№ lp_2_1_34597
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Review article summarizing mechanisms of programmed cell death in transplanted stem cells and discussing molecular pathways and strategies to improve cell survival in stem cell-based therapies.
Journal:
World Journal of Stem Cells
Manuscript Number:
64994
Manuscript Type:
Review
Authors:
Xi-Min Hu, Qi Zhang, Rui-Xin Zhou, Yan-Lin Wu, Zhi-Xin Li, Dan-Yi Zhang, Yi-Chao Yang, Rong-Hua Yang, Yong-Jun Hu, Kun Xiong
Funding:
National Natural Science Foundation of China, No. 81772134, No. 81971891, No. 81571939
Corresponding Author:
Kun Xiong, MD, PhD, [email protected]
Received:
February 26, 2021
Revised:
April 26, 2021
Accepted:
May 7, 2021
Published online:
May 26, 2021
Keywords:
Programmed cell death, Apoptosis, Autophagy, Stem cell, Therapeutic strategies
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Authors:
Vivianne J Goosens; Kenneth T Walker; Silvia M Aragon; Amritpal Singh; Vivek R Senthivel; Linda Dekker; Joaquin Caro-Astorga; Marianne L A Buat; Wenzhe Song; Koon-Yang Lee; Tom Ellis
Corresponding author:
Tom Ellis
Affiliation:
Imperial College Centre for Synthetic Biology, Imperial College London, London SW7 2AZ, UK
Note:
Affiliation
Department of Bioengineering, Imperial College London, London SW7 2AZ, UK
Institution:
Imperial College London
Field:
Synthetic biology; Engineered Living Materials; bacterial cellulose; modular cloning
Organisms:
Komagataeibacter rhaeticus; Komagataeibacter xylinus; Komagataeibacter hansenii; Escherichia coli
Methodology:
Golden Gate DNA assembly; Type IIS restriction enzymes; modular plasmid-based cloning
System described:
Komagataeibacter Tool Kit (KTK)
Application:
Multigene construct assembly and programmed protein secretion in cellulose-producing bacteria
Document type:
Scientific research article
Research focus:
Development and demonstration of a hierarchical modular cloning toolkit for cellulose-producing bacteria
Year:
2023
Region / City:
Australia
Subject:
Health / Oncology
Document Type:
Official Announcement
Organization:
Department of Health and Aged Care
Author:
Medical Services Advisory Committee (MSAC), Pharmaceutical Benefits Advisory Committee (PBAC)
Target Audience:
Healthcare providers, specialists
Effective Date:
1 September 2023
Approval Date:
10 August 2023
Changes Date:
1 September 2023
Clinical Category:
Pathology Services
Procedure Type:
Type C
Private Health Insurance Classification:
Support List (pathology)
MBS Item:
72814
PBS Listing:
pembrolizumab (Keytruda®)
Eligibility Criteria:
Advanced TNBC, PD-L1 Combined Positive Score (CPS) ≥10
Consulted Stakeholders:
Clinical experts, providers, consumer health representatives
Review and Monitoring:
Compliance audits
More Information:
www.mbsonline.gov.au
Description:
Official update on the inclusion of PD-L1 immunohistochemistry testing for advanced triple negative breast cancer (TNBC) patients under the Medicare Benefits Schedule (MBS) effective 1 September 2023, aligned with PBS listing for pembrolizumab.
Year:
2021
Event:
Expert meeting
Location:
Online
Organization:
UNESCO
Topic:
Intangible cultural heritage, listing mechanisms
Type of document:
Report / Meeting overview
Author:
Rieks Smeets
Target audience:
UNESCO member states, cultural heritage experts
Dates of event:
26–27 May 2021
Time:
13:00–16:00 (Paris time / UTC+2)
Historical period covered:
1960s–2008
Year:
2021
Region / city:
Online
Subject:
Intangible Cultural Heritage
Document type:
Background Paper
Organization:
UNESCO
Author:
UNESCO Secretariat
Target audience:
Experts, States Parties, practitioners in the field of intangible cultural heritage
Duration:
May 2021 – ongoing
Approval date:
Not provided
Amendment date:
Not provided
Year:
2020
Organization:
UNESCO
Session:
Eighth session of the General Assembly of the States Parties
Document type:
Report / Summary
Agenda item:
11 – Update on the reflection on the listing mechanisms of the Convention
Related decisions:
13.COM 6, 13.COM 10, 14.COM 14
Meeting location:
UNESCO Headquarters, Room I
Context:
Summary of progress and reflections on the implementation and evaluation of the listing mechanisms of the 2003 Convention, including impacts of COVID-19 and planned procedural revisions.
