№ files_lp_4_process_2_89072
File format: docx
Character count: 1553
File size: 210 KB
An educational document summarizing the genetic causes, symptoms, and management approaches for cystic fibrosis, including both medical and lifestyle interventions.
Year:
2016
Author:
Tamia Jackson
Date:
March 11, 2016
Period/Class:
5th period
Topic:
Cystic Fibrosis
Document Type:
Educational overview
Intended Audience:
Students
Key Subjects:
Genetic causes, airway clearance, inhaled medications, nutrition, fitness, CFTR modulators, lung transplantation
Related Conditions:
Fibrocystic Disease of the pancreas, Mucoviscidosis
Medical Note:
There is no cure for Cystic Fibrosis
Price: 8 / 10 USD
The file will be delivered to the email address provided at checkout within 12 hours.
The file will be delivered to the email address provided at checkout within 12 hours.
Don’t have cryptocurrency yet?
You can still complete your purchase in a few minutes:- Buy Crypto in a trusted app (Coinbase, Kraken, Cash App or any similar service).
- In the app, tap Send.
- Select network, paste our wallet address.
- Send the exact amount shown above.
The final amount may vary slightly depending on the payment method.
The file will be sent to the email address provided at checkout within 24 hours.
The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2014
Region / city:
Qatar
Topic:
Medical Research
Document Type:
Research Article
Author(s):
Atqah AbdulWahab, Saad J Taj-Aldeen, Emad Ibrahim, Shaikha H Abdulla, Ramees Muhammed, Irshad Ahmed, Yasmine Abdeen, Omnia Sadek, Marawan Abu-Madi
Target Audience:
Medical professionals, researchers in infectious diseases
Date of approval:
2014
Note:
Contextual description
Year:
2020
Region / City:
Zhejiang Province, China
Field:
Gynecology
Document Type:
Case Report
Organization / Institution:
Zhejiang University School of Medicine, Women’s Hospital
Authors:
Zhou Y, Zheng-Yun Chen, Xin-Mei Zhang
Target Audience:
Medical professionals, researchers in gynecology
Period of validity:
N/A
Date of approval:
N/A
Date of changes:
N/A
Date received:
September 2, 2019
Date revised:
November 28, 2019
Date accepted:
December 13, 2019
Date published online:
January 6, 2020
Keywords:
Cystic adenomyosis, Dysmenorrhea, Levonorgestrel containing intrauterine device, Myomectomy, Case report
URL:
https://www.wjgnet.com/2307-8960/full/v8/i1/188.htm
DOI:
https://dx.doi.org/10.12998/wjcc.v8.i1.188
Context:
This is a medical case report detailing a rare instance of giant exophytic cystic adenomyosis with a levonorgestrel-containing intrauterine device out of the uterine cavity following uterine myomectomy.
Authors:
Noelia Rodriguez Mier; Senne Cuyx; Kris De Boeck; Marijke Proesmans; Mieke Boon; Lieven Dupont; Kaline Arnauts; Elke De Wachter; Stephanie Van Biervliet; Monique Lequesne; Vicky Nowé; Hedwige Boboli; Anabela Santo Ramalho; François Vermeulen; on behalf of the Belgian Organoid Project
Affiliations:
KU Leuven; University Hospital Leuven; University Hospital Brussels; Ghent University Hospital; Antwerp University Hospital; GZA Hospital; CHR Citadelle
Country:
Belgium
Research field:
Cystic fibrosis; CFTR modulators; organoid research; personalized medicine
Study population:
60 people with cystic fibrosis homozygous for F508del
Genetic focus:
F508del CFTR mutation (homozygous)
Interventions studied:
Elexacaftor/tezacaftor/ivacaftor; Tezacaftor/ivacaftor
Methods:
Patient-derived intestinal organoids from rectal biopsies; forskolin-induced swelling assay; comparison with clinical outcomes
Clinical outcomes assessed:
Lung function; sweat chloride levels; body weight; pulmonary exacerbations
Type of document:
Scientific research article
Source:
PubMed
DOI / Identifier:
40883119
Year:
2023
Region / City:
Royal Devon & Exeter Hospital, Wonford, UK
Topic:
Healthcare, Physiotherapy
Document Type:
Job Description
Organization / Institution:
Royal Devon University Healthcare NHS Foundation Trust
Author:
N/A
Target Audience:
Healthcare professionals, physiotherapists
Period of Validity:
N/A
