№ files_lp_4_process_1_34463
File format: docx Character count: 9801 File size: 1723 KB
Year: 2026
Research Institution: Unspecified biomedical research laboratory
Type of Document: Supplementary data for a scientific study
Subject: NK-92 cell cytotoxicity, CA9, NHE1, gene expression profiling
Organism / Cell Line: Human melanoma cell lines WM3629, WM1727A, WM4237; NK-92 and NK-92MI cells
Methods: In vitro cytotoxicity assays, immunoblotting, confocal microscopy, mRNA sequencing
Key Genes / Proteins: CA9, NHE1, c-Myc, SCO2, ITGB1P1, TRIM9, SVIL, KDM5B, S100A8, NTRK2, SMAD3, MYO1E, FMNL2, GABRB3, RBM41, P2RX5, PDGFRL
Experimental Conditions: pH-controlled media, empty vector controls, constitutively active NHE1, NHE1-E262I mutant
Data Type: Figures S1–S5, Tables S1–S2
Statistical Analysis: Two-way ANOVA, unpaired t-test
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