№ lp_1_2_25111
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This document summarizes decisions and recommendations made by the HNY APC regarding drug formularies, treatment protocols, and guidelines for NHS healthcare professionals.
Year:
2025
Region / City:
Humber and North Yorkshire
Subject:
Pharmaceutical guidelines, drug and treatment protocols
Document Type:
Decision summary
Organization:
HNY APC (Humber and North Yorkshire Area Prescribing Committee)
Author:
HNY APC
Target Audience:
NHS Healthcare Professionals
Approval Date:
2nd July 2025
Date of Changes:
June 2025
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Year:
2025
Region / City:
Humber and North Yorkshire
Theme:
Medicines Optimisation, Pharmaceutical Services
Document Type:
Meeting Minutes
Organisation:
Humber and North Yorkshire Integrated Care Board (NHS HNY ICB)
Author:
Laura Angus (Chair)
Target Audience:
Healthcare professionals, pharmacists, healthcare managers
Period of Validity:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Year:
2025
Region / City:
Humber and North Yorkshire
Topic:
Clinical and Pharmaceutical Policy
Document Type:
Meeting Minutes
Organ / Institution:
Humber and North Yorkshire ICB
Author:
Nigel Wells
Target Audience:
Health professionals, pharmacists, healthcare administrators
Period of Action:
January 2025
Approval Date:
8th January 2025
Date of Modifications:
N/A
Year:
2024/25
Region / City:
Not specified
Topic:
Continuing Professional Development (CPD) for Dyslexia Guild Members
Document Type:
Membership Requirement Guidelines
Organization:
The Dyslexia Guild
Author:
Not specified
Target Audience:
Members of The Dyslexia Guild, APC holders
Period of validity:
Annual CPD requirement
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2025
Month:
November
Region:
Humber and North Yorkshire
Country:
United Kingdom
Document type:
Committee decision summary
Organisation:
Humber and North Yorkshire Area Prescribing Committee (HNY APC)
Approved by:
HNY APC
Date of approval:
3 December 2025
Reviewed by:
CPC
Scheduled review:
January meeting
Legal framework:
NICE technology appraisals implementation within NHS
Scope:
Medicines commissioning, formulary status, shared care protocols
Intended audience:
NHS healthcare professionals
Contact organisation:
HNY APC Professional Secretariat, Regional Drug and Therapeutics Centre, Newcastle upon Tyne
Usage restriction:
Not for commercial or marketing purposes
Year:
2021
Study:
Global Burden of Disease Study 2021 (GBD 2021)
Topic:
Epidemiological modeling and data sources for COPD incidence and mortality
Document type:
Technical nomenclature and methodological description
Field:
Epidemiology and public health
Model:
Age–Period–Cohort (APC) model
Data source system:
Global Health Data Exchange (GHDx)
Database:
Causes of Death (CoD) database
Modeling tools:
DisMod-MR; MR-BRT (Bayesian regularized model with temporal smoothing)
Geographic coverage:
204 countries and territories
Health condition:
Chronic Obstructive Pulmonary Disease (COPD)
Data source types:
surveys, censuses, vital registration, surveillance systems, cancer registries, police records, sibling history, survey/census data, minimally invasive tissue sample diagnoses
Reference parameters:
reference age group (a0), reference period (p0), reference cohort (c0)
Statistical measures:
Net Drift, Age Deviations, Period Deviations, Cohort Deviations, Longitudinal Age Curve, Period Rate Ratios, Cohort Rate Ratios, Local Drifts
Data access platform:
Global Health Data Exchange citation tool
File format available:
CSV metadata export
Outlier criteria:
exclusion of implausible values, conflicts with age or temporal patterns, and inconsistencies with comparable data sources
Year:
2013
Region / City:
Waterloo
Topic:
Mechanical testing of sheet materials
Document Type:
Meeting Agenda
Organization:
Novelis, CANMET, Amino
Author:
Unknown
Target Audience:
Project partners
Effective Period:
October 4, 2013
Approval Date:
October 4, 2013
Date of Changes:
Not mentioned
Note:
Summary of the document
Version:
HNY v3.0
Replaces version:
HNY v2.0
Clinical content last reviewed:
November 2023
Next review date:
July 2028
Local approval:
1st October 2025
Target population:
Adults aged 18 and over, excluding cancer care
Indications:
Licensed and off-label use in rheumatoid arthritis, Crohn’s disease, psoriasis, psoriatic arthritis, and other chronic inflammatory conditions
Administration routes:
Oral, subcutaneous
Monitoring requirements:
Blood tests, infection screening, vaccination advice, renal function assessment, pregnancy considerations
Responsible organizations:
HNY ICB, RDTC
Document type:
Shared Care Protocol
Contextual description:
Clinical guidance source detailing licensed and off-label methotrexate indications, administration, monitoring, and transfer protocols between specialist and primary care for adults in non-cancer services.