Approval Date:
N/A
Amendment Date:
N/A
Year:
2025
Organization:
Alder Hey Children’s NHS Foundation Trust
Department:
Department of Respiratory Medicine
Document type:
Patient information leaflet
Target audience:
Patients, parents and carers of children with cystic fibrosis
Topic:
Genetics of cystic fibrosis, carrier testing, reproductive options
Review date:
March 2025
Contact:
Tel: 0151 228 4811, www.alderhey.nhs.uk
Location:
Liverpool, United Kingdom
Year:
Not specified
Region / Area:
Europe
Subject:
Post-authorisation safety and efficacy studies in cystic fibrosis registries
Document Type:
Application form
Organization:
European Cystic Fibrosis Society Patient Registry (ECFSPR)
Related Organization:
European Medicines Agency (EMA)
Applicant Type:
Marketing Authorisation Holder
Purpose:
Submission of requests for registry data for PASS / PAES studies
Required Attachments:
Study protocol; Statistical analysis plan
Submission Method:
Email submission to [email protected]
Key Sections:
Applicant details; Study information; Cohort definition; Statistical methods; Data requirements
Population Scope:
Patients included in the European Cystic Fibrosis Society Patient Registry
Historical Data Availability:
2008–2023
Fee Structure:
€5,000 handling; €25,000 review and feasibility assessment; €5,000 application modification
Governance Note:
Individual country applications outside ECFSPR governance may apply separate fees
Year:
2023
Region / City:
United Kingdom
Theme:
Health-related quality of life, Cystic fibrosis
Document Type:
Research Article
Author:
Rana Altabee, Siobhan B. Carr, Jaince Abbott, Rory Cameron, Daniel Office, Nicholas J. Simmonds, Jennifer A. Whitty, David Turner, Garry Barton
Target Audience:
Researchers, healthcare professionals, policy makers
Period of Study:
July 2020 – March 2021
Approval Date:
2023
Date of Changes:
None
Year:
2026
Location:
University of Cincinnati Hospital, 8 East Unit
Subject:
Cystic Fibrosis inpatient care and hospital protocols
Document Type:
Patient guidance / hospital procedure
Institution:
UC Hospital Pulmonary Consult Service
Author:
CF Nurse Practitioner Angela Oder
Target Audience:
CF patients and their families
Admission Requirements:
Direct or scheduled CF admissions
Infection Control:
Droplet & Contact isolation, personal protective equipment required
Dietary Guidelines:
High calorie diet (3000 cal/day), extended menu for CF patients
Medical Monitoring:
Vital signs every 8 hours, weight 2–4 times per week, glucose monitoring as needed
Therapy and Exercise:
4 respiratory therapy sessions/day, encouraged physical activity, home IV setup guidance upon discharge
Follow-up:
Appointment within 2 weeks post-discharge
Year:
2014
Region / city:
Qatar
Topic:
Medical Research
Document Type:
Research Article
Author(s):
Atqah AbdulWahab, Saad J Taj-Aldeen, Emad Ibrahim, Shaikha H Abdulla, Ramees Muhammed, Irshad Ahmed, Yasmine Abdeen, Omnia Sadek, Marawan Abu-Madi
Target Audience:
Medical professionals, researchers in infectious diseases
Date of approval:
2014
Note:
Contextual description
Year:
2023
Region / City:
Wuhan, China
Topic:
Gene expression, liver fibrosis, HCC
Document Type:
Research Article
Organization / Institution:
Zhongnan Hospital of Wuhan University, Wuhan University
Author:
Not specified
Target Audience:
Researchers, clinicians, medical professionals
Duration:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Note:
Context
Year:
2010-2024
Region / city:
Asia-Pacific
Subject:
Hepatology
Document Type:
Clinical Practice Guidelines
Organization / Institution:
Asian Pacific Association for the Study of the Liver (APASL)
Author:
APASL
Target Audience:
Healthcare professionals
Period of validity:
2010-2024
Date of approval:
2010
Date of revisions:
2024
Context:
Collection of clinical practice guidelines and consensus statements issued by the Asian Pacific Association for the Study of the Liver on various hepatological conditions, including hepatocellular carcinoma, hepatitis B and C, liver transplantation, and metabolic diseases.
