№ files_lp_4_process_3_108832
Prospective cohort study examining associations between maternal plasma B12, folate, and homocysteine levels during pregnancy and subsequent neuro-endocrine and cardiovascular stress responses in adolescent offspring during the Trier Social Stress Test for Children.
Year: 1997-1998
Region / city: Mysore, India
Research unit: Epidemiology Research Unit, CSI Holdsworth Memorial Hospital; MRC Lifecourse Epidemiology Unit, Southampton General Hospital; Department of Paediatrics, University of Oxford; Diabetes Unit, King Edward Memorial Hospital and Research Center
Authors: GV Krishnaveni, SR Veena, M Johnson, K Kumaran, A Jones, DS Bhat, CS Yajnik, CHD Fall
Keywords: B12 deficiency, folate, homocysteine, stress response, cortisol, adolescent
Funding: Parthenon Trust, Switzerland; Wellcome Trust, UK; Medical Research Council, UK; Department for International Development, UK; Wellcome Trust-DBT India Alliance
Correspondence: [email protected]
Study type: Prospective cohort study
Population: Pregnant women and their adolescent offspring
Sample size: 830 mothers recruited, 264 adolescents completed TSST-C
Measurements: Maternal plasma B12, folate, homocysteine; offspring salivary cortisol; heart rate; blood pressure; stroke volume; cardiac output; total peripheral resistance
Objective: Examine associations between maternal one-carbon nutrients and offspring stress responses
Period of follow-up: From pregnancy to 13.5 years of age
Price: 8 / 10 USD
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