№ files_lp_4_process_3_103473
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Observational study analyzing microRNA and serum VEGF levels as non-invasive biomarkers in HCV-infected patients to monitor progression to cirrhosis and hepatocellular carcinoma.
Year:
2026
Region / City:
Egypt, Benha
Subject:
Hepatitis C, Hepatocellular carcinoma, Biomarkers
Document Type:
Research Article
Institution:
Benha University, Faculty of Medicine
Departments:
Medical Microbiology and Immunology; Hepatology, Gastroenterology and Infectious Diseases
Authors:
Amal M. Matta, Reem R. Abd El-Galil, Hala A. Tabl, Heba-Allah F. El-Marakby, Ahmed S. Elgazar
Ethical Approval:
Benha University Academic and Ethical Committee
Participants:
90 (32 CHC, 23 CHC with liver cirrhosis, 20 CHC with HCC, 15 healthy controls)
Methods:
Real-time PCR for miR-34a, ELISA for VEGF
Data Collection Period:
Not specified
Key Findings:
miR-34a downregulated in HCV patients with HCC and cirrhosis; VEGF levels elevated in disease progression
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Year:
2023
Region / city:
Not specified
Topic:
Ophthalmology, Medical Drugs
Document Type:
Medical Authorization Form
Organization / Institution:
Not specified
Author:
Not specified
Target audience:
Healthcare Providers
Effective period:
Not specified
Approval date:
Not specified
Amendment date:
Not specified
Context:
Medical request form for prior authorization of ophthalmic VEGF inhibitors, detailing drug choices and criteria for approval.
Year:
2023
Region / City:
Indianapolis, IN
Topic:
Periodontal Regeneration
Document Type:
Research Article
Institution:
Indiana University School of Dentistry
Authors:
Raziel Velgis, L. Jack Windsor, Vanchit John, Chandni Batra
Target Audience:
Researchers, Dental Professionals
Period of Validity:
N/A
Approval Date:
N/A
Modification Date:
N/A
Keywords:
rhPDGF-BB, VEGF, Periodontal Ligament Cells, Proliferation, Regeneration
Context:
A research article investigating the effects of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) on the proliferation of periodontal ligament cells and VEGF expression.
Year:
2026
Region / City:
Germany
Topic:
Analytical Chemistry, Isotope Dilution, Mass Spectrometry
Document Type:
Scientific Paper
Organization / Institution:
Roche Diagnostics GmbH
Author:
Lea Lewina, Michael Stadlmeier, Neeraj Singh, Friederike Bauland, Daniel Köppl, Alexander Gaudl, Andrea Geistanger, Uta Ceglarek, Manfred Rauch, Judith Taibon
Target Audience:
Researchers in analytical chemistry, medical diagnostics, and pharmaceutical sciences
Period of Validity:
Not specified
Date of Approval:
Not specified
Date of Revision:
Not specified
Year:
Not specified
Region / City:
India
Topic:
Angiogenic factors, Pregnancy complications, Fetal death
Document Type:
Research Data / Supplementary Table
Organization:
Not specified
Author:
Not specified
Target Audience:
Researchers, Medical professionals
Period of validity:
Not specified
Approval Date:
Not specified
Date of changes:
Not specified
Year:
2021
Region / city:
Penzberg, Essen, Erlangen, Leipzig
Topic:
Analytical chemistry, steroid profiling
Document type:
Reference measurement procedure
Institution:
Roche Diagnostics GmbH
Author:
Lea Lewin, Michael Stadlmeier, Neeraj Singh, Friederike Bauland, Daniel Köppl, Alexander Gaudl, Andrea Geistanger, Uta Ceglarek, Manfred Rauh, Judith Taibon
Target audience:
Laboratory technicians, medical researchers, clinicians
Period of validity:
Ongoing
Approval date:
Not specified
Date of changes:
Not specified
Year:
Not specified
Region / city:
Not specified
Subject:
Serum protein binding, small proteins
Document type:
Protocol
Organization / institution:
Not specified
Author:
Not specified
Target audience:
Researchers, scientists
Effective period:
Not specified
Approval date:
Not specified
Modification date:
Not specified
Journal:
World Journal of Gastrointestinal Pathophysiology
Manuscript Type:
Original Article
Study Design:
Retrospective Cohort Study
Authors:
Hyun Ah Chung; Sun-Young Lee; Hee Won Moon; Jeong Hwan Kim; In-Kyung Sung; Hyung Seok Park; Chan Sup Shim; Hye Seung Han
Affiliations:
Department of Internal Medicine, Department of Laboratory Medicine, and Department of Pathology, Konkuk University School of Medicine, Seoul 05030, South Korea
Corresponding Author:
Sun-Young Lee, MD, PhD
Country:
South Korea
Funding:
Supported by Konkuk University in 2015 (No. KU2015-A019-0270)
Institutional Review Board Approval:
Konkuk University School of Medicine (KUH1010625)
Clinical Trial Registration:
ClinicalTrials.gov ID: KCT0001302
Received:
December 27, 2015
Accepted:
July 11, 2016
Publication Year:
2016
Keywords:
Antibody; Helicobacter pylori; Hepatitis B; Immunoglobulin G; Pepsinogen
License:
Creative Commons Attribution Non Commercial (CC BY-NC 4.0)
Year:
2021
Region / City:
N/A
Topic:
Psychosocial Stress, Oxidative Stress, Biochemical Analysis
Document Type:
Research Supplement
Organization / Institution:
University of Maryland
Author:
Eunkyoung Kim, Zhiling Zhao, John Robertson Rzasa, Matthew Glassman, William E. Bentley, Shuo Chen, Deanna L. Kelly, Gregory F. Payne
Target Audience:
Researchers, Medical Professionals
Period of Validity:
N/A
Approval Date:
N/A
Date of Modifications:
N/A
Note:
Year
Topic:
Calibration of serum creatinine
Document Type:
Supplementary Table
Organization / Institution:
CDC
Target Audience:
Healthcare professionals, researchers in epidemiology and kidney disease
Context:
Supplemental tables with demographic data and creatinine calibration equations across multiple NHANES survey periods for U.S. adults.
