№ files_lp_4_process_3_065234
File format: docx
Character count: 11527
File size: 35 KB
Year:
2019–2021
Region / Location:
United States
Topic:
Psychiatric Genetics, PTSD
Document Type:
Research Summary / Scientific Review
Institution:
Rosalind Franklin University of Medicine and Science
Author:
Monika A. Waszczuk
Target Audience:
Researchers and clinicians in psychiatry and genetics
Study Cohorts:
Psychiatric Genomics Consortium (PGC), Million Veterans Program (MVP)
Methods:
Genome-Wide Association Studies, Dimensional Phenotypic Analysis
Phenotypes Studied:
PTSD symptoms, trauma exposure, related psychiatric conditions
Sample Size:
30,000–250,000 participants across studies
Findings:
Identification of multiple genetic loci associated with PTSD and trauma-related traits
Endophenotypes:
Dimensional measures of symptom severity, lifetime trauma exposure
Relevance:
Genetic architecture of PTSD and transdiagnostic loci in psychiatric disorders
Data Collection Tools:
Clinician-Administered PTSD Scale (CAPS), PTSD Checklist (PCL)
Publication Date:
2021
Description:
Scientific article presenting GWAS findings on PTSD and trauma, emphasizing dimensional phenotypic approaches to reveal genetic loci associated with symptom severity and trauma exposure.
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Year:
Not specified
Region / City:
Not specified
Topic:
Unit Conversion, Dimensional Analysis
Document Type:
Worksheet
Author:
Not specified
Target Audience:
Students studying Chemistry
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Type of document:
Educational worksheet
Subject:
Chemistry
Topic:
Dimensional analysis and significant figures
Educational level:
Secondary education
Content elements:
Definitions, numerical exercises, unit conversions, rounding rules
Units of measurement:
Metric and customary units
Referenced constants:
1 mole Na = 23.0 g
Answer format requirements:
Correct units, significant figures, boxed answers
Year:
Not specified
Region / City:
Not specified
Topic:
Dimensional analysis, unit conversions
Document Type:
Practice Problems
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Students
Period of Action:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
Not specified
Region / City:
Not specified
Subject:
Urban planning and zoning regulations
Document Type:
Legal/Regulatory text
Authority / Institution:
Planning Board
Target Audience:
Developers, architects, urban planners
Relevant Period:
Current zoning regulations
Section:
§ 410-5.1
Topics Covered:
Multi-family building allowances, site plan review, special permit, wall effect mitigation
Document Type:
Data Management and Sharing Plan
Policy Framework:
NIH Policy for Data Management and Sharing; Genomic Data Sharing Policy
Funding Agency:
National Institutes of Health (NIH)
Related Repositories:
NIMH Data Archive (NDA); dbGaP
Study Registration:
dbGaP
Subject Population:
500 human research subjects
Data Types:
Whole genome sequencing data; phenotypic data; clinical data
Genomic Data Formats:
FASTQ; SAM/BAM; BED; VCF
Data Standards:
NOT-MH-20-067 common data elements; Genomics Subject (genomics_subject02); Genomics Sample (genomics_sample03); Structured Clinical Interview for DSM-V (scidv_dep01); MATRICS Consensus Cognitive Battery (matrics01)
Assessment Instruments:
DSM Crosscutting; WHODAS 2.0; PHQ-9; GAD-7
Software and Tools:
Illumina sequencing pipelines; Genome Analysis Toolkit (GATK)
Data Submission Timeline:
Initial deposit 12 months after award start; subsequent deposits every six months
Data Access Conditions:
Broad data sharing consent; controlled access via NDA
Data Availability Period:
At end of grant award or upon publication submission; long-term preservation managed by NDA
Year:
2023
Region / city:
Not specified
Topic:
Chronic kidney disease, Genetic and phenotypic analysis
Document type:
Research paper
Institution / organization:
Not specified
Author:
Not specified
Target audience:
Researchers, healthcare professionals, geneticists
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Document type:
Supplementary material
Subject:
Microbiology and bacterial taxonomy
Focus organism:
Pseudescherichia liriopis sp. nov. L3T
Associated plant host:
Liriope platyphylla
Test plant species:
Daucus carota subsp. sativus
Authors:
Inhyup Kim; Haejin Woo; Geeta Chhetri; Sunho Park; Taegun Seo
Affiliation:
Department of Life Science, Dongguk University-Seoul, Goyang 10326, Republic of Korea
Corresponding author:
Taegun Seo
Contact email:
[email protected]
Methods included:
FastANI analysis; antiSMASH analysis; API 20NE tests; dDDH and ANI genomic comparisons
Data included:
EPS production assay; PEG and NaCl resistance; growth range; hydrolysis tests; genome statistics; phylogenetic comparisons
Genome accession number (L3T):
JANKYC000000000
Genome size (L3T):
4,304,575 bp
DNA G+C content:
56.5 mol%
Number of compared species:
29
Year:
2024-25
Region / City:
Varanasi, Uttar Pradesh, India
Subject:
Genotype × Environment Interactions, Phenotypic Plasticity
Document Type:
Research Article
Organization / Institution:
ICAR-IIVR
Author:
Choudhary et al.
