№ files_lp_4_process_2_47040
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Figure legends providing detailed experimental results on PARP inhibitor resistance in PEO1 cells, including analyses of gene expression, RNA modifications, Wnt signaling regulation, and drug response in cell lines and mouse xenograft models.
Year: 2026
Research Institution: [Not specified in document]
Cell Lines: PEO1, TOV21G, UWB1.289
Genes Studied: BRCA1, BRCA2, FZD10, ALKBH5, FTO, METTLE3, METTLE14, YTHDF2, HuR, IGF2BP2
Drugs: Olaparib, Niraparib, Rucaparib, XAV939
Experimental Methods: Immunoblotting, qRT-PCR, RNA electrophoresis, shRNA knockdown, lentiviral infection, HR and NHEJ reporter assays, apoptosis assays, mouse xenograft models
Target Pathways: Wnt signaling, DNA repair pathways (HR and NHEJ)
Data Analysis Tools: NIH ImageJ, statistical analysis via two-tailed t-test
Supplement Type: Figure legends for supplementary data in molecular biology research
End Date of Experimentation: Not specified
Price: 8 / 10 USD
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