Authors:
Noelia Rodriguez Mier; Senne Cuyx; Kris De Boeck; Marijke Proesmans; Mieke Boon; Lieven Dupont; Kaline Arnauts; Elke De Wachter; Stephanie Van Biervliet; Monique Lequesne; Vicky Nowé; Hedwige Boboli; Anabela Santo Ramalho; François Vermeulen; on behalf of the Belgian Organoid Project
Affiliations:
KU Leuven; University Hospital Leuven; University Hospital Brussels; Ghent University Hospital; Antwerp University Hospital; GZA Hospital; CHR Citadelle
Country:
Belgium
Research field:
Cystic fibrosis; CFTR modulators; organoid research; personalized medicine
Study population:
60 people with cystic fibrosis homozygous for F508del
Genetic focus:
F508del CFTR mutation (homozygous)
Interventions studied:
Elexacaftor/tezacaftor/ivacaftor; Tezacaftor/ivacaftor
Methods:
Patient-derived intestinal organoids from rectal biopsies; forskolin-induced swelling assay; comparison with clinical outcomes
Clinical outcomes assessed:
Lung function; sweat chloride levels; body weight; pulmonary exacerbations
Type of document:
Scientific research article
Source:
PubMed
DOI / Identifier:
40883119
Medicine:
Pirfenidone 267 mg capsule
Brand name:
Esbriet®
Manufacturer:
Roche Products Pty Ltd
Quantity:
270 capsules
Maximum quantity:
1
Number of repeats:
5
Program:
Section 100 – Highly Specialised Drugs Program
Schedule:
General Schedule (Code GE)
Condition:
Idiopathic pulmonary fibrosis
Treatment phases:
Initial treatment; Continuing treatment; Initial PBS-subsidised treatment (grandfather patient)
Restriction level:
Restricted benefit – Authority Required
Authority method:
In Writing; Telephone; Emergency; Electronic; Streamlined
Prescriber requirement:
Respiratory physician or specialist physician experienced in idiopathic pulmonary fibrosis
Population criteria:
Patients aged 40 years or older
Clinical criteria (initial):
Confirmed diagnosis of idiopathic pulmonary fibrosis supported by HRCT with or without surgical lung biopsy; FVC ≥ 50%; DLCO ≥ 30%
Clinical criteria (continuing):
Prior PBS-subsidised treatment with pirfenidone
Administrative authority:
Department of Human Services, Australia
Application requirement:
Completed authority prescription form and IPF Initial PBS authority application form with supporting diagnostic documentation
Geographical reference:
Hobart, TAS 7001, Australia
Year:
2023
Region / City:
Royal Devon & Exeter Hospital, Wonford, UK
Topic:
Healthcare, Physiotherapy
Document Type:
Job Description
Organization / Institution:
Royal Devon University Healthcare NHS Foundation Trust
Author:
N/A
Target Audience:
Healthcare professionals, physiotherapists
Period of Validity:
N/A
Approval Date:
N/A
Amendment Date:
N/A
Authors:
Petar Avramovski; Julijana Petrovska; Maja Avramovska
Affiliations:
St. Clement of Ohrid University – Bitola; Clinical Hospital – Bitola
Country:
North Macedonia
City:
Bitola
Medical Field:
Gastroenterology; Hepatology; Diagnostic Ultrasound
Type of Document:
Scientific research abstract
Study Design:
Observational clinical study
Study Population:
325 patients with non-alcoholic fatty liver disease (NAFLD)
Average Age of Participants:
54.2±8.5 years
Institutions Involved:
Department of Ultrasonography; Department of Gastroenterohepatology; Department of Gynecology and Obstetrics, Clinical Hospital – Bitola
Methods:
B-mode ultrasound imaging, echogenicity analysis software, laboratory tests for platelets, ALT and AST, calculation of FIB-4 score
Diagnostic Indicators Studied:
Hepatorenal Index (HRI); Fibrosis-4 (FIB-4) score
Conditions Examined:
Non-alcoholic fatty liver disease; nonalcoholic steatohepatitis; liver fibrosis; cirrhosis
Patient Group Classification:
Mild NAFLD; moderate NAFLD; severe NAFLD; significant fibrosis (≥F2); advanced fibrosis (≥F3); cirrhosis (F4)
Keywords:
hepatorenal index; FIB-4 score; NAFLD; liver fibrosis; cirrhosis; ultrasound diagnostics
Year:
2025
Organization:
Alder Hey Children’s NHS Foundation Trust
Department:
Department of Respiratory Medicine
Document type:
Patient information leaflet
Target audience:
Patients, parents and carers of children with cystic fibrosis
Topic:
Genetics of cystic fibrosis, carrier testing, reproductive options
Review date:
March 2025
Contact:
Tel: 0151 228 4811, www.alderhey.nhs.uk
Location:
Liverpool, United Kingdom
Year:
2023
Location:
Tarrytown, NY, USA
Subject:
Medical diagnostics, liver disease
Document type:
Press release
Organization:
Siemens Healthcare Diagnostics Inc.
