№ lp_2_1_32691
Analysis of predicted versus actual patient utilisation and prescription data for tolvaptan in adults with ADPKD based on PBS records.
Year: 2021
Region: Australia
Topic: Pharmacology / Drug utilisation
Document type: Report
Organization: Drug Utilisation Sub-Committee (DUSC), Department of Health, Services Australia
Drug: Tolvaptan
Condition: Autosomal dominant polycystic kidney disease (ADPKD)
Population: Adults with chronic kidney disease stage 1–3
Data source: Pharmaceutical Benefits Scheme (PBS) database
Date of PBS listing: 1 January 2019
Treatment criteria: Nephrologist management, eGFR 30–89 mL/min/1.73m², evidence of rapidly progressing disease
Monitoring requirements: Liver function tests prior to initiation, monthly for 18 months, then every 3 months
Dosage forms: 15 mg, 30 mg, 45 mg, 60 mg, 90 mg tablets in split-dose regimens
Analysis period: First and second year of PBS listing
Price: 8 / 10 USD
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