№ files_lp_3_process_9_46971
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An official scientific position statement presenting evidence from human and animal studies on the metabolic conversion of alpha-linolenic acid to long chain n-3 polyunsaturated fatty acids and the comparative effects of ALA, EPA, and preformed DHA supplementation on blood and tissue DHA status.
Organization: International Society for the Study of Fatty Acids and Lipids (ISSFAL)
Document type: Official statement
Statement number: 5
Topic: Alpha-linolenic acid supplementation and conversion to n-3 long chain polyunsaturated fatty acids
Subject area: PUFA nutrition
Authors: J. Thomas Brenna; Norman Salem, Jr.; Andrew J. Sinclair; Stephen C. Cunnane
Affiliations: Division of Nutritional Sciences, Cornell University; Martek Biosciences, Inc.; Deakin University, School of Exercise & Nutrition Sciences; Research Center on Aging, Université de Sherbrooke
Approval body: ISSFAL Board of Directors
Geographical scope: International
Population focus: Humans and mammals, including infants and adults
Key substances: Alpha-linolenic acid (ALA); Eicosapentaenoic acid (EPA); Docosapentaenoic acid (DPA); Docosahexaenoic acid (DHA); Linoleic acid (LA)
Type of evidence: In vivo metabolic studies; tracer studies with stable isotopes; animal tissue compositional studies; human blood and breast milk analyses
Dietary context: Western diets rich in linoleic acid
Price: 8 / 10 USD
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