№ lp_1_2_45642
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Character count: 9721
File size: 75 KB
Detailed laboratory SOP outlining handling, preparation, dilution, storage, personal protective equipment, hazard identification, and emergency response measures for working with pertussis toxin, a protein-based exotoxin produced by Bordetella pertussis.
Year:
2026
Institution:
Duke University
Document Type:
Standard Operating Procedure (SOP)
Subject:
Pertussis toxin handling and safety
Author:
Not specified
Approval:
OESO SOP Approval Date provided
Intended Audience:
Laboratory personnel working with pertussis toxin
Hazard Classification:
Acute toxicity (oral, inhalation, dermal), eye irritation
Biosafety Level:
BSL-2 precautions recommended
Storage Conditions:
4°C in original container, secondary shatterproof container
Preparation Area:
Class II Biological Safety Cabinet (BSC) or Chemical Fume Hood (CFH)
Routes of Exposure:
Skin, inhalation, ingestion, injection
Emergency Procedures:
First aid and exposure response protocols specified
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2026
Region / City:
University of Washington
Theme:
Select Toxin Transfer, Due Diligence
Document Type:
Form
Organization / Institution:
University of Washington, Environmental Health & Safety
Author:
Not specified
Target Audience:
Researchers, Laboratory Personnel
Period of Validity:
Indefinite
Approval Date:
Not specified
Date of Amendments:
Not specified
Note:
Year
Topic:
Diphtheria Toxin Handling and Safety Protocol
Document Type:
Standard Operating Procedure
Target Audience:
Researchers, Laboratory Personnel
Year:
2023
Region / City:
Berkeley, CA
Topic:
Biosafety, Laboratory Procedures, Toxicology
Document Type:
Standard Operating Procedure (SOP)
Institution:
University of California, Berkeley
Author:
EH&S
Target Audience:
Researchers, Laboratory Personnel, Biosafety Officers
Period of Validity:
Ongoing
Approval Date:
2023
Amendment Date:
Not provided
Document Type:
Administrative form and procedural guideline
Subject:
Destruction of Select Agent Toxins
Regulatory Reference:
42 CFR 73.7(h); 42 CFR 73.21
Responsible Office:
Environmental Health and Safety (EH&S)
Related Authority:
U.S. Department of Health and Human Services
Applicable To:
Principal Investigators and laboratory personnel handling Select Agents or Toxins
Destruction Methods:
Chemical inactivation (sodium hypochlorite); autoclave heat treatment
Safety Requirements:
Laboratory hood or biological safety cabinet; specified personal protective equipment
Notification Requirement:
Written notice five business days prior to destruction
Witness Requirement:
EH&S staff member
Disposal Procedure:
Collection and disposal by Environmental Health and Safety
Contact Information:
Biosafety Office 928-523-7268
Year:
Not specified
Region / City:
Not specified
Subject:
Ophthalmology, Botulinum Toxin Therapy
Document Type:
Training Document
Organization:
Not specified
Author:
Not specified
Target Audience:
Orthoptists seeking training in botulinum toxin injections
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Organization:
STATDDS
Associated Organizations:
Merz; Allergan; Henry Schein; AAFE; BD
Products Mentioned:
Xeomin; Belotero Balance; Radiesse; Botox; Juvederm; Voluma; Comfortox Syringes; Bacteriostatic 0.9% Sodium Chloride; Alcohol Prep Pads
Document Type:
Product and Ordering Information Sheet
Industry:
Medical and Dental Aesthetics
Intended Audience:
Dental Professionals; Medical Professionals; Clinicians
Distribution Information:
Exclusive dental distribution of specified products by STATDDS
Contact Information:
800-693-9076; [email protected]
Note:
; 866-862-1211; 800-347-4500
Website:
STATDDS.com
Supplies Covered:
Syringes for reconstitution and injection; starter kits; bacteriostatic saline; ice packs; sterile needles
Packaging Details:
Individual sterile packaging; box quantities; vial quantities
Order References:
Henry Schein Order #890-8538; #104-6851; #987-8204; #987-1329
Year:
2023
Region / City:
USA
Topic:
Biosafety, Laboratory Protocols
Document Type:
Safety Manual
Organization / Institution:
University of Southern California
Author:
Unknown
Target Audience:
Laboratory Personnel
Period of Validity:
Ongoing
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
Not specified
Institution:
University of Florida
Department / Unit:
Environmental Health and Safety (EHS)
Document Type:
Standard Operating Procedure
Topic:
Laboratory biosafety and handling of pertussis toxin in animal research
Biological Agent:
Pertussis toxin
Source Organism:
Bordetella pertussis
Animal Model:
Rodents
Responsible Role:
Principal Investigator and laboratory staff
Related Policy:
Policy on Handling Animals Exposed to Biological Hazards
Required Approval:
Animal Use Protocol (AUP)
Engineering Controls:
Animal Transfer Station (ATS), Biosafety Cabinet (BSC), Chemical Fume Hood (CFH)
Personal Protective Equipment:
Lab attire, eye protection, long-sleeve gown or dedicated lab coat, single gloves
Clear Time After Administration:
72 hours
Waste Decontamination Methods:
Autoclaving at 121°C and 15 psi for 60 minutes or chemical inactivation with sodium hypochlorite
Emergency Contacts:
Environmental Health and Safety, University Police Department, Poison Control Center
Year:
2026
Location:
United States
Subject:
Veterinary Medicine, Nephrology
Document Type:
Research Article
Institutions:
The Ohio State University; University of Georgia; Oregon State University
Authors:
Rene Paschall, Jessica Quimby, Bianca Lourenço, Stacie Summers, Chad Schmiedt
Species Studied:
Domestic Cats
Sample Size:
14
CKD Stages:
IRIS Stage 2 and 3
Treatment:
Porus® One, oral adsorbent, 500 mg daily
Study Period:
112 days
Measurements:
Serum indoxyl sulfate, p-cresyl sulfate, Doppler blood pressure, biochemistry, urinalysis, urine protein:creatinine ratio
Study Design:
Prospective cross-sectional study
Year:
2023
Region / City:
[insert name of school district]
Theme:
Health and Safety
Document Type:
Letter
Organization / Institution:
[insert name of school district]
Author:
[insert name of school district]
Target Audience:
Parents, Guardians, Medical Providers
Period of Validity:
Ongoing
Approval Date:
[insert date]
Modification Date:
[insert date]
Year:
2024
Region / City:
Washington
Topic:
Pertussis Increase
Document Type:
Provider Alert
Agency / Organization:
Local Health Jurisdiction (LHJ)
Target Audience:
Healthcare providers
Effective Period:
2024-05-04
Date of Approval:
XXXXXX
Date of Updates:
Weekly
Contextual Description:
A public health alert informing healthcare providers in Washington about a significant increase in pertussis cases, including symptoms, diagnosis, testing, and preventive actions.
