№ files_lp_3_process_7_040699
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A guidance document intended for employers and health professionals, outlining biological monitoring of 4-methylpentan-2-one exposure in the workplace, including sample collection, transport, and interpretation of results.
Year: 2021
Region / City: United Kingdom
Topic: Workplace Exposure to Hazardous Substances
Document Type: Guidance
Organization / Institution: Health and Safety Executive (HSE)
Author: Health and Safety Executive
Target Audience: Employers, Health and Safety Officers
Period of Validity: Ongoing
Date of Approval: August 2021
Date of Amendments: Not specified
Biological Monitoring Guidance Value (BMGV): 20 μmol 4-methylpentan-2-one/L urine
CAS Number: 108-10-1
Alternative Names: Methyl isobutyl ketone (MIBK), Hexone
Note: Workplace Exposure Limits
8-hour TWA: 50 ppm, 208 mg/m3
15-minute STEL: 100 ppm, 416 mg/m3
Skin Notation: Yes
Sample Collection: Urine samples, 30mL, end of shift
Sample Transport: First-class post, within 48 hours
Analytical Method: Headspace-gas chromatography-mass spectrometry
Precision: <11% RSD within day, <14% RSD day-to-day
Sample Stability: 4 days at ambient temperature, >3 months at -20°C
Confounding Factors: None known
Unexposed Level: <1 µmol/L
Interpretation: Biological monitoring results indicate exposure control levels
Link to HSE Workplace Exposure Limits: http://www.hse.gov.uk/pubns/books/eh40.htm
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Program Overview of ATSDR Biomonitoring of Great Lakes Populations Program III (N=500 respondents)
Year: 2023
Region / City: Milwaukee Estuary Area of Concern, Wisconsin
Theme: Biomonitoring, Environmental Health
Document Type: Program Overview
Institution: Centers for Disease Control and Prevention
Target Audience: Licensed anglers, Burmese immigrants, and their descendants
Study Period: Not specified
Approval Date: Not specified
Modification Date: Not specified
Supplementary Material for Age-dependent Human Elimination Half-lives of Dioxin-like Polychlorinated Biphenyls Derived from Cross-Sectional Biomonitoring Data in the General Population
Year: 2018
Region / city: Beijing, China
Topic: Environmental Chemistry
Document Type: Research Supplementary Material
Organization: Peking University, Beihang University
Authors: Qun Gao, Yujie Ben, Zhaomin Dong, Jianying Hu
Target Audience: Researchers, Environmental Scientists
Period of validity: N/A
Approval Date: N/A
Date of amendments: N/A
Methodology: High-resolution Gas Chromatography-Mass Spectrometry (HRGC-MS)
Instrumentation: Agilent 6890 Series GC, JMS-800D Mass Spectrometer
Quality Control: US EPA Method 1613 standards
Note: Description
Topics: 4-Methylpentan-2-one MIBK Biomonitoring