№ files_lp_4_process_3_125363
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Supplemental source detailing experimental results on nanofilm-based constructs for tracheal cartilage regeneration, including in vitro biocompatibility and in vivo repair outcomes in a rabbit model.
Year: 2026
Region / City: Suzhou, Shanghai, Hangzhou, China
Field: Tissue Engineering, Regenerative Medicine
Document Type: Supplemental Information
Institution: Soochow University, Shanghai Jiao Tong University, Zhejiang Cancer Hospital
Authors: Wen Zhao, Fanglan Xu, Yumei Shen, Qifeng Ding, Yifei Wang, Leilei Liang, Wufei Dai, Yongbing Chen
Corresponding Authors: Leilei Liang, Wufei Dai, Yongbing Chen
Experimental Model: BMSCs-loaded nanofilms, rabbit tracheal defect model
Methods: Immunofluorescence staining, live/dead assay, CCK8 cell viability assay, tracheoscopy, MicroCT, HE staining
Treatment Groups: PLGA-GT, PLGA@ICA-GT, PLGA-GT@KGN, PLGA@ICA-GT@KGN
Observation Period: 2 weeks, 4 weeks, 8 weeks
Key Measurements: Cell viability, healing conditions (%), survival rate, histological evaluation
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