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The document explores the evolution of cancer cell metabolism, focusing on key metabolic reprogramming mechanisms, such as the Warburg effect and Crabtree effect, and their implications for cancer therapy.
Year:
2023
Region / City:
Kolkata, West Bengal
Subject:
Cancer Cell Metabolism
Document Type:
Review Article
Institution:
Guru Nanak Institute of Dental Sciences & Research
Author(s):
Dr. Abhishek Ghosh, Dr. Sanjeet Kumar Das, Prof Dr. Sk. Abdul Mahmud, Prof Dr. Mousumi Pal
Target Audience:
Researchers, Healthcare Professionals
Period of Application:
Ongoing
Date of Approval:
Not specified
Date of Changes:
Not specified
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
[year]
Region / City:
[location]
Subject:
Metabolism of active ingredient in plants
Document Type:
Research Report
Institution:
[institution]
Author:
[author]
Target Audience:
Regulatory bodies, researchers
Period of Validity:
[xx months]
Approval Date:
[date]
Date of Modifications:
[date]
Document ID:
MRID No.
Note:
PMRA No.
Report:
Report Citation
Guidelines:
EPA OCSPP Harmonized Test Guideline 860.1300 Nature of the Residue – Plants, Livestock (August 1996)
GLP Compliance:
[No or Significant] deviations from regulatory requirements were reported which would have an impact on the validity of the study. [If “Significant,” then explain below the deficiencies and their impact on the acceptability of the study]
Acceptability:
The study [is/is not] considered scientifically acceptable. [If not acceptable, then explain why below]
Evaluator:
[Name of regulatory person who reviewed the study]
Year:
2007
Region / city:
N/A
Subject:
Metabolism, distribution, and residue expression in livestock
Document type:
Research report
Organization / institution:
OECD, EPA
Author:
N/A
Target audience:
Researchers, regulatory bodies
Period of validity:
N/A
Approval date:
N/A
Amendment date:
N/A
Note:
Year
Context:
This document is a table listing key genes involved in carbon metabolism, as found in the KEGG database.
Date:
November 17, 2025
Type of document:
Cover letter
Manuscript title:
Effectiveness, Adherence, and Safety of Branded Wegovy™ vs. Compounded Semaglutide + Cyanocobalamin (CSC)
Article type:
Original Article
Journal:
The Journal of Obesity and Metabolism
Author:
Shanmugesh Raja, MS
Affiliation:
University of California, San Francisco
Study design:
Retrospective cohort study
Data source:
De-identified telemedicine cohort
Interventions studied:
FDA-approved semaglutide (Wegovy™) and compounded semaglutide + cyanocobalamin
Outcomes assessed:
Weight-loss magnitude and milestones, treatment adherence and persistence, adverse event reporting
Regulatory context:
FDA-approved semaglutide compared with compounded formulation
Conflict of interest disclosure:
Confirmed disclosed
Prior publication status:
Not previously published and not under consideration elsewhere
Document type:
Supplementary material
Study subject:
Effects of chronic blue and white LED lighting on gut microbiota and cholesterol metabolism in mice
Experimental duration:
44 weeks
Biological focus:
Gut microbiota composition and lipid metabolism
Key methods:
LEfSe analysis; LDA effect size; heatmap analysis; one-way ANOVA; correlation analysis; Venn diagram; BaseSpace (Illumina) identification
Main variables:
LED wavelength; irradiance level; serum cholesterol level; alpha diversity; bile acid biosynthesis
Organisms studied:
Mice; Lactobacillus spp.