Author:
Kimberly Nissen
Target audience:
Healthcare professionals, journalists
Regulatory status:
FDA Breakthrough Device Designation
Test:
Enhanced Liver Fibrosis (ELF™) Test
Biomarkers:
Hyaluronic acid (HA), Procollagen III amino-terminal peptide (PIIINP), Tissue inhibitor of metalloproteinase 1 (TIMP-1)
Clinical relevance:
Identification of advanced fibrosis and cirrhosis in NAFLD/NASH patients
Date issued:
July 18, 2023
Associated guidelines:
American Diabetes Association, American Association of Clinical Endocrinology, American Gastroenterological Association, American Association for the Study of Liver Diseases
Year:
Not specified
Region / Area:
Europe
Subject:
Post-authorisation safety and efficacy studies in cystic fibrosis registries
Document Type:
Application form
Organization:
European Cystic Fibrosis Society Patient Registry (ECFSPR)
Related Organization:
European Medicines Agency (EMA)
Applicant Type:
Marketing Authorisation Holder
Purpose:
Submission of requests for registry data for PASS / PAES studies
Required Attachments:
Study protocol; Statistical analysis plan
Submission Method:
Email submission to [email protected]
Key Sections:
Applicant details; Study information; Cohort definition; Statistical methods; Data requirements
Population Scope:
Patients included in the European Cystic Fibrosis Society Patient Registry
Historical Data Availability:
2008–2023
Fee Structure:
€5,000 handling; €25,000 review and feasibility assessment; €5,000 application modification
Governance Note:
Individual country applications outside ECFSPR governance may apply separate fees
Year:
2023
Region / City:
United Kingdom
Theme:
Health-related quality of life, Cystic fibrosis
Document Type:
Research Article
Author:
Rana Altabee, Siobhan B. Carr, Jaince Abbott, Rory Cameron, Daniel Office, Nicholas J. Simmonds, Jennifer A. Whitty, David Turner, Garry Barton
Target Audience:
Researchers, healthcare professionals, policy makers
Period of Study:
July 2020 – March 2021
Approval Date:
2023
Date of Changes:
None
Year:
2026
Location:
University of Cincinnati Hospital, 8 East Unit
Subject:
Cystic Fibrosis inpatient care and hospital protocols
Document Type:
Patient guidance / hospital procedure
Institution:
UC Hospital Pulmonary Consult Service
Author:
CF Nurse Practitioner Angela Oder
Target Audience:
CF patients and their families
Admission Requirements:
Direct or scheduled CF admissions
Infection Control:
Droplet & Contact isolation, personal protective equipment required
Dietary Guidelines:
High calorie diet (3000 cal/day), extended menu for CF patients
Medical Monitoring:
Vital signs every 8 hours, weight 2–4 times per week, glucose monitoring as needed
Therapy and Exercise:
4 respiratory therapy sessions/day, encouraged physical activity, home IV setup guidance upon discharge
Follow-up:
Appointment within 2 weeks post-discharge