№ lp_2_1_10373
File format: docx
Character count: 6647
File size: 53 KB
Standard operating procedure template outlining institutional requirements, hazard controls, storage, emergency response, waste management, and training documentation for laboratory use of particularly hazardous substances under MIOSHA Part 431.
Issuing Organization:
MIOSHA
Related Regulation:
MIOSHA Part 431 – Hazardous Work in Laboratories
Institution:
CMU (Central Michigan University)
Responsible Unit:
Environmental Health and Safety
Document Type:
Standard Operating Procedure (SOP) Template
Subject:
Use of Particularly Hazardous Substances in Laboratories
Applicable To:
Laboratory workers handling particularly hazardous substances
Scope:
Select carcinogens, reproductive toxins, and chemicals with high acute and chronic toxicity
Required Sections:
Chemical identification, hazards, PPE, engineering controls, storage, transportation, spill response, decontamination, waste disposal, SDS location, training verification
Compliance Reference:
CMU Chemical Hygiene Plan
Associated Resources:
NIOSH Pocket Guide to Chemical Hazards; CAMEO Chemicals Database of Hazardous Materials; MSDSonline Safety Data Sheet Database
Record Requirement:
Signed training acknowledgment by laboratory personnel and Trainer/Principal Investigator
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Chemical name:
Pyridine
CAS number:
110-86-1
Document type:
Standard operating procedures
Hazard classification:
Suspected human carcinogen (IARC Group 2B); animal carcinogen (ACGIH A3)
Physical state:
Clear to light yellow liquid
Odor:
Penetrating, nauseating, fishy odor
Signal word:
Danger
Flammability:
Highly flammable liquid and vapor
Exposure routes:
Skin absorption, inhalation, ingestion
Target organs:
Eyes, skin, respiratory system, blood, kidneys, liver, central nervous system
Exposure limits (DOSH):
TWA 5 ppm; STEL 10 ppm
Exposure limits (NIOSH):
TWA 5 ppm; 15 mg/m3
Exposure limits (ACGIH):
TLV 1 ppm; 3.1 mg/m3
Toxicological data (oral LD50):
891 mg/kg (rat); 1,500 mg/kg (mouse)
Toxicological data (dermal LD50):
1,121 mg/kg (rabbit)
Toxicological data (inhalation LC50):
17.1 mg/l, 4 hours (rat)
Required personal protective equipment:
Chemical safety goggles, butyl rubber or PVA gloves, lab coat
Engineering controls:
Certified laboratory chemical fume hood
Emergency equipment:
Eyewash station; emergency shower
Waste disposal requirements:
Collection as hazardous waste in sealed compatible containers with labeling
Storage conditions:
Secured, cool, dry, well-ventilated area; flammable storage
Incompatible materials:
Strong oxidizers, acids, bases
Designated area:
Laboratory fume hood and identified laboratory areas
Training and certification:
Hazard assessment and employee training records included
Year:
Not specified
Region / City:
Not specified
Topic:
Safety procedures for handling hazardous chemicals
Document type:
Standard Operating Procedures
Organization / Institution:
Not specified
Author:
Not specified
Target audience:
Laboratory staff and personnel handling Xylenes
Period of validity:
Not specified
Approval date:
Not specified
Date of revisions:
Not specified
Context:
Standard operating procedure document detailing the safety protocols for handling Xylenes, a hazardous chemical compound, in a laboratory environment.
Chemical name:
Toluene
CAS number:
108-88-3
Alternative names:
Toluol; Tolu-Sol; Methylbenzene; Methacide; Phenylmethane; Methylbenzol
Document type:
Standard operating procedures
Hazard classification:
Highly flammable liquid and vapor; reproductive toxin
Signal word:
Danger
Health hazards:
Aspiration hazard; skin and eye irritation; central nervous system effects; organ damage from prolonged or repeated exposure
Exposure limits:
DOSH TWA 100 ppm, STEL 150 ppm; OSHA TWA 200 ppm, ceiling 300 ppm, 500 ppm peak; NIOSH TWA 100 ppm, STEL 150 ppm
Toxicological data:
Oral LD50 (rat) 636 mg/kg; Dermal LD50 (rabbit) 14,100 mg/kg; Inhalation LC50 (rat) 49,000 mg/m³
Protective equipment:
Chemical safety goggles; nitrile, Viton, or PVA gloves; lab coat; chemical fume hood
Storage requirements:
Flammable materials storage; cool, dry, well-ventilated area; segregation from incompatible chemicals
Waste handling:
Collection as hazardous waste in sealed compatible containers with dangerous waste labeling
Applicable environment:
Laboratory setting
Responsible unit:
Environmental Health & Safety; Principal Investigator
Note:
Year
Topic:
Chemical Safety, Hazardous Chemicals, Laboratory Procedures
Document Type:
Standard Operating Procedure
Target Audience:
Laboratory Personnel, Safety Officers
Note:
Year
Topic:
Hazardous chemical safety
Document Type:
Standard Operating Procedure
Target Audience:
Laboratory staff, researchers
Note:
Year
Subject:
Hazardous chemicals handling
Document Type:
Standard Operating Procedures
Year:
Not specified
Region / City:
Not specified
Topic:
Hazardous Chemicals, Safety Procedures