Target Audience:
Researchers, Plant Breeders
Period of Validity:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified
Keywords:
Brinjal, climate-resilient breeding, genotype × environment interaction, hybrids, inbreds, phenotypic plasticity, seasonal stability
Context:
The document is an academic research article examining genotype by environment interactions in brinjal, focusing on the phenotypic stability and plasticity of qualitative traits across two different seasonal environments.
Year:
Not specified
Country:
United States
Field:
Genomics; Biomedical Research; Data Management
Document Type:
Research Data Management and Sharing Plan
Organization:
National Institutes of Health (NIH)
Related Repositories:
NIMH Data Archive (NDA); dbGaP
Research Data Types:
Genomic sequencing data; Phenotypic data; Clinical data
Number of Research Subjects:
500
Data Standards:
DSM Crosscutting; WHODAS 2.0; PHQ-9; GAD-7; MATRICS Consensus Cognitive Battery
File Formats:
FASTQ; SAM/BAM; BED; VCF
Software / Tools:
Illumina pipelines; Genome Analysis Toolkit (GATK)
Data Submission Timeline:
Starting 12 months after award and every six months thereafter
Data Access Conditions:
Broad data sharing with participant consent; controlled access through NDA
Persistent Identifier:
Digital Object Identifier (DOI) assigned to NDA studies
Associated Policies:
NIH Policy for Data Management and Sharing; Genomic Data Sharing Policy
Year:
2013
Region / City:
United States
Topic:
PTSD Screening
Document Type:
Measurement instrument
Organization:
Department of Veterans Affairs
Author:
F. W. Weathers, B. T. Litz, T. M. Keane, P. A. Palmieri, B. P. Marx, P. P. Schnurr
Target Audience:
Clinicians, researchers
Period of validity:
Ongoing
Approval Date:
2013
Modification Date:
Not specified
Year:
[Year]
Region / City:
[City]
Theme:
Medical Opinion
Document Type:
Independent Medical Opinion
Organization / Institution:
[Medical Facility Name]
Author:
Dr. Grant Thomas
Target Audience:
Healthcare providers, VA personnel
Period of validity:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Year:
2024
Region / City:
Wales
Topic:
PTSD treatment guidelines
Document type:
Algorithm
Organization / Institution:
Traumatic Stress Wales
Author:
Dr. Mathew D Hoskins, Professor Jonathan I Bisson
Target Audience:
Healthcare professionals
Period of validity:
Ongoing
Approval date:
June 2024
Date of changes:
June 2024
Change Date:
February 3, 2016
Jurisdiction:
United States
Subject Area:
Veterans benefits law
Topic:
Service connection for posttraumatic stress disorder
Document Type:
Administrative guidance manual section
Issuing Body:
Department of Veterans Affairs
Legal References:
38 CFR 3.304(f); 38 CFR 4.125; 38 U.S.C. 1154(b); M21-1 Adjudication Procedures Manual
Covered Populations:
Veterans
Scope:
Development and adjudication of PTSD service connection claims
Source Type:
Government administrative guidance
Year:
2015
Region / city:
United States
Topic:
Posttraumatic Stress Disorder (PTSD), Service Connection
Document type:
Legal / Regulatory Guide
Organization:
Department of Veterans Affairs (VA)
Author:
Not specified
Target audience:
Veterans and VA administrators
Effective period:
From April 15, 2015
Approval date:
April 15, 2015
Date of changes:
Not specified
Year:
2022
Region / city:
United States
Topic:
Posttraumatic Stress Disorder (PTSD), Military Sexual Trauma (MST), Veterans Affairs
Document Type:
Internal procedure guidelines
Organization:
Department of Veterans Affairs (VA)