Year:
2025
Region / city:
N/A
Topic:
Clinical research
Document type:
Scientific article
Organization:
N/A
Author:
Stefanska A, Krintus M, Siodmiak J, Wolska A, Szternel L, Gackowska L, et al.
Target audience:
Researchers, healthcare professionals
Period of validity:
N/A
Approval date:
N/A
Date of changes:
N/A
Year:
N/A
Region / City:
N/A
Subject:
Biochemical Analysis
Document Type:
Methodology
Institution:
N/A
Author:
N/A
Target Audience:
Laboratory technicians, researchers
Period of Use:
N/A
Approval Date:
N/A
Date of Revision:
N/A
This document describes a biochemical method for measuring ALT (SGPT) activity in serum samples using two different assay techniques:
discontinuous (colorimetric) and continuous (UV/kinetic).
Note:
Year
Document Type:
Laboratory protocol
Target Audience:
Researchers, laboratory technicians
Authors:
Yan Xu; Yong-Li Dai; Hong Lei; Ying-Lun Yuan; Tian-Le Hu; Xia Wei; Lin-Mei Guo; Yong-Mei Lan
Corresponding Authors:
Lin-Mei Guo; Yong-Mei Lan
Study Period:
November 2024–March 2025
Location:
Lanzhou, Gansu, China
Type of Document:
Original research article
Field:
Paediatric medicine; Microbiology; Clinical immunology
Study Population:
Children aged 3–14 years
Sample Size:
90 participants (30 MPP; 30 NMP; 30 healthy controls)
Methods:
16S rRNA sequencing; serum trace element detection; clinical laboratory analysis
Ethics Approval:
Approved by hospital ethics committee (2024KY22213)
Keywords:
16S rRNA; children; iron; intestinal flora; Mycoplasma pneumoniae pneumonia; zinc
Year:
2011-2019
Region / city:
Not specified
Subject:
Medical research, Serum magnesium levels
Document type:
Research table
Institution:
Not specified
Author:
Not specified
Target audience:
Researchers, Medical professionals
Period of action:
Not specified
Approval date:
Not specified
Modification date:
Not specified
Context:
The document presents the results of a univariate Cox regression analysis related to serum magnesium levels and in-hospital mortality.
Year:
2026
Region / City:
Not specified
Subject:
Clinical diagnostics, virology
Document Type:
In vitro diagnostic test instructions
Organization:
ZEUS Scientific, Inc.
Author:
Not specified
Target Audience:
Laboratory personnel
Period of Use:
Ongoing
Date of Issue:
2026
Safety Precautions:
Biosafety Level 2, toxic and irritant reagents handling instructions included
Components:
Microplate strips, conjugate, controls, calibrator, diluent, substrate, stop solution, wash buffer
Intended Sample:
Human serum
Test Principle:
ELISA detection of IgG antibodies to EBV Nuclear Antigen 1 (EBNA-1)
Assay Procedure:
Three-step incubation with antigen-coated wells, conjugate, and substrate followed by photometric measurement
Year:
2026
Type of document:
Product datasheet
Intended use:
Research use only
Assay type:
Competitive ELISA
Sample type:
Human and animal urine, serum, and tissue
Format:
96-well microtiter plate
Storage conditions:
4 - 10°C, do not freeze
Expiry:
12 months from manufacturing date
Manufacturer:
Not specified
References:
9 scientific publications cited
Year:
2017-2018
Region / City:
Tanda at Kangra, India
Field:
Urology
Document Type:
Research Article
Institution:
Dr. Rajender Prasad Government Medical College, Tanda at Kangra, India
Author:
Angesh Thakur, Uttam K. Mehta, Monika Thakur, Ritu Aggarwal
Target Audience:
Medical professionals, researchers in urology and immunology
Period of Study:
January 2017 - June 2018
Date of Submission:
Not specified
Keywords:
Renal cell carcinoma, interleukin-6, nephron sparing surgery, nephrectomy, minimally invasive surgery
Acknowledgement:
No specific grant support received
Conflict of Interest:
None reported