№ files_lp_4_process_2_59601
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Observational cohort study reporting prevalence of positive CT findings and incidental lung cancers among HIV-infected adults undergoing low-dose CT screening, with risk factors and procedural outcomes detailed.
Year: 2023
Region / City: Copenhagen, Denmark
Topic: HIV, lung cancer, computed tomography
Document Type: Research article, concise communication
Institution: Rigshospitalet, University of Copenhagen; University of Manchester
Authors: Andreas Ronit, Thomas Kristensen, Ditte M. Klitbo, Marco Gelpi, Anna Kalhauge, Thomas Benfield, Jan Gerstoft, Jens Lundgren, Jørgen Vestbo, Klaus F. Kofoed, Susanne D. Nielsen
Target Audience: Medical researchers, clinicians in infectious diseases and radiology
Study Design: Observational, longitudinal cohort study
Sample Size: 901 participants, 113 high-risk individuals
Screening Method: Low-dose computed tomography (LDCT)
Primary Outcomes: Positive CT images, histologically confirmed lung cancer
Risk Factors Assessed: CD4+ count <500 cells/µL, CD4+ nadir <200 cells/µL
Adverse Events: None serious during invasive procedures
Trial Registration: NCT02382822
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Topics: Co-morbidity COCOMO HIV-infected