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This research paper investigates the relationship between hypertension and dietary salt intake, examining its effect on inflammation through cytokine levels in individuals from Zambia and other global institutions.
Year:
2023
Region / city:
Livingstone, Zambia; Lusaka, Zambia; Twickenham, London, UK; Nashville, TN, USA
Subject:
Hypertension, dietary salt, inflammation
Document type:
Research study
Organization / institution:
Mulungushi University, University of Zambia, St. Mary’s University, Vanderbilt University Medical Center
Author:
Sepiso K. Masenga, Leta Pilic, Benson M. Hamooya, Selestine Nzala, Geoffrey Kwenda, Douglas C. Heimburger, Wilbroad Mutale, John R. Koethe, Annet Kirabo, Sody M. Munsaka
Target audience:
Researchers, healthcare professionals
Period of validity:
Not specified
Approval date:
Not specified
Modification date:
Not specified
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Authors:
Chi Wang; Mengyi Zheng; Cuijuan Yun; Zekun Feng; Yanjie Li; Shuohua Chen; Shouling Wu; Hao Xue
Academic Degrees:
MD
Document Type:
Supplementary Data
Study Design:
Longitudinal cohort study
Main Topic:
Systemic inflammation, atherogenic dyslipidemia, and incident cardiometabolic disease
Biomarkers Assessed:
C-reactive protein (CRP); Atherogenic index of plasma (AIP)
Outcomes:
Cardiometabolic disease (CMD); Cardiovascular disease; Type 2 diabetes mellitus (T2DM)
Statistical Measures:
Hazard ratios (HR); 95% confidence intervals (CI)
Subgroup Analyses:
Sex-specific analyses (women n=16,870; men n=61,336)
Analytical Methods:
Sensitivity analyses; Time-dependent variable models; Cross-lagged analysis (2006–2010); Mediation analysis
Adjustment Variables:
Age; Sex; Body mass index; Blood pressure; Heart rate; Fasting blood glucose; LDL cholesterol; Estimated glomerular filtration rate; Smoking status; Alcohol consumption; Physical activity; Educational level; Salt intake; Sleep disorders; Family history of myocardial infarction, stroke, and diabetes; Antihypertensive and lipid-lowering medication use
Year:
2023
Region / city:
Milano
Topic:
Chronic inflammation, microglia, neuroinflammation
Document type:
Research paper
Institution:
Università degli Studi di Milano
Authors:
Giacomo Costa Broccardi, Simone Giovanni Scaglioni, Sabrina D’Amelio, Donatella Lattuada, Raffaella Molteni, Maria Grazia Cattaneo
Target audience:
Researchers, biomedical scientists, students in related fields
Period of validity:
Not specified
Approval date:
Not specified
Date of modifications:
Not specified
Context:
The paper explores the effects of chronic low-grade inflammation on microglial cells in vitro, focusing on cytokine expression and cellular responses under inflammation.
Date:
January 17, 2021
Type of document:
Cover letter
Purpose:
Submission of an original research article for publication
Journal:
Functional Foods in Health and Disease
Author:
Johnny Percy Ambulay Briceño, MSc
Affiliation:
Micronutrients Laboratory, Laboratories for Research and Development, Universidad Peruana Cayetano Heredia
Institution address:
Av. Honorio Delgado 430, San Martin de Porres, Lima 31, Perú
Subject of manuscript:
Effects of oil emulsion from Plukenetia huayllabambana on nitric oxide, leptin, antioxidant and inflammation markers in obese rats
Funding statement:
Article publication fee of $895.00 US dollars to be paid via PayPal invoice
Publication status:
Not published and not under consideration elsewhere
Recommended peer reviewers:
Salma M. Eraky; Solomon E. Owumi; Zatollah Asemi; Ghadha Ibrahim Fouad; Jing Hui
Co-authors:
Percy A. Rojas; Olga S. Timoteo; Teresa V. Barreto; Zayra N. Vila; M. B. De los Santos; Maria Eguiluz; Ana Colarossi
Document type:
Supplementary material
Components:
Supplementary Figures; Supplementary Table; Supplementary references
Figures included:
Figure S1; Figure S2; Figure S3; Figure S4
Table included:
Table S1
Research topic:
Gut microbiota, intestinal inflammation and ulcerative colitis in murine models
Experimental subjects:
Mice
Biological focus:
Colonic tissue; intestinal barrier function; immune response; gut microbiota at genus level
Analytical methods mentioned:
Western blot; immunoblot; densitometric analysis
Key elements:
SCR-CDs synthesis; organ weight measurement; bacterial genera classification as beneficial or harmful; associated pathological states
Referenced conditions:
Ulcerative colitis; inflammatory bowel disease; colitis
Cited works:
Peer-reviewed journal articles with DOIs listed
Year:
2026
Region / city:
Istanbul, Turkey
Topic:
Histology, Endocrinology, Ovarian Transplantation
Document type:
Research Article
Author:
Ph.D. Ali DOĞAN, Assoc. Prof. Dr. Ayşe YAZAR
Target audience:
Scientists, Medical Researchers, Healthcare Professionals
Period of validity:
N/A
Approval date:
N/A
Date of last revision:
N/A
Year:
2026
Region / City:
Beijing, China
Subject:
Biochemistry, Cellular Stress, Inflammation
Document Type:
Supplementary Information
Institution:
Peking University, College of Urban and Environmental Sciences
Authors:
Wenxin Hu, Qiyue Kang, Chenhao Zhang, Haojia Ma, Chenke Xu, Yi Wan, Jianying Hu
Correspondence:
