№ files_lp_3_process_9_68000
Compilation of primary clinical research evaluating the effects of mesotherapy interventions on skin structure, hydration, elasticity, and histological markers.
Year: 2008–2016
Region: International multicenter studies
Topic: Mesotherapy, Hyaluronic Acid, Skin Aging
Document Type: Clinical research summary
Authors: Lacarrubba F, Tawfik HA, El-Domyati M, Taieb M, Savoia A, Baspeyras M, Sparavigna A, Tedeschi A, Abuaf OK
Study Design: Open-label pilot studies, randomized controlled trials, single-blind studies, intrapatient placebo-controlled trials
Sample Size: 6–64 patients per study
Intervention: Multiple micro-injections of hyaluronic acid, vitamins, antioxidants, PRP
Outcome Measures: Ultrasound echogenicity, skin elasticity, hydration, clinical photographs, histology, subjective and objective assessments
Level of Evidence: I–IV
Follow-up Duration: 3 weeks–6 months
Target Population: Adults with signs of photoaging or skin aging
Measured Parameters: Collagen types I, III, VII, elastin, tropoelastin, skin brightness, pigmentation, dermis thickness
Price: 8 / 10 USD
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