Author / Contact:
Mr. Kiwole Awali, C/O P.O. Box 127 Kamuli Municipality, Uganda, Tel: 0776405799, Email: [email protected]
Project location:
Bukolobe Zone, Kasoigo Ward, Kamuli Municipality, Kamuli District, Uganda
Estimated budget:
USD 30,000
Target beneficiaries:
300 people, including youths, orphans, and women
Project objectives:
Increase household income, improve food security, create jobs, enhance health, support education for orphans
Planned outputs:
Procurement of irrigation kits, improved seeds, agrochemicals, facility training, post-harvest management
Expected outcomes:
Increased yields, reliable water supply, market opportunities, poverty alleviation, community skills development
Impact:
Food security, income growth, employment, health improvement, climate adaptation
Period:
Not specified
Date prepared:
Not specified
Year:
2023
Region / City:
Oregon
Topic:
Animal adoption, dog training
Document Type:
Adoption information
Organization:
Oregon Humane Society
Author:
Oregon Humane Society
Target Audience:
Potential dog adopters
Effective Date:
2023
Date of Changes:
N/A
Year:
2012
Region / City:
Australia
Topic:
Herbal Medicine, Diabetes
Document Type:
Research Article
Organization / Institution:
University of Sydney
Author:
Not specified
Target Audience:
Healthcare professionals, Researchers
Validity Period:
Ongoing
Approval Date:
Not specified
Amendment Date:
Not specified
Year:
2017
Region / City:
United States / Fredericksburg, VA
Topic:
Medical Equipment, Veterans Affairs
Document Type:
Sources Sought Notice
Agency / Institution:
U.S. Department of Veterans Affairs
Author:
Strategic Acquisition Center
Target Audience:
Potential Contractors
Period of Validity:
Response due by May 26, 2017
Approval Date:
May 26, 2017
Date of Changes:
N/A
Year:
2005
Region / City:
Philadelphia, PA
Topic:
Gastrointestinal Stromal Tumor (GIST), Pathology
Document Type:
Medical Procedural Guide
Organization / Institution:
Elsevier Saunders, Elsevier Churchill Livingstone
Author:
Kumar V, Abbas A, Fausto N, Lester SC
Target Audience:
Medical professionals, Pathologists
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Note:
Year
Document Type:
Lesson Plan
Target Audience:
Students
Year:
2023
Region / city:
Nanjing, P.R. China
Topic:
Biopharmacology, self-assembly, gastrointestinal environment
Document Type:
Research Article
Organization / Institution:
China Pharmaceutical University
Authors:
Yulin Mo, Yanjun Yang, Jingqi Zeng, Weikun Ma, Yuxin Guan, Jingxi Guo, Xiaochun Wu, Dingkun Liu, Liang Feng, Xiaobin Jia, Bing Yang
Target Audience:
Researchers, scientists in the field of biopharmacology
Period of validity:
N/A
Approval Date:
N/A
Date of changes:
N/A
Context:
This research paper discusses the enhancement of biopharmacological properties of Asperosaponin VI, focusing on its self-assembly transitions in the gastrointestinal environment through in vitro simulations and molecular dynamics.
Note:
Year
Contextual description:
Form used to refer patients suspected of having lower gastrointestinal cancer through a fast-track process, including details for clinical assessment and necessary tests.
Year:
2023
Region / city:
Wuhan, China
Topic:
Medical Imaging, Artificial Intelligence, Gastrointestinal Stromal Tumors
Document Type:
Research Article
Organization / Institution:
Renmin Hospital of Wuhan University
Authors:
Chenxia Zhang, Wei Tan, Xun Li, Xiao Tao, Bing Xiao, Wei Zhou, Honggang Yu
Target Audience:
Medical professionals, researchers in gastroenterology and artificial intelligence
Period of Application:
Not specified
Date of Approval:
Not specified
Date of Changes:
Not specified
Keywords:
Gastrointestinal Stromal Tumors, Endoscopic Ultrasound, Artificial Intelligence, Risk Stratification, Deep Learning
Methodology:
Image Classification, Image Segmentation, Deep Convolutional Neural Network (DCNN), ResNet, Unet++
Evaluation Metrics:
Accuracy, Intersection over Union (IoU), Precision, Recall, F1 score
Conclusion:
The use of AI-based risk stratification and image analysis improves GIST diagnosis accuracy
References:
Li J, Zhu Y, Dong Z, et al., Yao L, Zhang J, Liu J, et al., Zhou Z, Siddiquee MMR, Tajbakhsh N, Liang J
Year:
2021
Organisation:
International Collaboration on Cancer Reporting
Document type:
Histopathology reporting guide
Subject:
Gastrointestinal stromal tumour (GIST)
Scope:
Pathology reporting of resection specimens for GIST
Exclusions:
Metastatic GIST specimens
Edition:
1st edition
Applicable staging system:
Pathological TNM staging
Evidence framework:
NHMRC levels of evidence
Intended users:
Pathologists reporting GIST resection specimens
Related publications:
Gastrointestinal Stromal Tumour (GIST) Histopathology Reporting Guide – Biopsy Specimens; Soft Tissue Sarcoma Histopathology Reporting Guide – Resection Specimens
Document Type:
Supplemental figure legends
Field:
Molecular biology
Research Area:
Gastrointestinal epithelium and intestinal metaplasia
Subjects:
CDX2, HNF4A, SOX2, gastric organoids, Barrett’s esophagus, gastric intestinal metaplasia
Biological Material:
Human gastrointestinal tissues and mouse stomach organoids
Methods:
Single-cell RNA-seq, bulk RNA-seq, ATAC-seq, CUT&RUN, ChIP-seq, GSEA, enhancer analysis, immunohistochemistry, qRT-PCR
Referenced Studies:
Busslinger et al. 2021b; Nowicki-Osuch et al. 2021; Owen et al. 2018; Companioni et al. 2017; Singh et al. 2021; Gao and Kaestner 2010; Wang et al. 2013
Key Topics:
Transcriptional profiling, chromatin accessibility, enhancer activity, transcription factor binding, intestinalization of gastric epithelium
Species:
Homo sapiens; Mus musculus
Pathological Context:
Barrett’s esophagus; gastric intestinal metaplasia
Journal:
World Journal of Gastrointestinal Oncology
Manuscript Type:
Editorial
Authors:
Chang Qiao; Hao-Xiang Zhang; Xiao-Tong Tian; Yan-Jing Zhang; De-Hui Li
Co-first authors:
Chang Qiao; Hao-Xiang Zhang
Corresponding authors:
Yan-Jing Zhang; De-Hui Li
Affiliated Institutions:
Hebei University of Chinese Medicine; Guang’anmen Hospital, Academy of Chinese Medical Sciences; The First Affiliated Hospital of Hebei University of Chinese Medicine
Country:
China
Region / City:
Shijiazhuang, Hebei Province; Beijing
Research Field:
Gastrointestinal Oncology; Integrative Medicine; Multi-omics Research
Keywords:
Chinese herbal compounds; Gastrointestinal microenvironment; Chemotherapy; Multi-omics; Intestinal microecology
Funding:
Government-funded Project of the Outstanding Talents Training Program in Clinical Medicine (ZF2023165); Key Research and Development Projects of Hebei Province (18277731D); Natural Science Foundation of Hebei Province (H202423105)
Received:
September 16, 2024
Revised:
November 11, 2024
Accepted:
November 25, 2024
Published online:
February 15, 2025
DOI:
10.4251/wjgo.v17.i2.101500
Article URL:
https://www.wjgnet.com/1948-5204/full/v17/i2/101500.htm
Subject Focus:
Mechanisms of Chinese herbal compounds in mitigating chemotherapy-induced gastrointestinal injury through multi-omics approaches
Institutions Involved:
Graduate School of Hebei University of Chinese Medicine; Department of Oncology I and II, The First Affiliated Hospital of Hebei University of Chinese Medicine; Guang’anmen Hospital, Academy of Chinese Medical Sciences
Year:
2026
Region:
International
Category:
Pharmaceutical Reference
Document Type:
Medication Formulary
Active Ingredients:
Multiple (Benzoyl peroxide, Salicylic Acid, Aluminum Chloride Hexahydrate, etc.)
Dosage Forms:
Local, Oral
Trade Names:
Benzac AC, Caladerm, Cetrisam, Tussana, Imodium, etc.
Indications:
Acne, Allergy, Cold, Influenza, Cough, Diarrhea, Dyspepsia, Otic conditions
OTC Status:
Specified per ingredient (e.g., Benzoyl peroxide up to 10%, Hydrocortisone up to 1%)
Target Audience:
Healthcare professionals and pharmacists
Notes:
Includes topical gels, creams, lotions, ointments, syrups, capsules, tablets, nasal sprays, and powders
Supplementary Table S1. Baseline characteristics of gastrointestinal progressors vs. non-progressors
Year:
Not specified
Region / City:
Not specified
Theme:
Gastrointestinal disease progression
Document Type:
Table
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Researchers in gastroenterology
Period of validity:
Not specified
Approval Date:
Not specified
Date of changes:
Not specified
Date:
September 4, 2019
Patient Name:
Y.D.
