№ files_lp_4_process_3_112008
File format: docx
Character count: 10996
File size: 1359 KB
Year:
2026
Study type:
Case-control genome-wide association study
Population:
Postoperative patients
Sample size:
140,164
Clinical variables:
Comorbidities, BMI, alcohol intake, smoking status, physical activity, operative category
Genetic variables:
SNPs, mapped genes, polygenic risk scores
Target condition:
Postoperative delirium
Data sources:
GWAS, PGS Catalog
Analysis:
Primary and sensitivity analyses, cardiothoracic and non-cardiothoracic cohorts
Key genes:
APOE, TOMM40, APOC1, APOC2, APOC4
Significant SNPs:
rs429358, rs157592, rs157582, rs11556505, rs10119, rs75627662
Effect sizes:
Odds ratios and confidence intervals for independent SNPs
Publication references:
DOI links for PGS scores
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2023
Region / City:
Boston, MA, USA; Palo Alto, CA, USA; Durham, NC, USA; Philadelphia, PA, USA; Cleveland, OH, USA
Topic:
COVID-19, Genetics, Epidemiology
Document Type:
Research Study Supplement
Organization / Institution:
VA Boston Healthcare System, Stanford University, Emory University, etc.
Author:
Jennifer E. Huffman, Yan V. Sun, Mehrdad Arjomandi, Themistocles L. Assimes, and others
Target Audience:
Researchers, Healthcare Professionals
Period of Activity:
Ongoing
Date of Approval:
Not specified
Date of Amendments:
Not specified
Year:
2017
Region / City:
Global
Topic:
Genome-Wide Association Study (GWAS) Analysis Plan
Document Type:
Scientific Plan
Author:
N/A
Target Audience:
Researchers in genomics and bioinformatics
Effective Period:
Ongoing
Approval Date:
June 2, 2017
Modification Date:
N/A
Year:
2023
Region / City:
N/A
Document Type:
Supplementary Material
Organization / Institution:
N/A
Author:
N/A
Effective Period:
N/A
Approval Date:
N/A
Date of Modifications:
N/A
Year:
N/A
Region / city:
N/A
Topic:
GWAS, paraquat resistance
Document type:
Research Supplement
Author:
N/A
Target audience:
Researchers in genetics and pharmacology
Period of validity:
N/A
Approval date:
N/A
Modification date:
N/A
Context:
This document provides data from a GWAS analysis identifying genetic variants associated with paraquat resistance in certain fungal strains.
Year:
2020
Field:
Veterinary Medicine; Canine Gastroenterology; Epidemiology
Document Type:
Scientific Research Article
Journal:
Journal of Veterinary Healthcare
Volume:
2
Issue:
1
Pages:
16–40
ISSN:
2575-1212
DOI:
10.14302/issn.2575-1212.jvhc-20-3225
Authors:
Fabrizio di Virgilio; Emanuela Rabaioli; Massimo Gualtieri; Luca Formaggini
Affiliations:
Clinique Vétérinaire VET24, Marcq-en-Baroeul, France; Clinica Veterinaria Lago Maggiore, Dormelletto, Italy; University of Milan, Faculty of Veterinary Medicine, Milan, Italy
Corresponding Author:
Fabrizio di Virgilio
Editor:
Mohammed Elmetwally
Study Location:
Northern Italy
Study Period:
2000–2018
Study Population:
215 dogs presented to a referral veterinary centre
Study Design:
Observational Case-Control Study
Subjects:
Dogs diagnosed with Gastric Dilatation-Volvulus and control dogs without GDV
Keywords:
Dog; Gastric Dilatation-Volvulus; Canine Gastroenteric; Gastroenterology; Stomach; Epidemiologic Factors
License:
Creative Commons Attribution License
Conflict of Interests:
None declared
Received:
February 19, 2020
Accepted:
March 06, 2020
Published:
March 09, 2020
Year:
2026
Region / City:
Baghdad, Iraq
Topic:
Type 2 Diabetes Mellitus, Periodontal Disease, Fungal Infections, Obesity, Inflammation
Document Type:
Research Article
Institution:
Gilgamesh University, College of Health and Medical Techniques
Authors:
Mohammed Mohaibes, Ammar Sabar, Mayada Al-khafaji
Target Audience:
Medical researchers, clinicians, and healthcare professionals
Study Design:
Case-control study
Sample Size:
150 participants (75 T2DM patients, 75 healthy controls)
Methods:
Oral swabs, blood analysis for CRP and ESR, fungal isolation via microscopy, culture, VITEK® 2 system
Period:
Not explicitly stated
Publication Status:
Preprint / Manuscript
Keywords:
Type 2 Diabetes Mellitus, Periodontal disease, Fungal infection, Obesity, Inflammation, CRP, ESR
Correspondence:
[email protected]
Year:
2025
Region / City:
Greater Manchester
Topic:
Delirium Awareness and Training
Document Type:
Working Document
Organization:
Dementia United, NHS Greater Manchester Integrated Care
Author:
Dementia United
Target Audience:
Health and social care staff, public, carers, family members
Action Period:
Ongoing
Approval Date:
April 2025
Review Date:
12 months from last review
Date of Changes:
N/A
Year:
2024
Region / city:
Greater Manchester
Topic:
Delirium in hospitals
Document type:
Toolkit
Organization / institution:
Dementia United
Author:
Dementia United
Target audience:
Healthcare professionals, carers, and family members
Period of validity:
Ongoing
Approval date:
January 2024
Date of last update:
Not specified
Keywords:
Delirium, hospitals, dementia, toolkit, healthcare
Contextual description:
A toolkit for healthcare professionals aimed at identifying, managing, and preventing delirium in hospital settings.
