№ files_lp_4_process_3_128964
Randomized clinical study on adolescent girls showing that dietary supplementation with soluble corn fiber increases calcium absorption and alters gut microbiome composition, with measurements of bone biomarkers and fecal microbial profiles.
Year: 2012–2013
Region / City: United States, West Lafayette, IN and Phoenix, AZ
Topic: Nutrition, Bone Health, Microbiome
Document Type: Research Article
Institution: Arizona State University, Purdue University
Authors: Corrie M Whisner, Berdine R Martin, Cindy H Nakatsu, Jon A Story, Claire J MacDonald-Clarke, Linda D McCabe, George P McCabe, Connie M Weaver
Target Audience: Adolescent females
Study Design: Randomized, double-blind, cross-over, dose-response trial
Intervention: Soluble corn fiber (SCF) supplementation at 0, 10, 20 g/d
Primary Outcome: Calcium absorption efficiency
Secondary Outcomes: Fecal microbial composition, short chain fatty acid production, fecal pH
Support: Tate & Lyle Ingredients Americas LLC
Conflicts of Interest: Connie M Weaver is Advisory Board Member for Pharmavite; other authors declared no conflicts
Clinical Trial Registration: Clinicaltrials.gov NCT01660503
Figures: 5
Tables: 4
Price: 8 / 10 USD
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