Author:
VA MRRC
Target Audience:
VA personnel, Veteran Service Representatives (VSRs), MRRC staff
Period of Effect:
Ongoing
Approval Date:
August 10, 2022
Modification Date:
Not specified
Year:
2024
Region / City:
USA
Topic:
Trauma, PTSD, Addiction
Document Type:
Research/Clinical Overview
Organization:
Treatment Innovations
Author:
Lisa Najavits, PhD
Target Audience:
Clinicians, Therapists, Researchers
Period of Activity:
Ongoing
Approval Date:
N/A
Modification Date:
N/A
Year:
2008, 2010, 1977, 2013, 1995, 2013, 2008, 2005, 2006, 2013, 1979, 1985, 2013, 2008, 1988, 1996, 2005, 2010, 2014, 2008, 2012, 2010
Country:
Israel, USA, Taiwan
Mind/Body practices:
Hypnotherapy, Transcendental Meditation, MBSR, Progressive Muscle Relaxation, Mantram Meditation, Relaxation Techniques, Tai Chi, Acupuncture, Partner Massage Therapy, Imagery Rehearsal
Population:
Veterans, Military
Study Design:
RCT, Observational
Outcomes:
PTSD symptoms, depression, anxiety, stress reactions, sleep quality, anger, smoking abstinence, quality of life, craving for substance
Measures:
CAPS, IES, BDI, BSI, PCL, Visual Subjective Sleep Quality Questionnaire, PTSD scales, Perceived Stress Scale, Minnesota Nicotine Withdrawal Scale, various questionnaires
Measurement points:
Baseline, Post-treatment, Follow-up (1 month, 3 months, 6 months, 12 months)
Number of subjects:
8-286
Comparison group:
Control groups, no intervention, or other treatments
Year:
2024
Region / City:
USA
Topic:
PTSD, Substance Abuse, Treatment
Document Type:
Clinical Guidelines
Organization:
Treatment Innovations
Author:
Lisa Najavits, PhD
Target Audience:
Healthcare professionals, therapists, clinicians
Period of Application:
Ongoing
Approval Date:
1/1/24
Modification Date:
N/A
Treatment Approach:
Cognitive-behavioral therapy, Coping skills training, Exposure therapy
Key Symptoms:
Intrusion, Avoidance, Negative thoughts, Arousal
Co-occurring Disorders:
PTSD, Substance-related disorders
Gender Disparities:
Higher PTSD rates in women, higher substance abuse in men
Substance Use:
Cocaine, opioids
Treatment Focus:
Dual treatment for PTSD and substance abuse
Cultural Sensitivity:
Tailoring treatment to cultural context
Recovery Model:
Abstinence or harm reduction
Evidence Base:
Over 45 published research articles
Contextual Description:
Clinical guideline for treating PTSD and substance abuse using the Seeking Safety model, emphasizing integrated treatment for both disorders.
Year:
2016
Region / City:
Greater Manchester, UK
Subject:
Mental Health, Trauma, PTSD, Emergency Services
Document Type:
Journal Article
Institution:
University of Salford, Bucks New University
Authors:
Elaine Beaumont MSc, Mark Durkin MSc, Sue McAndrew PhD, Colin Martin PhD
Target Audience:
Fire Service Personnel, Mental Health Professionals
Period of Study:
Not specified (pre- and post-therapy measures)
Date Published Online:
29 November 2016
Volume / Issue:
Volume 9, e34
DOI:
https://doi.org/10.1017/S1754470X16000209
Contextual Description:
Peer-reviewed journal article presenting a study on the effects of combining compassion focused therapy with trauma-focused cognitive behavioural therapy for firefighters experiencing PTSD, anxiety, depression, and low self-compassion.
Year:
N/A
Region / City:
N/A
Subject:
PTSD, Mental Health Training
Document Type:
Training Material
Institution:
National IAPT
Author:
N/A
Target Audience:
Healthcare Professionals, Mental Health Practitioners
Period of Validity:
N/A
Approval Date:
N/A
Date of Changes:
N/A