№ files_lp_4_process_3_071569
Report of a clinical case describing the development, diagnosis, surgical treatment, and progression of diffuse invasive signet ring cell carcinoma in the colorectum of a young woman with a history of ulcerative colitis.
Year: 2021
Region / City: Beijing, China
Topic: Colorectal cancer, Ulcerative colitis
Document type: Case report
Authors: Zhi Zhang, Peng-Fei Yu, Guo-Li Gu, Yu-Hui Zhang, Yu-Ming Wang, Zhi-Wei Dong, Hai-Rui Yang
Corresponding author: Guo-Li Gu
Patient age: 31 years
Diagnosis: Diffuse invasive signet ring cell carcinoma of colorectum
Treatment: Laparoscopic total colorectal resection, ileal pouch–anal anastomosis, ileostomy, FOLFOX + cetuximab chemotherapy
Outcome: Patient deceased after 7 months due to tumor progression and multiple organ dysfunction
Funding: Beijing Capital Medical Development Research Fund, No. Shoufa2020-2-5122
Keywords: Ulcerative colitis; Colorectal cancer; Signet ring cell carcinoma; Case report
Clinical presentation: Mucopurulent bloody stools, abdominal distension
Histopathology: Rectal mucinous adenocarcinoma, confirmed SRCC
Genetic testing: Tumor mutational burden 26.2/Mb
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