Year:
2017
Region / City:
China
Theme:
Budget Transparency
Document Type:
Policy Note
Organization:
World Bank
Author:
Carolina Luisa Vaira, Min Zhao
Target Audience:
Governments, policy makers, researchers, international organizations
Period of validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2023
Region / City:
Birmingham, Alabama
Topic:
Cancer Research, Grant Programs
Document Type:
Research Grant Information
Organization / Institution:
UAB (University of Alabama at Birmingham)
Author:
O’Neal Cancer Center
Target Audience:
UAB Faculty, Cancer Researchers
Period of Validity:
Ongoing
Approval Date:
Not specified
Modification Date:
Not specified
Contextual Description:
A guide for UAB faculty on applying for O’Neal Invests grants supporting cancer research in basic and population sciences.
Year:
2025
Region / City:
Arkansas, Missouri, Puerto Rico
Subject:
Soybean resistance, nematode resistance, genetic research, breeding, plant pathology
Document Type:
Final Report
Organization:
University of Arkansas, LSU, University of Missouri
Author:
Leandro Mozzoni, Tristan Watson, Travis Faske, Henry Nugyen, Pengyin Chen, Caio Vieira, Grover Shannon, Feng Lin
Target Audience:
Researchers, Plant Breeders, Agronomists
Period of Validity:
2022-2024
Approval Date:
July 22, 2025
Modification Date:
N/A
Year:
2023
Region / City:
Global
Field:
Natural Language Processing
Document Type:
Research Article
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Researchers, AI and NLP professionals
Period of Action:
Ongoing research
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2025
Region / City:
Rome
Subject:
Biodiversity, Environmental Policy
Document Type:
Decision
Organization:
Conference of the Parties to the Convention on Biological Diversity
Author:
Conference of the Parties
Target Audience:
Parties to the Convention on Biological Diversity, environmental policymakers
Period of Validity:
2025-2029
Approval Date:
27 February 2025
Amendment Date:
Not specified
Year:
2024
Region / city:
Nairobi
Theme:
Biodiversity
Document type:
Recommendation
Organ / institution:
Subsidiary Body on Implementation
Author:
Subsidiary Body on Implementation
Target audience:
Parties to the Convention on Biological Diversity, national authorities, environmental organizations
Period of validity:
2024-2026
Date of approval:
29 May 2024
Date of amendments:
N/A
Context:
A recommendation on the mechanisms for planning, monitoring, reporting, and review related to the implementation of the Kunming-Montreal Global Biodiversity Framework.
Year:
2020
Document type:
Written submission / advanced comments
Process:
Convention on Biological Diversity
Meeting:
Resumed session of the third meeting of the Subsidiary Body on Implementation
Reference documents:
CBD/SBI/3/11/Add.6; Annex B to CBD/SBI/3/CRP.5
Thematic focus:
Biodiversity governance; non-state actor commitments; reporting and review mechanisms
Author:
Liese Galvin
Affiliation:
Ministry of Foreign Affairs and Trade
Country:
New Zealand
Contributing entity type:
National government
Target framework:
Post-2020 Global Biodiversity Framework
Intended audience:
Convention on Biological Diversity bodies and Parties
Submission context:
Consultation on draft reporting template
Year:
2022
Region / City:
Montreal, Canada
Topic:
Biodiversity, Global Biodiversity Framework
Document Type:
Decision
Organization / Institution:
Conference of the Parties to the Convention on Biological Diversity
Author:
Conference of the Parties
Target Audience:
Parties to the Convention on Biological Diversity
Period of Validity:
Not specified
Approval Date:
December 2022
Date of Amendments:
None specified
Year:
2025
Region / City:
European Union, European Economic Area
Topic:
Payment Services, Financial Regulations, Verification Of Payee
Document Type:
Call for Interest
Organ / Institution:
European Payments Council (EPC)
Author:
European Payments Council
Target Audience:
Payment Service Providers (PSPs), Financial Institutions, Routing and Verification Mechanism Providers
Effective Period:
From 5 October 2025
Approval Date:
5 October 2025
Revision Date:
Not specified
Year:
2024
Region / city:
United States, California
Document type:
Speech / Written Submission
Organization:
United Nations
Author:
India Reed Bowers
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified