№ files_lp_4_process_3_133362
Supplementary tables and figures providing detailed methodology, baseline characteristics, adjusted hazard ratios, sensitivity analyses, and study design of a nationwide observational cohort study comparing non-vitamin K oral anticoagulants and vitamin K antagonists in patients with atrial fibrillation.
Year: 2016–2019
Region: Belgium
Topic: Clinical outcomes of oral anticoagulants
Document type: Supplementary material
Institution: InterMutualistic Agency (IMA); Belgian Ministry of Health
Author: Not specified
Population: Adult patients with atrial fibrillation receiving oral anticoagulants
Data sources: IMA database, Minimal Hospital Dataset (MHD)
Study design: Observational cohort study with IPTW and PSM analyses
Follow-up period: From initiation of oral anticoagulants to treatment switch, discontinuation, death, emigration, or January 1, 2019
Outcomes assessed: Mortality, thromboembolic events, major bleeding, treatment interactions
Covariates: Age, sex, comorbidities, medication history, clinical risk scores (CHA2DS2-VASc, HAS-BLED, Charlson Comorbidity Index)
Analytical methods: Inverse probability of treatment weighting (IPTW), propensity score matching (PSM), sensitivity analyses
Approval: Sectoral Committee of Social Security and Health, Section Health (IVC/KSZG/20/344)
Confidentiality: Pseudonymized data, encrypted storage
Price: 8 / 10 USD
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