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PhD research project proposal detailing a study on microbial genomics and enzyme discovery aimed at identifying and engineering cryptic biosynthetic gene clusters for novel natural products.
Research Theme:
Microbiology; Synthetic biology
PhD Research Project Title:
Genome-guided discovery of novel microbial enzymes and natural products
Scholarship category:
SBS Research Student Scholarship
Principal Investigator:
Liang Zhao-Xun
Co-supervisor/Collaborator:
NA
Proposed work:
Microbial genomics, Bioinformatics, Enzyme discovery, Functional characterization, Genetic manipulation, Synthetic biology
Preferred skills:
Basic understanding of biochemistry and molecular cloning
Application contact:
[email protected]
Application portal:
https://venus.wis.ntu.edu.sg/GOAL/OnlineApplicationModule/frmOnlineApplication.ASPX
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2023
Region / city:
European Union
Subject:
Food additives, food enzymes, food flavourings
Document type:
Practical guidance
Organization / institution:
European Commission, DG SANTE
Author:
European Commission
Target audience:
Applicants for updating Union lists of food additives, food enzymes, and food flavourings
Effective period:
Ongoing
Approval date:
7 July 2023
Date of changes:
7 July 2023
Year:
2014
Discipline:
Plant biology; biochemistry; molecular biology
Document type:
Classroom case study and assignment
Authors:
Brian Sullivan; Shuchismita Dutta
Affiliations:
Department of Plant and Microbial Biology, North Carolina State University, Raleigh NJ 27695; Institute for Quantitative Biomedicine, Rutgers University, Piscataway NJ 08854
Contact author:
[email protected]
Related publications:
Science, 2014, 345, 1181–1184; The New York Times, September 2014
Key topics:
Caffeine biosynthesis; N-methyltransferases; allelopathy; enzyme structure; Protein Data Bank
Referenced organisms:
Coffee plant; tea plant; cocoa plant; mate plant
Referenced resources:
DrugBank; RCSB Protein Data Bank
Educational context:
Pre-class preparation and in-class discussion
Year:
2026
Region / city:
Deep-sea vent habitats
Subject:
Functional analysis of N-linked glycosylation systems
Document type:
Research article
Organization / institution:
London School of Hygiene and Tropical Medicine, University of Manchester, Cornell University
Author:
Dominic C Mills, Adrian J Jervis, Sherif Abouelhadid, Laura E Yates, Jon Cuccui, Dennis Linton, Brendan W Wren
Target audience:
Researchers in biochemistry and microbiology
Period of validity:
Ongoing research
Approval date:
N/A
Modification date:
N/A
Note:
Year
Year:
2022
Region / City:
Barcelona, Spain
Topic:
Genetic Engineering, Enzymes, Environment
Document Type:
Research Report
Organization:
FHNW, BSC, CSIC
Author:
Víctor Guallar, Manuel Ferrer
Target Audience:
Researchers, Environmental Scientists, Industry Professionals
Action Period:
From 01/08/2021
Date of Approval:
30/09/2022
Modification Date:
N/A
Work Package:
WP5, Enhancing enzymes through innovative engineering
Duration:
40 months
Lead Beneficiary:
FHNW
Participants:
FHNW, CSIC, BSC, Bangor, UHAM, UDUS, Inofea AG, Eucodis
Contact:
Víctor Guallar, [email protected]
Year:
2023
Region / City:
Los Angeles, NJ
Topic:
Biochemistry, Molecular Biology
Document Type:
Educational Lesson
Organization / Institution:
Los Angeles Mission College, Rutgers University
Author:
Brian Gadd, Shuchismita Dutta
Target Audience:
Students in molecular biology, biochemistry, or related fields
Period of Validity:
Ongoing
Approval Date:
N/A
Modification Date:
N/A
Year:
2026
Subject:
Biology / Biochemistry
Document Type:
Laboratory Manual
Institution:
OpenStax / Educational Laboratory
Audience:
Undergraduate Biology Students
Experiment:
Catalase Activity under Various Conditions
Techniques:
Spectrophotometry, Graph Construction, Experimental Design
Learning Objectives:
Define enzyme properties, analyze activity under conditions, conduct experiments, interpret data, report results
Year:
2026
Region / City:
Not specified
Topic:
Bariatric surgery, liver enzymes
Document type:
Research Supplementary Material
Institution:
Not specified
Author:
Not specified
Target audience:
Researchers, medical professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Context:
A supplementary table providing quantification and allocation of inclusion indicators for abnormal elevation of liver enzymes in patients post-bariatric surgery.
Year:
2025
Region / City:
Nauni, Solan (H.P.)
Topic:
Microbial Enzyme Activity in Compost
Document Type:
Research Article
Organization / Institution:
Dr. Y.S. Parmar University of Horticulture and Forestry
Author:
Not specified
Target Audience:
Agricultural researchers, mushroom farmers
Period of Activity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2015
Region / City:
Zaria, Nigeria
Topic:
Biochemical effects of L- Ascorbic acid and α –Tocopherol on insulin resistance and lipid profile
Document Type:
Research Article
Institution:
Ahmadu Bello University, Usmanu Danfodiyo University
Author:
Y. Tanko, T.S Olaleye, K.A. Mohammed, A. Jimoh, M.A. Dewu, M.K. Dallatu, M. Yerima, A. Mohammed
Target Audience:
Researchers, Health Professionals
Period of Action:
2015
Date of Approval:
2015
Date of Modifications:
N/A
Keywords:
L- Ascorbic acid, α –Tocopherol, High fat diet, Liver enzymes, Lipid profile
Note:
Contextual Description
Year:
2026
Subject:
Biochemistry
Document Type:
Study Guide
Institution:
Academic / Educational Resource
Target Audience:
Undergraduate and graduate students in biology or related fields
Topics Covered:
Enzyme structure and function, metabolic pathways, enzyme inhibition, thermoregulation, reaction kinetics
Key Concepts:
Active site, induced-fit model, competitive and non-competitive inhibition, anabolism, catabolism, intracellular and extracellular reactions, energy transformations
Format:
Text-based educational briefing with diagrams and quizzes
Application:
Laboratory and theoretical exercises in enzymology and metabolism
Year:
2023
Region / city:
Antarctica, Arctic, Tropics
Subject:
Microbiology, Soil Science, Environmental Science
Document type:
Research Article
Organization / Institution:
National Antarctic Research Centre, University Malaya, British Antarctic Survey, Instituto Antártico Chileno, Institute of Nature Conservation Polish Academy of Sciences
Author:
Abiramy Krishnan, Peter Convey, Marcelo Gonzalez, Jerzy Smykla, Siti Aisyah Alias
Target Audience:
Researchers in Microbiology, Environmental Science, Soil Ecology
Period of Activity:
2007–2014
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2026
Subject:
Biochemistry
Topic:
Enzyme inhibition and immobilized enzymes
Document type:
Worksheet answer key
Audience:
Students
Institution:
Educational / Academic
Marks allocation:
19 marks
Temperature conditions discussed:
25–55°C
Key chemicals mentioned:
Malonate, succinate, lactase
Assessment focus:
Competitive and non-competitive inhibition, effects of pH and temperature, enzyme reuse
Year:
2013
Subject:
Enzymes
Topic:
Enzyme structure and reaction rate
Type of document:
Revision worksheet and marking guide
Educational level:
Secondary science
Assessment type:
Short-answer questions
Total marks:
10
Concepts covered:
Lock and key model; enzyme–substrate complex; active site; temperature and reaction rate; activation energy
Source reference:
hi.com.au science resource image 12694
Language:
English
Year:
2026
Region / State:
Kentucky, USA
Subject:
Animal feed labeling
Document Type:
Regulatory guidance
Issuing Authority:
Kentucky Department of Agriculture
Reference Standards:
AAFCO Official Publication, 12KAR 2:041, 12KAR 2:018
Target Audience:
Feed manufacturers and pet food producers
Required Guarantees:
Direct fed microbials, viable yeasts, enzymes
Ingredient Listing:
Order of predominance by weight
Analysis Units:
Colony Forming Units (CFU) for microbes, enzymatic activity units for enzymes
Compliance Notes:
Pet and specialty pet products must follow additional labeling requirements including disclaimers for non-essential nutrients
Course Code:
MCB 424
Term:
Spring 2024
Credits:
3 Credit Hours
Instructor:
William Metcalf
Instructor Email:
[email protected]
Instructor Office:
B415 CLSL
Instructor Office Hours:
Mondays 4:00 – 5:00 PM, or by appointment
Teaching Assistant:
Divyanshi
TA Email:
[email protected]
TA Office:
Learning Center, Burrill Hall
TA Office Hours:
Wednesdays 8:50 – 9:50, or by appointment
Class Schedule:
Monday, Wednesday, Friday 10:00 – 10:50 PM
Classroom:
140 Burrill Hall
Prerequisites:
MCB 250 and MCB 354 or MCB 450, or consent of instructor
Course Text:
The physiology and biochemistry of prokaryotes by David White
Other Texts:
Biology of the Prokaryotes, Bacterial Metabolism
Course Website:
http://www.life.illinois.edu/mcb/424
Grading:
Option I (400 points) or Option II (600 points)
Assessments:
3 Exams, 6 Problem Sets, 1 Quiz, Muddiest Points, Final Exam (optional)
Problem Set Deadlines:
February 2, February 14, March 6, March 26, April 10, April 26
Exams:
February 16, March 27, April 29
Optional Final Exam:
May 10, 1:30–4:30 PM
Policies:
MCB Curriculum Policies, Religious Observances, Late Add, Contacting Course Personnel
Learning Outcomes:
Understanding microbial metabolism, energy conservation, adaptation to environments, predicting metabolic pathways
Target Audience:
Undergraduate students in Molecular & Cellular Biology
Year:
2023
Region / city:
Northern Arizona
Subject:
Genetics, Microbial Research
Document Type:
Protocol
Institution:
Northern Arizona University, College of Engineering, Forestry and Natural Sciences, School of Forestry and Center for Microbial Genetics and Genomics
Author:
Northern Arizona University
Target Audience:
Researchers in microbial genetics, field biologists
Period of validity:
N/A
Approval Date:
N/A
Modification Date:
N/A
Context:
Protocol for collecting guano samples for genetic analysis, detailing materials and procedures for field sampling and preservation.
Year:
2021
Region / City:
Hainan, China
Subject:
Microbial ecology, agriculture
Document Type:
Research Article
Organization / Institution:
Hainan University
Author:
Manman Zhang, Rui Wang, Raja Asad Ali Khan, Xin Zhan, Sen Ren, Haonan Jiang, Yinggu Wu, Fanxing Yang, Xiaoli Yu, Tong Liu
Target Audience:
Researchers, Agricultural Scientists
Period of Effect:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Advertised Job Title:
Postdoctoral Fellowship – Microbial Ecology of Coastal Environments
Reference Number:
43884
Classification:
CSOF4
Salary Range:
AU $80K to AU $91K plus up to 15.4% superannuation
Location:
Clayton, Victoria Australia
Tenure:
Specified Term of 3 years
Relocation assistance:
Provided to the successful candidate if required
Applications are open to:
All Candidates
Functional Area:
Research Scientist / Engineer - Postdoc
Reports to:
Team Leader Environmental Genomics
Number of Direct Reports:
0
Organisational Unit:
Environmental Genomics Team, CSIRO Oceans and Atmosphere
Organisation:
CSIRO
Field of Research:
Microbial Ecology, Environmental Genomics, Marine Biogeochemistry
Project Focus:
Microbial community composition and biogeochemical processes in estuarine sediments
Key Responsibilities:
Independent research, field sampling, molecular analyses, data analysis, publication and conference presentation
Required Qualification:
PhD in a relevant discipline such as Microbial/Molecular Ecology
Experience Requirement:
Maximum 3 years relevant postdoctoral experience
Employment Type:
Full-time Postdoctoral Fellowship
Training Program:
CSIRO Postdoctoral Training Program including discipline-specific techniques, professional development, project management and communication skills
Year:
2019
Region / city:
Wendelsheim, Germany
Topic:
Celiac disease, food additives, microbial transglutaminase
Document type:
Letter to the editor
Organization / institution:
AESKU.KIPP Institute
Authors:
Aaron Lerner, Torsten Matthias
Target audience:
Researchers, healthcare professionals
Period of validity:
Not specified
Approval date:
October 15, 2019
Modification date:
October 9, 2019