Year:
2024
Region / City:
Greater Manchester
Topic:
Delirium Management
Document Type:
Toolkit
Organization:
Dementia United
Author:
Dementia United
Target Audience:
Health and social care staff in the community and primary care
Effective Period:
January 2024
Approval Date:
January 2024
Last Updated:
N/A
Year:
2022
Region / city:
Europe
Topic:
Postoperative delirium
Document type:
Guideline update
Institution:
European Society of Anaesthesiology and Intensive Care Medicine (ESAIC)
Author:
Aldecoa C, Bettelli G, Bilotta F, Sanders RD, Spies CD et al.
Target audience:
Medical professionals, anaesthesiologists, intensive care specialists
Period of validity:
2022-ongoing
Approval date:
February 2022
Modification date:
Not specified
Contextual description:
This is an updated guideline on postoperative delirium for adult patients, covering risk factors, preventive measures, neuromonitoring, and treatment outcomes, based on the latest evidence and consensus.
Year:
2025
Region / City:
Canberra, Australia
Topic:
Cognitive impairment, delirium, dementia, healthcare procedures
Document Type:
Procedure
Organization / Institution:
Canberra Health Services
Author:
Canberra Health Services
Target Audience:
Clinical staff, healthcare providers
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2024
Region / city:
Greater Manchester
Topic:
Delirium management in community and primary care
Document type:
Toolkit
Organization:
Dementia United
Author:
Dementia United
Target audience:
Health and social care staff in community and primary care
Period of validity:
Ongoing
Approval date:
January 2024
Date of changes:
Not specified
Year:
2024
Region:
Greater Manchester
Country:
United Kingdom
Subject:
Delirium management in hospital settings
Document type:
Clinical guidance
Healthcare setting:
Acute hospital
Target audience:
Medical teams
Associated framework:
Greater Manchester Hospital Delirium Toolkit
Component:
TIME Bundle (Triggers, Investigations, Management, Engagement)
Population:
Adults aged 18 and over
Exclusions:
People under the influence of drugs and/or alcohol
Screening tools referenced:
4AT, NEWS2, Clinical Frailty Scale
Related organisations:
NHS England, British Geriatrics Society, Dementia United
Version:
2.0
Publication month:
January
Status:
Working document
Year:
2024
Region / city:
Greater Manchester
Topic:
Hospital delirium management
Document type:
Key document
Organization:
Dementia United
Author:
British Geriatric Society
Target audience:
Healthcare professionals
Effective period:
From January 2024
Approval date:
January 2024
Modification date:
Not specified
Year:
2024
Region / city:
Greater Manchester
Theme:
Delirium, healthcare
Document type:
Guideline
Organization:
Dementia United
Author:
Unspecified
Target audience:
Healthcare professionals
Period of validity:
Ongoing
Approval date:
January 2024
Date of changes:
Not specified
Year:
2024
Region / City:
Greater Manchester
Topic:
Delirium management in adults
Document type:
Clinical guidance / key document
Organization:
Dementia United, British Geriatric Society
Target audience:
Healthcare professionals managing adult patients with delirium
Version:
2.0
Date of publication:
January 2024
Patient age group:
Over 18 years
Notes:
For patients not under the influence of drugs or alcohol, clinical judgement required for red flags
Year:
2024
Region / city:
Greater Manchester
Topic:
Delirium management and engagement
Document type:
Guidance
Organization / institution:
Dementia United
Author:
Not specified
Target audience:
Healthcare professionals, family carers, and individuals supporting people with delirium
Effective period:
Ongoing
Approval date:
January 2024
Date of changes:
Not specified
Year:
2022-2024
Region / City:
Greater Manchester
Topic:
Delirium management and quality improvement
Document Type:
Report
Organization:
Dementia United (DU)
Author:
Helen Pratt, Professor Emma Vardy
Target Audience:
Healthcare professionals, stakeholders in dementia care
Period of validity:
June 2022 – June 2024
Approval Date:
June 2022
Date of Changes:
N/A
Year:
2021
Region / City:
N/A
Topic:
Delirium management
Document Type:
Clinical protocol
Organization / Institution:
Dementia United
Author:
N/A
Target Audience:
Healthcare practitioners working with patients diagnosed with delirium
Period of Validity:
N/A
Approval Date:
June 2021
Modification Date:
N/A
Year:
2024
Region / City:
Greater Manchester, UK
Topic:
Delirium management in hospital settings
Document type:
Guidance document
Organization / Institution:
Dementia United
Author:
Not specified
Target audience:
Medical teams
Period of validity:
From January 2024
Date of publication:
January 2024
Related documents:
Key Document 4b – non-medical teams guidance, Key Document 2 – 4AT screening, Key Document 3 – TIME Bundle
Context:
Clinical guidance source outlining assessment, identification, and ongoing management of delirium in hospitalized adults, including the use of 4AT, PINCH ME triggers, and medication reviews.