№ files_lp_3_process_7_053627
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An academic review article examining the biological function of ERAP1 in antigen processing and its implications for immune regulation, autoimmunity, and cancer therapy.
Title:
ERAP1: A Potential Therapeutic Target for a Myriad of Diseases
Authors:
Emma Reeves; Yasmin Islam; Edward James
Author Affiliations:
Centre for Cancer Immunology, Faculty of Medicine, University Hospital Southampton, Southampton, UK; Institute for Life Sciences, University of Southampton, Southampton, UK
Corresponding Author:
Edward James
Correspondence Address:
Centre for Cancer Immunology, MP127, University Hospital Southampton, Tremona Road, Southampton SO16 6YD, UK
Contact Email:
[email protected]
Contact Telephone:
+44 2381205884
Contact Fax:
+44 2381205152
Keywords:
ERAP1; antigen processing and presentation; MHC I; CD8+ T cells; NK cells; cancer; autoimmunity
Subject Area:
Immunology; Cancer Immunology; Molecular Biology
Document Type:
Review Article
Institutions:
University Hospital Southampton; University of Southampton
Geographical Context:
Southampton, United Kingdom
Focus:
Role of ERAP1 in peptide trimming, immune regulation, polymorphisms, and therapeutic inhibition
Diseases Addressed:
Autoimmune diseases; Cancer; Melanoma; Colorectal carcinoma; Lymphoma
Molecular Targets:
ERAP1; ERAP2; MHC I; TAP; proteasome; immunoproteasome
Price: 8 / 10 USD
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Court:
Federal Court of Australia
Division:
General Division
Registry:
New South Wales District Registry
Judge:
Nicholas J
Date of judgment:
15 February 2013
Place of judgment:
Sydney
Case number:
NSD 643 of 2010
Citation:
[2013] FCA 65
Subject matter:
Patentability of isolated DNA and RNA
Legislation considered:
Patents Act 1990 (Cth); Statute of Monopolies s 6; Patents Act 1949 (UK); Intellectual Property Laws Amendment (Raising the Bar) Act 2012 (Cth)
Patent in suit:
Australian standard patent no 686004
Priority date of patent:
12 August 1994
Claims in issue:
Claims 1–3
Date of hearing:
20–24 February 2012
Counsel for Applicants:
Mr D Catterns QC with Dr P Cashman
Counsel for Respondents:
Mr D Shavin QC with Ms C Welsh
Outcome:
Application dismissed with costs; order for costs stayed for 21 days pending appeal
Year:
2025-26
Region / City:
Victoria
Theme:
Local Government Performance Reporting
Document Type:
Guide
Institution:
Local Government Victoria
Author:
Local Government Victoria
Target Audience:
Local government councils, public administrators
Period of Validity:
2025-26
Approval Date:
October 2022
Date of Amendments:
October 2022
Year:
2026
Region / City:
N/A
Topic:
Wireless LAN, MAC, Target links
Document Type:
Technical Paper
Organization / Institution:
IEEE
Author:
Chaoming Luo, Liuming Lu, Ning Gao, Huixuan Zhou, Liangxiao Xin
Target Audience:
IEEE 802.11 working group
Validity Period:
N/A
Approval Date:
Jan. 26, 2026
Modification Date:
N/A
Context:
Technical resolution proposal for CID changes in IEEE P802.11 standard related to target links preparation for wireless networks.
Year:
2019
Region / city:
Global
Topic:
Climate Change, Target Setting, Greenhouse Gas Emissions
Document Type:
Submission Form, Guidance
Organization / Institution:
Science Based Targets initiative (SBTi)
Author:
N/A
Target Audience:
Companies setting science-based targets for emissions reductions
Period of Validity:
April 2019 - October 2019
Approval Date:
N/A
Date of Changes:
N/A
Year:
2025
Region / City:
Singapore
Topic:
Target Validation, Drug Discovery
Document Type:
Call for Proposals
Organization:
Singapore Therapeutics Development Review (STDR)
Author:
N/A
Target Audience:
Researchers, Principal Investigators, Institutions
Period of Action:
2025
Approval Date:
N/A
Date of Last Changes:
N/A
Year:
2023
Region / City:
United States
Theme:
Education, Student Data Reporting
Document Type:
Template
Organization / Institution:
PED (Public Education Department)
Author:
Not specified
Target Audience:
Education professionals, school administrators
Validity Period:
Ongoing
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
[Year]
Region / City:
[Location]
Topic:
Concept of Operations, Solution Design, Service Integration
Document Type:
Conceptual Document
Agency / Organization:
[Name of Customer Agency]
Author:
[Author Name]
Target Audience:
[Stakeholders, Business Owners, Program Managers, Functional Leads]
Period of Validity:
[Start Date] – [End Date]
Approval Date:
[Approval Date]
Modification Date:
[Modification Date]
Year:
2014
Region / city:
Europe
Topic:
Gas market model, Energy regulation
Document type:
Report
Organization:
ACER (Agency for the Cooperation of Energy Regulators)
Author:
European energy regulators
Target audience:
Energy regulators, policymakers, energy market professionals
Period of validity:
2014–2025
Approval date:
October 2014
Date of changes:
N/A
Year:
2025
Region / city:
Canada
Topic:
Diet, physical activity, older adults
Document type:
Research supplementary material
Organization / institution:
NuAge Study
Author:
Didier Brassard, Nancy Presse, Stéphanie Chevalier
Target audience:
Researchers, health professionals, policymakers
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
2020
Document Type:
Submission Form and Guidance
Organization:
Science Based Targets initiative (SBTi)
Version:
4
Date Published:
April 2020
Scope:
Corporate target validation for greenhouse gas emissions
Contact Email:
[email protected]
Applicable Criteria:
SBTi Criteria V4.0 and V4.1
Submission Format:
Word Document
Target Audience:
Companies seeking SBTi target validation
Deadline for Publication:
Within six months of target approval
Validation Duration:
30 working days from receipt of signed terms
Year:
2025
Region / City:
Athens, Greece
Topic:
RCS, Vehicle, Scattering Points
Document Type:
Agenda Item
Organization / Institution:
3GPP TSG RAN WG1
Author:
Moderator (Xiaomi)
Target Audience:
Companies in the RAN1 #120 meeting
Period of Validity:
February 17th – 21st, 2025
Approval Date:
Not specified
Date of Changes:
Not specified
Context:
This document outlines the discussion and agreements made regarding the values and patterns of AB1 for monostatic RCS in vehicles, including the collection of parameter values from various companies and the possibility of extending the agreement to other target types.
Year:
2025
Region / City:
USA
Theme:
Easement Programs
Document Type:
Guidelines
Organization / Institution:
USDA NRCS
Author:
USDA NRCS
Target Audience:
State governments, program administrators
Period of Validity:
FY 2025
Approval Date:
September 2024
Modification Date:
N/A
Year:
2023
Region / City:
Unknown
Subject:
Behavioral analysis and intervention plan for individuals with challenging behaviors
Document Type:
Behavioral Report
Author:
Unknown
Target Audience:
Staff involved in the care or treatment of individuals with challenging behaviors
Period of Action:
Ongoing
Approval Date:
Unknown
Date of Changes:
Unknown
Note:
Year
Year:
2023
Region / City:
Not specified
Topic:
Project Agreement, Construction
Document Type:
Agreement
Author:
Not specified
Target Audience:
Clients, Contractors
Effective Period:
Not specified
Approval Date:
April 2023
Amendment Dates:
December 2023, April 2024
Note:
Contextual Description