Document Type:
Standard Operating Procedure
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Employees working with Potassium Permanganate
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Amendments:
Not specified
Year:
2023
Region / City:
Not specified
Subject:
Chemical Safety Procedures
Document Type:
Standard Operating Procedure
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Laboratory personnel, safety officers
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
STANDARD OPERATING PROCEDURES FOR HAZARDOUS AND PARTICULARLY HAZARDOUS CHEMICALS For Sodium Chloride
Year:
Not specified
Region / City:
Not specified
Topic:
Hazardous Chemicals Management
Document Type:
Standard Operating Procedures
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Laboratory personnel and safety officers
Effective Period:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified
Year:
2016
Region / City:
Geneva
Topic:
Human Rights, Family Rights, Sustainable Development, Poverty Eradication
Document Type:
Report
Institution:
United Nations Human Rights Council
Author:
United Nations High Commissioner for Human Rights
Target Audience:
Member States, United Nations Agencies, Civil Society Organizations
Period of Application:
2015–2030
Approval Date:
15 January 2016
Amendment Date:
None
Year:
2023
Location:
Atlanta, GA, USA
Document Type:
Working Instructions / Inventory Form
Regulatory Authority:
Drug Enforcement Administration (DEA)
Author:
Joe Smith
Intended Audience:
DEA Registrants and laboratory staff
Inventory Scope:
Schedule I – II and Schedule III – V Controlled Substances
Inventory Date:
05/01/23
Inventory Time:
Beginning of Business (BOB) / Close of Business (COB)
Employees Conducting Inventory:
Joe Smith, Joann Taylor
Note:
Department
Year:
1965
Region / City:
South Africa
Subject:
Medicines and related substances
Document Type:
Application form
Organization / Institution:
South African Health Products Regulatory Authority (SAHPRA)
Author:
South African Health Products Regulatory Authority
Target Audience:
Applicants wishing to import and distribute scheduled substances
Effective Period:
Five years from the date of issue
Approval Date:
Not specified
Amendment Date:
Not specified
Year:
2017
Region / City:
European Union
Topic:
Tattoo Ink Safety
Document Type:
Proposal
Organization / Institution:
European Chemicals Agency (ECHA)
Author:
European Chemicals Agency (ECHA)
Target Audience:
Public, regulatory bodies, tattoo industry
Period of Validity:
Not specified
Approval Date:
December 21, 2017
Amendment Date:
Not specified
Publication number:
2033
Publication date:
August 2022
Authorising body:
EPA Victoria
Publisher:
EPA Victoria
Jurisdiction:
Victoria, Australia
Document type:
Technical guidance
Legal framework:
Environment Protection Act 2017
Subject matter:
Naturally occurring chemical substances; contaminated land assessment; soil and groundwater
Intended users:
Land managers, contaminated land consultants, environmental auditors, environmental practitioners
Licence:
Creative Commons Attribution 4.0
Year:
2024
Region / city:
Global
Topic:
Emissions of HFC-23, Ozone layer depletion
Document type:
Scientific Assessment Report
Author:
S. A. Montzka, J. B. Burkholder, L. J. Carpenter, D. W. Fahey, K. W. Jucks, B. Safari, L. Western, K. M. Stanley, A. J. Manning, M. K. Vollmer, M. Sulbaek Andersen
Target audience:
Environmental scientists, policymakers, climate researchers
Period of validity:
2024-2025
Approval date:
15 September 2024
Date of revisions:
None
Note:
Year
Subject:
Controlled Substances Loss or Theft
Document Type:
Form
Organization / Institution:
UTSA
Year:
2002
Region / City:
Manchester
Topic:
Safety, Hazard Assessment, Chemical Risk
Document Type:
Risk Assessment Guidelines
Organization / Institution:
University of Manchester
Author:
Not specified
Target Audience:
Safety Officers, Laboratory Managers, Researchers
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
05/19
Region / city:
Kansas
Theme:
Environmental Remediation
Document type:
Application form
Organization / institution:
Kansas Department of Health and Environment
Author:
Kansas Department of Health and Environment
Target audience:
Facility owners, contractors, environmental remediation professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
Contextual description:
A form for requesting upgrades or modifications to underground storage tanks for petroleum products and hazardous substances in Kansas.
Year:
2023
Region / City:
United States
Theme:
e-Prescribing, Controlled Substances
Document Type:
User Guide
Organization / Institution:
Department of Veterans Affairs (VA), Office of Information and Technology (OIT)
Author:
Liberty IT Solutions
Target Audience:
Pharmacy package users, Automated Data Processing Application Coordinators (ADPAC), software users
Period of Validity:
Not specified
Approval Date:
Not specified
Amendment Date:
Not specified