Year:
2023
Region / City:
Humber and North Yorkshire
Topic:
Learning and Development Policy
Document Type:
Policy
Organization:
Humber and North Yorkshire Integrated Care Board (ICB)
Author:
Senior Manager: Organisational Development & Learning and Development Lead
Target Audience:
ICB Employees
Approval Date:
07/09/2023
Amendment History:
7/9/23 - Updated policy from prior CCG organisations to ICB
Policy Number:
50
Version Number:
0.22
Equality Impact Assessment:
22/08/2023
Scope:
All Humber and North Yorkshire ICB employees
Mandatory Training:
Yes
Study Leave:
Yes
Year:
2025
Region / City:
Humber and North Yorkshire
Topic:
Establishment of Joint Committees
Document Type:
Report
Organization / Institution:
Humber and North Yorkshire Integrated Care Board
Author:
Natalie Caphane
Target Audience:
ICB Board members, Local Authority leaders
Period of Effect:
April 2025 - onwards
Approval Date:
March 12, 2025
Date of Changes:
N/A
Version:
HNY v1.0
Replaces version:
RDTC v1.0
Date published:
April 2025
Clinical content last reviewed:
October 2023
Next review date:
October 2025
Previous version publication date:
7th December 2023
Local approval date:
2nd April 2025
Approved by:
Humber and North Yorkshire ICB
Document type:
Shared Care Protocol
Therapeutic area:
Cardiology
Medicine:
Dronedarone
Target population:
Adults aged 18 years and over
Indication:
Maintenance of sinus rhythm after successful cardioversion in clinically stable adult patients with paroxysmal or persistent atrial fibrillation
Recommended dose:
400 mg twice daily with morning and evening meals
Initiation responsibility:
Specialist only
Prescribing restriction:
Not to be initiated in primary care for new patients
Monitoring requirements:
Liver function tests, urea and electrolytes including potassium and magnesium, serum creatinine, ECG
Regulatory references:
NICE TA 197; NICE NG 196
Intended audience:
NHS healthcare professionals
Geographical scope:
North West, North East and Yorkshire ICBs
Commercial use restriction:
Not permitted for commercial or marketing purposes
Year:
2025
Month:
November
Region:
Humber and North Yorkshire
Country:
United Kingdom
Document type:
Committee decision summary
Organisation:
Humber and North Yorkshire Area Prescribing Committee (HNY APC)
Approved by:
HNY APC
Date of approval:
3 December 2025
Reviewed by:
CPC
Scheduled review:
January meeting
Legal framework:
NICE technology appraisals implementation within NHS
Scope:
Medicines commissioning, formulary status, shared care protocols
Intended audience:
NHS healthcare professionals
Contact organisation:
HNY APC Professional Secretariat, Regional Drug and Therapeutics Centre, Newcastle upon Tyne
Usage restriction:
Not for commercial or marketing purposes
Year:
2023
Region / City:
N/A
Subject:
Genetic differentiation, metabolic analysis
Document Type:
Research Supplement
Institution:
N/A
Author:
N/A
Target Audience:
Researchers in genetics and agriculture
Period of Validity:
N/A
Approval Date:
N/A
Modification Date:
N/A
Year:
2025
Month:
November
Region:
Humber and North Yorkshire
Country:
United Kingdom
Document type:
Committee decision summary
Organisation:
Humber and North Yorkshire Area Prescribing Committee (HNY APC)
Approved by:
HNY APC
Date of approval:
3 December 2025
Reviewed by:
CPC
Scheduled review:
January meeting
Legal framework:
NICE technology appraisals implementation within NHS
Scope:
Medicines commissioning, formulary status, shared care protocols
Intended audience:
NHS healthcare professionals
Contact organisation:
HNY APC Professional Secretariat, Regional Drug and Therapeutics Centre, Newcastle upon Tyne
Usage restriction:
Not for commercial or marketing purposes
Document Type:
Supplementary statistical tables
Research Field:
Epidemiology; Public Health; Neurology
Topic:
Associations between smoking status, smoking dosage (pack-years), and risk of dementia
Health Outcomes Studied:
All-cause dementia; Alzheimer’s dementia; vascular dementia
Exposure Variables:
Smoking initiation, smoking cessation, sustained smoking, pack-year exposure
Population Size:
1,073,517 non-smokers and multiple smoking status groups
Statistical Measures:
Incidence rate per 1000 person-years; hazard ratio with 95% confidence interval
Observation Metric:
Person-years of follow-up
Analytical Approach:
Sensitivity analysis and subgroup interaction analysis
Adjusted Covariates:
Sex; age; low income; alcohol consumption; regular physical activity; body mass index; hearing loss; diabetes mellitus; hypertension; dyslipidemia
Subgroup Factors:
Low income; alcohol consumption; physical activity; obesity; hearing loss; diabetes mellitus; hypertension; dyslipidemia
Purpose:
Quantitative assessment of how smoking behavior and demographic or health factors relate to dementia incidence
Source Context:
Supplementary material accompanying an epidemiological research study
Document type:
Supplementary table
Study cohort:
Rotterdam cohort
Topic:
Clinicopathological characteristics and treatment response
Medical field:
Oncology
Variables described:
Age, tumor characteristics, response to first-line tamoxifen
Subgroups:
ISGHIGH, ISGLOW
Statistical analysis:
Statistical tests for subgroup differences indicated for each variable
Treatment referenced:
First-line tamoxifen
Population:
Patients included in the Rotterdam cohort
Section:
Supplementary material
Table number:
2
Year:
2026
Region:
Multicenter study
Topic:
Cystic fibrosis treatment outcomes
Document type:
Clinical study table
Institution:
University medical centers
Population:
Patients with cystic fibrosis
Treatment groups:
Never treated with CFTR modulators; Switched from lumacaftor/ivacaftor to ETI
Parameters measured:
Age, sex, sweat chloride, FEV1, FVC, BMI, pancreatic insufficiency, diabetes, chronic infections, CRP, ESR, leukocyte and neutrophil counts, platelets, IgG, albumin, hemoglobin, HbA1c, glucose
Statistical methods:
Chi-square, t-test, Mann-Whitney test
Data source:
ETI treatment initiation visit
Year:
Not specified
Region / City:
Not specified
Topic:
Respiratory infections, coinfections
Document type:
Research table
Author:
Not specified
Target audience:
Researchers, medical professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
The document provides a table detailing the types and frequencies of viral and bacterial respiratory coinfections in two subgroups:
invasive GAS and severe GAS infections.