Statistical threshold:
p value < 0.05
Figures included:
S1; S2; S3; S4; S5; S6
Analytical scope:
Taxonomic classification from kingdom to genus; signaling pathway analysis; correlation with serum cholesterol
Year:
2023
Region / City:
Rochester, Minnesota, USA; Padova, Italy
Topic:
Hepatic steatosis, glucagon, amino acid metabolism
Document Type:
Supplementary data for research article
Institution:
Mayo Clinic; University of Padova
Authors:
Hannah E. Christie, Sneha Mohan, Aoife M. Egan, Federica Boscolo, Chiara Dalla Man, Scott M. Thompson, Michael Jundt, Chad J. Fleming, James C. Andrews, Kent R. Bailey, Michael D. Jensen, K. Sree Nair, Adrian Vella
Target Audience:
Biomedical researchers, clinicians
Clinical Trial Registration:
NCT05500586
Conflict of Interest:
Adrian Vella consulted for Boehringer-Ingelheim, Neurotronics, and Rezolute; other authors declared no conflicts
Data Type:
Experimental measurements, statistical analyses, figures, and tables
Methods:
Splanchnic glucose and amino acid metabolism assays, linear regression analysis, clamp studies
Study Population:
Lean and obese subjects with varying hepatic Proton Density Fat Fraction (PDFF)
Supplementary Figures:
1–8
Supplementary Tables:
1–3
Correspondence:
Adrian Vella, Mayo Clinic, Rochester, MN, USA, [email protected]
Year:
2023
Region / City:
Ann Arbor, MI, USA
Topic:
Cancer Research, Glycolytic Metabolism, Cell Migration
Document Type:
Research Article
Organization:
University of Michigan
Authors:
Brock Humphries, Johanna M. Buschhaus, Yu-Chih Chen, Henry R. Haley, Tonela Qyli, Benjamin Chiang, Nathan Shen, Shrila Rajendran, Alyssa Cutter, Yu-Heng Cheng, Yu-Ting Chen, Jason Cong, Phillip C. Spinosa, Euisik Yoon, Kathryn E. Luker, Gary D. Luker
Target Audience:
Researchers, Medical Professionals, Oncology Specialists
Period of Action:
N/A
Date of Approval:
N/A
Date of Revisions:
N/A
Year:
2026
Region / City:
International
Subject:
Microbial C1 metabolism in soils
Document Type:
Conference session proposal
Organizers:
Jingjing Peng, Werner Liesack, Lei Cheng, Diana Z. Sousa
Proposed Speakers:
Diana Z. Sousa, Julia Vorholt, Marina G. Kalyuzhnaya, Colin Murrell, Kelly C. Wrighton, Yahai Lu, Shungui Zhou
Target Audience:
Microbiologists, soil biogeochemists, systems biologists, environmental modelers
Session Focus:
Microbial transformations of methane, CO2, CO, methanol, and formate in terrestrial ecosystems
Methods Highlighted:
Single-cell technologies, meta-omics, stable isotope tracing, machine learning
Environmental Context:
Soil microbial community responses to environmental changes
Detailed description:
Oral session proposal describing microbial mechanisms of C1 compound transformations in soils and their ecological impacts on greenhouse gas dynamics and carbon cycling.
Year:
February 2016
Region / city:
Not specified
Subject:
Metabolism and distribution of residues in plants and livestock
Document type:
Technical report
Organization:
Not specified
Author:
Not specified
Target audience:
Scientific researchers, agronomists
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
Note:
Year
Subject:
Metabolism, Energy, Cellular Respiration
Document Type:
Educational Guide
Author:
Mrs. Javon
Target Audience:
Students
Contextual description:
Educational material designed to guide students through the basic concepts of metabolism, including energy transfer and enzyme function.
Year:
2026
Region / City:
Shanghai, China; Neijiang, Sichuan, China; Adelaide, Australia
Topic:
Aquaculture, Lipid Metabolism, Myo-inositol
Document Type:
Research Article
Institution:
East China Normal University, Neijiang Normal University, Flinders University
Authors:
Xianyong Bu, Xiaodan Wang, Zhideng Lin, Chunling Wang, Lingyu Li, Shubin Liu, Qingchao Shi, Jian G. Qin, Liqiao Chen
Target Audience:
Researchers, Aquaculture Professionals, Environmental Health Specialists
Period of Study:
56 days
Date of Approval:
Not specified
Date of Modifications:
Not specified
Context:
This scientific article presents research on the effects of myo-inositol supplementation on the growth, antioxidant status, and lipid metabolism of Chinese mitten crabs in aquaculture.