Year:
2025
Region / City:
England
Topic:
Immunisation
Document Type:
Patient Group Direction (PGD)
Organisation / Institution:
UK Health Security Agency (UKHSA)
Author:
Suki Hunjunt, Rebecca Cordery, Greta Hayward
Target Audience:
Healthcare practitioners
Period of Validity:
From 1 November 2025 to 1 November 2028
Approval Date:
24 September 2025
Revision Date:
23 September 2025
Year:
2024
Region / City:
United States
Topic:
Vaccination Protocol
Document Type:
Medical Protocol
Organization / Institution:
American Academy of Pediatrics (AAP), American Academy of Family Physicians (AAFP)
Author:
Prescriber
Target Audience:
Healthcare professionals
Period of validity:
Indefinite until rescinded
Approval Date:
March 26, 2024
Date of changes:
Not specified
Year:
2015
Region / city:
United Kingdom
Topic:
Immunisation
Document type:
Public Health Guideline
Organization / institution:
Public Health England
Author:
Elizabeth Graham, Mary Ramsay, David Green
Target audience:
Healthcare professionals, Registered Nurses, Paramedics
Period of validity:
From 15 December 2015 to 30 November 2017
Approval date:
15 December 2015
Amendment date:
N/A
Expiry date:
30 November 2017
Version:
v01.00
Review date:
1 June 2017
Reference number:
DTaP/IPV/Hib PGD
Note:
Change history
Version 1.00:
New PHE PGD template, 15 December 2015
Date:
[Date]
Region / City:
[Location of the childcare center/school]
Topic:
Health advisory
Document Type:
Health notification
Organization:
[Name of the school or childcare center]
Author:
[Not specified]
Target Audience:
Staff, Students, Parents/Legal Guardians
Period of Validity:
[Not specified]
Approval Date:
[Not specified]
Date of Changes:
[Not specified]
Year:
2023
Region / City:
USA
Topic:
Biosafety, Laboratory Protocols
Document Type:
Safety Manual
Organization / Institution:
University of Southern California
Author:
Unknown
Target Audience:
Laboratory Personnel
Period of Validity:
Ongoing
Approval Date:
Not specified
Date of Changes:
Not specified
Revision number:
SN11025 Rev. 10/18
Year:
2018
Region / City:
United States
Theme:
Laboratory Procedures
Document Type:
Procedure
Institution / Organization:
Meridian
Author:
Not specified
Target Audience:
Laboratory professionals
Period of Use:
Ongoing
Date Approved:
Not specified
Date of Revisions:
Not specified
Year:
2011
Region / city:
Washington State, USA
Topic:
Public health, vaccination
Document type:
Personal testimony / public health statement
Organization / institution:
Washington State Department of Health
Author:
Chelsey Charles
Official endorsement:
Mary Selecky, Washington State Secretary of Health
Target audience:
Teens and adults
Health concern:
Whooping cough (pertussis)
Call to action:
Get Tdap vaccination
Online resource:
doh.wa.gov
Personal impact:
Death of infant Kaliah
Year:
Not specified
Institution:
University of Florida
Department / Unit:
Environmental Health and Safety (EHS)
Document Type:
Standard Operating Procedure
Topic:
Laboratory biosafety and handling of pertussis toxin in animal research
Biological Agent:
Pertussis toxin
Source Organism:
Bordetella pertussis
Animal Model:
Rodents
Responsible Role:
Principal Investigator and laboratory staff
Related Policy:
Policy on Handling Animals Exposed to Biological Hazards
Required Approval:
Animal Use Protocol (AUP)
Engineering Controls:
Animal Transfer Station (ATS), Biosafety Cabinet (BSC), Chemical Fume Hood (CFH)
Personal Protective Equipment:
Lab attire, eye protection, long-sleeve gown or dedicated lab coat, single gloves
Clear Time After Administration:
72 hours
Waste Decontamination Methods:
Autoclaving at 121°C and 15 psi for 60 minutes or chemical inactivation with sodium hypochlorite
Emergency Contacts:
Environmental Health and Safety, University Police Department, Poison Control Center