Sex:
Male
Age:
41 years old
Race:
Black
Nationality:
Haitian
Marital Status:
Married
Occupation:
Police officer
Chief Complaint:
Shortness of breath
History of Present Illness:
Progressive dyspnea over 1 year with recent worsening
Past Medical History:
GERD
Past Surgical History:
None
Medications:
Docusate 100 mg BID, Pantoprazole 40 mg
Allergies:
None reported
Family History:
Non-contributory
Social History:
Denies alcohol, tobacco, caffeine, or illicit drug use; lives with wife and children
Vital Signs:
BP 134/89 mmHg, RR 18/min, P 100 bpm, T 97.5 °F, O2 Sat 90%
Physical Examination Findings:
Thin, well-nourished male, erythematous macules on neck and shoulders, decreased breath sounds on right lung, low volume left lung sounds, labored breathing, heart sounds slightly displaced
Differential Diagnosis:
Emphysema, pneumothorax, restrictive lung disease
Review of Systems:
Weight loss 15 lb in 2 months, fatigue, constipation, dysphagia, dry cough, right-sided rib pain
Functional Status:
Previously good exercise tolerance, now dyspnea at rest
Referral Source:
Self
Competency:
Competent and reliable
Source of History:
Self
Document Type:
Medical evaluation report
Intended Use:
Clinical reference for diagnostic assessment
Year:
1990s–2000s
Classification System:
ICD-9
Document Type:
Medical Reference Table
Scope:
Complications, Diagnoses, and Procedures
Audience:
Healthcare Professionals
Medical Specialties:
Pulmonology, Cardiology, Nephrology, Gastroenterology, Surgery
Data Type:
Diagnostic and Procedural Codes
Source:
International Classification of Diseases, Ninth Revision
Year:
2026
Region / city:
Not specified
Subject:
Gastrointestinal bleeding, intraoperative EGD
Document type:
Medical research paper
Organization / institution:
Not specified
Author:
Not specified
Target audience:
Medical professionals, surgeons, gastroenterologists
Period of validity:
Not specified
Approval date:
Not specified
Date of modifications:
Not specified
Year:
2021
Region / City:
Cologne, Germany
Topic:
Gastroesophageal Reflux Disease, Laryngopharyngeal Reflux, Esophageal pH Monitoring, Esophagectomy
Document Type:
Original Article
Organization:
University of Cologne, Department of General, Visceral, Cancer and Transplant Surgery
Authors:
Benjamin Babic, Dolores T Müller, Florian Gebauer, Lars Mortimer Schiffmann, Rabi R Datta, Wolfgang Schröder, Christiane J Bruns, Jessica M Leers, Hans F Fuchs
Target Audience:
Medical professionals, researchers, and clinicians in the field of gastroenterology and surgery
Period of Action:
2016-2018
Approval Date:
May 19, 2021
Revision Date:
February 11, 2021
Date Published:
June 15, 2021
Version:
1.5.0.0
Protocol Posting Date:
June 2024
CAP Laboratory Accreditation Program Protocol Required Use Date:
March 2025
Authors:
Gulisa Turashvili, MD, PhD; Uma G. Krishnamurti, MD, PhD; Barbara A. Crothers, DO; Giovanna A. Giannico, MD; Krisztina Hanley, MD; Anna Plotkin, MD; Anthony N. Karnezis, MD, PhD.
Note:
Accreditation Requirements
Date of Protocol Posting:
June 2024
Date of Required Use:
March 2025
Version:
4.2.0.0
Protocol Posting Date:
June 2024
Year:
2024
Region / city:
Not specified
Topic:
Bone tumor biopsy protocols
Document type:
Protocol
Organization / institution:
Not specified
Author:
Paari Murugan, MD, FCAP; Julie C. Fanburg-Smith, MD, FCAP; Andrew Horvai, MD, PhD; Fernanda Amary, MD, PhD; Meera Hameed, MD, FCAP; Michael J. Klein, MD
Target audience:
Clinicians and pathologists involved in biopsy procedures for bone tumors
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified