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Analysis of risks and management strategies for hyperkalemia during cardiopulmonary bypass, focusing on high potassium cardioplegia overdose and associated complications in pediatric and adult patients.
Year: 2026
Region / City: N/A
Topic: Hyperkalemia in cardiac surgery
Document type: FMEA (Failure Mode and Effects Analysis)
Organization / Institution: AmSECT Safety Committee
Author: Gary Grist RN CCP
Target audience: Medical professionals in cardiac surgery and perfusion
Period of validity: N/A
Approval date: N/A
Date of changes: N/A
Price: 8 / 10 USD
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FMEA for Monitoring and System Response: Guidelines and Updates from AIAG and VDA (2017)
Year: 2017
Organization: AIAG and VDA
Document type: Handbook
Topic: FMEA-MSR, Risk Analysis, Automotive Safety
Target audience: Engineers and quality management professionals in automotive industry
Scope: Monitoring and system response failures in products with hardware and software components
Standards referenced: ISO 26262, ASILs
Related methods: DFMEA, PFMEA, HARA
Example application: Tesla vehicle collision anticipation system
Purpose: Assess potential failures, monitoring capability, and system/user response
Should Insulin vs. no treatment be used for the treatment of acute hyperkalemia?
Year: 2015
Region / city: Global
Topic: Acute hyperkalemia treatment
Document type: Research review
Organization / institution: Not specified
Author: Not specified
Target audience: Healthcare professionals
Period of validity: Not specified
Date of approval: Not specified
Date of amendments: Not specified
Conflict of Interests: None
Clinical outcomes: Potassium levels, ECG findings
Main intervention: Intravenous calcium
Comparison: No intervention, other interventions, placebo
Setting: Adults
Background: The acute treatment of hyperkalemia was reviewed in 2015.
Assessment: Hyperkalemia is a common and life-threatening electrolyte imbalance.
Desirable effects: Moderate effect of pharmacological intervention in mitigating hyperkalemia.
Undesirable effects: Potential harm from calcium administration, especially in cardiac arrest patients.
Certainty of evidence: Low certainty, based on limited observational data.
Values: Primary outcome is ECG changes, with limited clinical relevant data.
Balance of effects: Suggests against routine calcium use in cardiac arrest (weak recommendation).
Resources required: Low cost of calcium.
Cost effectiveness: No evidence of cost-effectiveness studies.
Equity: No studies identified.
Acceptability: Calcium has been recommended in international guidelines, but the new suggestion may face resistance.
Feasibility: Feasible as a recommendation against routine use.
Context: This document reviews evidence on the use of intravenous calcium for acute hyperkalemia treatment and recommends against its routine use in patients with hyperkalemia-induced cardiac arrest.
Topics: CPB FMEA Hyperkalemia