Year:
Not specified
Institution:
Dr. V. S. Krishna Govt. Degree & PG College (A), Visakhapatnam
Program:
B.Sc. Botany
Semester:
III and IV
Type of Document:
Examination question paper
Subjects:
Plant Taxonomy and Embryology, Plant Physiology and Metabolism
Max Marks:
60 per semester
Duration:
3 hours per paper
Question Format:
Section A (Essay), Section B (Short Answer)
Topics Covered:
Botanical classification systems, vegetative and floral characters, embryo sac development, gametophyte and endosperm development, sap ascent, transpiration, enzyme mechanisms, Calvin cycle, lipid structure and functions, auxins, phytochrome, osmosis, nitrogen fixation, photophosphorylation, ATP synthase, gibberellins, photoperiodism, anaerobic respiration, photorespiration
Audience:
Undergraduate Botany students
Year:
2023
Region / City:
Tai’an, China
Topic:
Protein succinylation, hepatic metabolism, liver diseases
Document Type:
Research Article
Institution:
Shandong Agricultural University
Author:
Shuang Liu, Rui Li, Yawen Sun, Hai Lin, Haifang Li
Target Audience:
Researchers, healthcare professionals
Period of Action:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Subject:
Pharmacology
Field:
Medical education
Document type:
Multiple-choice question set with explanations
Topics:
Receptor pharmacology, CYP450 enzyme induction and inhibition, opioid metabolism, drug potency, half-life calculations, pharmacokinetics, phase I and phase II metabolism, volume of distribution, bioavailability
Drugs mentioned:
Verapamil, Sulphonylureas, Erythromycin, Fluconazole, Fentanyl, Codeine, Oxycodone, Hydrocodone, Aspirin, Digoxin, Atenolol, Diazepam, Phenytoin, Prilocaine, Lignocaine, Gentamycin
Biochemical systems:
Cytochrome P450 enzymes, CYP2D6, CYP3A4
Educational level:
Medical students / exam preparation
Content format:
Question and answer with explanatory notes
Language:
English
Year:
2016
Region / City:
Baoding, Hebei Province, China
Subject:
Plant biology, environmental toxicology, microbial interactions
Document Type:
Research manuscript
Institution:
College of Life Science, Hebei University
Author:
Zhao Zhao, Huijuan Shi, Cunqi Liu, Yueqiang Guan, Xianjiang Kang, Lingci Chen, Xiaofei Liang, Lei Jin
Target Audience:
Researchers in plant science and environmental microbiology
Species Studied:
Lemna aequinoctialis
Collection Site:
Dong Lake, Baoding City, Hebei Province, China
Cultivation Method:
Maintained in 50 L glass aquarium with environmental water, transferred to 1/10 Hoagland E+ solution; no genetic modifications
Publication:
Chemosphere
Date of Collection:
2016-06-24
RDSC Submission:
University of Jena
Year:
2024
Region / City:
Victoria
Topic:
Child Health Information Management
Document Type:
User Guide
Organization:
Victorian Maternal and Child Health (MCH)
Author:
Not specified
Target Audience:
MCH staff, clinicians
Period of validity:
Not specified
Approval Date:
Not specified
Date of changes:
Not specified
Year:
2023
Region / City:
Australia
Topic:
Taxation, Trusts, Tax Law
Document Type:
Letter
Organization:
Australian Taxation Office (ATO)
Author:
Australian Taxation Office (ATO)
Target Audience:
Tax professionals, trustees, private companies
Effective Period:
Since 1 July 2022
Approval Date:
September 2023
Date of Changes:
September 2023
Year:
2020
Region / City:
Liverpool
Theme:
Pharmacy Services
Document Type:
Meeting Agenda
Organization:
Liverpool LPC
Author:
Not specified
Target Audience:
LPC Members, Clinical Advisors, Pharmacy Staff
Period of Action:
October 2020
Date of Approval:
October 2020
Date of Changes:
Not specified
Note:
Year
Topic:
English grammar, Present Simple Tense
Document Type:
Educational material
Target Audience:
English language learners