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The document is a research article focusing on the proteomic analysis of hypertension-related albuminuria in a South African cohort, utilizing machine learning to identify biomarkers associated with immune and extracellular matrix systems.
Year: 2023
Region / City: South Africa, Johannesburg, Pretoria
Topic: Hypertension, Albuminuria, Proteomics
Document Type: Research Article
Institution: University of the Witwatersrand, Council for Scientific and Industrial Research
Author: Melanie A. Govender, Stoyan H. Stoychev, Jean-Tristan Brandenburg, Michèle Ramsay, June Fabian, Ireshyn S. Govender
Target Audience: Researchers in Molecular Biology, Clinical Medicine
Date of Approval: Not specified
Date of Changes: Not specified
Methodology: Machine Learning, Protein Quantification
Keywords: Hypertension, Albuminuria, Proteomics, Immune System, Extracellular Matrix, Machine Learning, South African Cohort
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Proteomic Analysis of Haptenation by Skin Sensitisers Diphencyprone and Ethyl Acrylate
Authors: Erika Parkinson; Maja Aleksic; Rachael Arthur; Sergio Regufe Da Mota; Richard Cubberley; Paul J. Skipp
Corresponding author: Paul Skipp, Ph.D.
Affiliations: Biological Sciences, University of Southampton; Centre for Proteomic Research, Institute for Life Sciences, University of Southampton; Safety & Environmental Assurance Centre, Unilever, Colworth Science Park
Region: Southampton, UK; Sharnbrook, UK
Thematic area: Proteomics; Skin sensitisation; Allergic contact dermatitis; Chemical toxicology
Keywords: allergic contact dermatitis; Diphencyprone; Ethyl Acrylate; HSA; MSE; proteomics; sensitization; skin
Abbreviations: Diphenylcyclopropenone (DPCP); Diphencyprone; Ethyl Acrylate (EA); Human Serum Albumin (HSA); HaCaT
Type of document: Scientific research article
Subject of study: Protein haptenation in HSA and HaCaT cell lysates induced by DPCP and EA
Methodology: Stable isotope labelling combined with data-independent acquisition mass spectrometry (HDMSE/DIA)
Institutional context: Academic and industry collaboration
Contact information: Tel +44 (0)2380 594204; Fax +44 (0)2380 594459; Email [email protected]
Organelle isolation from Mouse Embryonic Fibroblasts (MEFs) stably expressing organelle tags for subsequent immunoblotting or proteomic analysis
Year: 2023
Region / city: Not specified
Subject: Organelle isolation, immunoblotting, proteomic analysis
Document type: Scientific protocol
Organization / institution: Not specified
Author: Matthew Taylor, Pui Yiu Lam, Francesca Tonelli, Dario Alessi
Target audience: Researchers in molecular biology, cell biology, and proteomics
Period of validity: Not specified
Date of approval: Not specified
Date of amendments: Not specified
Proteomic analysis of synovial fluid: current and potential uses to improve clinical outcomes
Year: 2018
Region / Institution: University of Liverpool, Institute of Ageing and Chronic Disease
Subject: Proteomics, Synovial Fluid, Arthropathies
Document Type: Review Article
Authors: Mandy Jayne Peffers, Aibek Smagul, James Ross Anderson
Target Audience: Researchers and clinicians in musculoskeletal and rheumatologic fields
Methods Discussed: Mass spectrometry, protein fractionation, immunoaffinity depletion, ultrafiltration
Diseases Covered: Osteoarthritis, Rheumatoid Arthritis, Juvenile Arthritis, Spondyloarthritis
Data Sources: PubMed, 1991–2018
Correspondence: [email protected]
Telephone: 07872692102
Topics: hypertension-associated albuminuria Proteomic