№ lp_1_2_48118
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Quantitative research data detailing LC-MS/MS measurement of tenofovir in urine and DBS samples, compared with point-of-care TFV test results and clinical adherence and viral load information.
Year: 2026
Region: Not specified
Document type: Supplementary material / Research data
Methods: LC-MS/MS, IP–HILIC–MS/MS
Analytes: Tenofovir (TFV), Tenofovir-diphosphate (TFV-DP)
Sample types: Urine, Dried Blood Spots (DBS)
Target population: Participants on antiretroviral therapy (ART)
Measured variables: Urine TFV concentration, DBS TFV-DP concentration, POC TFV results, self-reported adherence, viral load, drug resistance
Instrument: Agilent HPLC coupled to AB Sciex 5500 triple quadrupole mass spectrometer
Software: Analyst v1.6.2
Detection method: Negative-ion multiple reaction monitoring (MRM)
Tables included: S1, S2, S3, S4
Price: 8 / 10 USD
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LC-MS/MS Analysis of Serum Samples for Protein Identification and Quantification
Year: 2023
Region / City: USA
Topic: Proteomics
Document Type: Research Protocol
Author: Not specified
Target Audience: Researchers in proteomics
Date of Approval: Not specified
Date of Changes: Not specified
Clinical Commissioning Policy Tenofovir alafenamide for treatment of HIV 1 in adults and adolescents
Year: 2025
Region / City: England
Theme: HIV Treatment, Antiretroviral Therapy
Document Type: Policy Statement
Organization / Institution: NHS England
Author: NHS England
Target Audience: Healthcare professionals, policy makers
Effective Period: Ongoing from May 2025
Approval Date: May 2025
Date of Last Update: August 2025
Clinical Commissioning Policy for Tenofovir Alafenamide in the Treatment of HIV-1 in Adults and Adolescents
Year: 2021
Region: England
Subject: HIV-1 treatment
Document type: Clinical commissioning policy
Organization: NHS England
Target audience: Adults and adolescents living with HIV-1
Approved date: 2021
Drug reviewed: Tenofovir alafenamide (TAF)
Treatment context: Antiretroviral therapy (ART)
Purpose: Funding and clinical guidance for TAF use
Evidence reviewed: Comparative safety and efficacy versus TDF
Population: Patients with contraindications to TDF or with complications during treatment
Tenofovir alafenamide, TABLET 25 MG, VEMLIDY®, GILEAD SCIENCES
Year: 2017
Region / city: Australia
Subject: Chronic Hepatitis B, Antiviral Therapy
Document Type: Submission for PBS listing
Agency / institution: PBAC (Pharmaceutical Benefits Advisory Committee)
Author: GILEAD SCIENCES
Target audience: Healthcare professionals, policymakers
Period of validity: Not specified
Approval date: 22 February 2017
Amendment date: Not specified
Information for patients switching from Atripla® to generic tenofovir, emtricitabine and efavirenz
Year: 2018
Region / city: United Kingdom, Ireland
Subject: Medicine information
Document type: Patient information leaflet
Organization: HIV Pharmacy Association (HIVPA)
Author: HIV Pharmacy Association (HIVPA)
Target audience: Patients switching from Atripla to generic tenofovir, emtricitabine, and efavirenz
Effective period: From February 2018
Approval date: February 2018
Date of changes: Not mentioned
Contact: Telephone number: [Provided in document]
Topics: TFV LC-MSMS Tenofovir