№ files_lp_3_process_7_000054
Institutional press release reporting the identification, structural characterization, and functional analysis of the Golgi cation channel GolpHCat and its link to hippocampus-dependent memory impairment in mice.
Document Type: Press Release
Organization: Institute for Basic Science (IBS)
Center: Center for Cognition and Sociality; Center for Biomolecular and Cellular Structure
Paper Title: GolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory
Journal: Nature Communications
Publication Date: 2024-07-11
DOI: 10.1038/s41467-024-49297-8
Authors: Hyunji Kang; Ah-reum Han; Aihua Zhang; Heejin Jeong; Wuhyun Koh; Jung Moo Lee; Hayeon Lee; Hee Young Jo; Miguel A. Maria-Solano; Mridula Bhalla; Jea Kwon; Woo Suk Roh; Jimin Yang; Hyun Joo An; Sun Choi; Ho Min Kim; C. Justin Lee
Contact: William I. Suh ([email protected]
Note: )
Research Field: Neurobiology; Structural Biology; Molecular Dynamics; Glycomics
Main Subject: Identification, structural analysis, and physiological role of GolpHCat in Golgi pH regulation and memory
Collaborating Institutions: Ewha Womans University College of Pharmacy; Chungnam National University Department of Analytical Science and Technology
Funding Bodies: Ministry of Science and ICT; National Research Foundation of Korea
Related Model: GolpHCat knockout mice
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