Dr. Jianying Hu, [email protected]
Experimental Models:
In vitro cellular assays, qRT-PCR analysis
Chemicals:
Triphenyl phosphate (TPHP), DMEM-F12, Fetal bovine serum, Trizol
Analytical Methods:
Mass spectrometry, PCR primers listed, fluorescence assays
Purpose:
Investigation of phospholipid saturation effects on endoplasmic reticulum stress and inflammatory response
Year:
2026
Region / City:
Global
Topic:
Genetic research, Chronic inflammation, Genome-wide association studies
Document Type:
Research Supplement
Organization / Institution:
Multiple academic institutions
Author:
Multiple contributors
Target Audience:
Researchers, Scientists, Medical professionals
Period of validity:
Ongoing
Date of Approval:
N/A
Date of Changes:
N/A
Year:
2026
Region / City:
Baghdad, Iraq
Topic:
Type 2 Diabetes Mellitus, Periodontal Disease, Fungal Infections, Obesity, Inflammation
Document Type:
Research Article
Institution:
Gilgamesh University, College of Health and Medical Techniques
Authors:
Mohammed Mohaibes, Ammar Sabar, Mayada Al-khafaji
Target Audience:
Medical researchers, clinicians, and healthcare professionals
Study Design:
Case-control study
Sample Size:
150 participants (75 T2DM patients, 75 healthy controls)
Methods:
Oral swabs, blood analysis for CRP and ESR, fungal isolation via microscopy, culture, VITEK® 2 system
Period:
Not explicitly stated
Publication Status:
Preprint / Manuscript
Keywords:
Type 2 Diabetes Mellitus, Periodontal disease, Fungal infection, Obesity, Inflammation, CRP, ESR
Correspondence:
[email protected]
Year:
2018
Region / city:
Vale of York, Scarborough and Ryedale
Theme:
Varicose Veins Management
Document type:
Commissioning Policy
Organization:
NHS Vale of York and Scarborough and Ryedale CCGs
Author:
Not specified
Target audience:
Healthcare professionals, Primary care clinicians, Vascular surgeons
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
2018
Document type:
Guidance document
Subject:
Informed consent in interventional clinical trials
Population:
Healthy adult participants
Scope:
Interventional clinical trials with trial medicine
Jurisdiction:
Belgium
Organizations mentioned:
CT College; Healixia; Ethics Committees; Belgian Data Protection Authority
Language versions:
English; French; Dutch
Intended users:
Clinical trial sponsors
Regulatory context:
Ethics Committee submission requirements
Version:
1.0
Year:
2024
Region / City:
Ireland
Topic:
Clinical Trials, Legal Agreements, Healthcare
Document Type:
Explanatory Note
Organization:
HSE, IPHA
Target Audience:
Contract Research Organizations, Hospitals, Pharmaceutical Companies
Effective Date:
20.05.24
Related Date:
20.05.24
Approval Date:
20.05.24
Year:
2021
Region / City:
Brussels
Topic:
Clinical Research Ethics
Document Type:
Submission Form
Institution:
Saint-Luc University Clinics (CUSL)
Author:
Ethics Committee
Target Audience:
Researchers, Clinical Trial Investigators
Period of Validity:
2021-2022
Approval Date:
N/A
Date of Changes:
N/A
Year:
2019
Region / City:
Toronto, Canada
Topic:
Informed consent, Clinical trial
Document Type:
Template, Informed consent form
Institution:
SickKids
Author:
SickKids REB
Target Audience:
Parents, Researchers
Effective Period:
N/A
Approval Date:
November 14, 2019
Modification Date:
N/A
Year:
2019
Region / City:
SickKids, Canada
Topic:
Clinical Trial Consent Form
Document Type:
Template
Organization:
SickKids Research Ethics Board
Author:
SickKids
Target Audience:
Research Teams, Clinical Trial Participants
Effective Period:
N/A
Approval Date:
N/A
Amendment Date:
N/A
Year:
Spring 2009
Region / City:
Dartmouth-Hitchcock Medical Center
Subject:
Interventional Radiology Procedures
Document Type:
Clinical Manual
Institution:
Dartmouth-Hitchcock Medical Center
Author:
Not specified
Target Audience:
Medical professionals in interventional radiology
Effective Period:
Ongoing for clinical rotations
Approval Date:
Spring 2009
Date of Last Revision:
Not specified
Year:
2024
Region / City:
United Kingdom
Topic:
Health Technology Evaluation
Document Type:
Meeting Minutes
Organ / Institution:
National Institute for Health and Care Excellence (NICE)
Author:
Committee members and NICE staff
Target Audience:
Healthcare professionals, policy makers, and stakeholders in health technology evaluation
Period of validity:
10 October 2024
Approval Date:
10 October 2024
Date of Changes:
None
Note:
Year
Topic:
Clinical Research / Protocol Development
Document Type:
Protocol Template
Organization / Institution:
DMID
Author:
DMID
Target Audience:
Clinical Researchers, Investigators
Document type:
Sponsor statement template
Subject:
Use of Belgian Model Informed Consent Form for vaccine trials in adult healthy volunteers
Related procedure:
Clinical trial application
Scope:
Interventional trials with investigational vaccines
Geographical reference:
Belgium
Applicable to:
Sponsors of clinical trials
Referenced document:
Belgian Model ICF for Vaccine Trials in Adult Healthy Volunteers
Required information:
EU number, trial number, sponsor details, adaptations to mandatory text if applicable
Signature requirement:
Sponsor representative in the Member State
Date format:
DD/MMM/YYYY