№ files_lp_4_process_3_132642
File format: docx
Character count: 17233
File size: 685 KB
Year:
2026
Type:
Supplementary material
Subjects:
Scutellarin, Osteoarthritis, Molecular targets, Genes
Databases:
GenCLiP3, SwissTargetPrediction, PharmMapper
Target count:
Over 600 genes
Research focus:
Drug-target interactions, Pathway analysis
Associated conditions:
Osteoarthritis
Experimental methods:
Computational prediction and literature curation
Data format:
Tables with gene lists
Context:
Supplementary source listing genes associated with Scutellarin and osteoarthritis, including predicted and literature-curated molecular targets for pharmacological and disease analysis.
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Policy Category:
INNF
Subject:
Hyalurons, Hyaluronic Acid (Durolane) or viscosupplementation
Indication:
Osteoarthritis
Commissioning Status:
Low priority for funding; not normally funded
Funding Process:
Individual Funding Request via Gloucestershire Clinical Commissioning Group
Date of Publication:
12 October 2015
Policy Review Date:
March 2025
Consultation Bodies:
MSK Clinical Programme Group; GHNHSFT; GP Membership (via CCG Live/What’s New This Week)
Consultation Period:
10 July – 7 August 2015
Patient Representative Involvement:
Yes (via CPG and ECCP membership)
Reviewing Bodies:
Effective Clinical Commissioning Policy Group; Integrated Governance and Quality Committee
Evidence Base:
NICE Clinical Guideline 177; peer-reviewed journal articles (2012)
Relevant Authority:
National Institute for Health and Clinical Excellence
Health System:
National Health Service
Commissioning Body Contact:
Gloucestershire Clinical Commissioning Group ([email protected]
Note:
)
Version History:
Version 1 (12.10.15); Version 2 (15.03.18, review date amended); Version 3 (10.03.22, review date amended to March 2025, no policy changes)
Journal:
Physical Therapy Reviews
Article Type:
Accepted manuscript (revised post-print)
DOI:
10.1080/10833196.2020.1763662
First Published Online:
13 May 2020
Authors:
M. Buhler; C. M. Chapple; S. Stebbings; J. Adams; D. Gwynne-Jones; G. D. Baxter
Corresponding Author:
Miranda Buhler
Affiliations:
Centre for Health, Activity and Rehabilitation Research, School of Physiotherapy, University of Otago, Dunedin, New Zealand; Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand; School of Health Sciences, University of Southampton, Southampton, UK; Department of Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Country:
New Zealand; United Kingdom
Study Registration:
Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12618001639213
Study Design:
Assessor-blinded, partially participant-blinded, parallel-group feasibility randomized controlled trial
Sample Size:
30 adults with thumb carpometacarpal osteoarthritis
Intervention:
Soft splint versus usual care control
Primary Outcomes:
Recruitment rate; retention rate; intervention acceptability; adverse events
Assessment Time Points:
Baseline; 4 weeks; 6 months
Keywords:
thumb; carpometacarpal; trapeziometacarpal; osteoarthritis; splinting; randomized controlled trial; feasibility study
Year:
2019
Region / City:
Zhejiang Province, China
Subject:
Osteoarthritis, Knee joint, Infrapatellar fat pad
Document Type:
Review Article
Author(s):
Li-Feng Jiang, Jing-Hua Fang, Li-Dong Wu
Target Audience:
Medical researchers, healthcare professionals in orthopedics
Period of Validity:
Ongoing
Approval Date:
June 26, 2019
Revision Date:
June 11, 2019
Note:
Year
Topic:
Osteoarthritis, Diagnosis, Treatment, Self-Management
Document Type:
Clinical Guidelines
Target Audience:
General Practitioners, Healthcare Providers
Year:
2022
Region / City:
Not specified
Topic:
Post-traumatic osteoarthritis, diabetes, osteoarthritis models
Document Type:
Journal Articles
Organization / Institution:
Various medical research institutions
Authors:
Rios-Arce ND, Murugesh DK, Hum NR, Sebastian A, Jbeily EH, Christiansen BA, Loots GG, Christiansen BA, Chan DD, van der Meulen MCH, Maerz T, Hsia AW, Jbeily EH, Mendez ME, Cunningham HC, Biris KK, Bang H, Lee CA, Loots GG
Target Audience:
Medical professionals, researchers in osteoarthritis and diabetes
Period of validity:
2021-2022
Approval Date:
Not specified
Date of revisions:
Not specified
Note:
Year
Year:
2026
Region / city:
Edinburgh, UK
Topic:
Knee osteoarthritis, gait analysis, motor control
Document type:
Research article
Institution:
Royal Infirmary of Edinburgh
Author:
Not specified
Study population:
50 adults with end-stage knee osteoarthritis
Gender distribution:
25 males, 25 females
Age range:
61–79 years
Methodology:
Uncontrolled manifold (UCM) analysis, motion capture, treadmill walking
Data collection period:
Not specified
Ethics approval:
REC reference 15/SS/0058
Keywords:
gait variability, uncontrolled manifold, knee, osteoarthritis, postural stability
Title:
Information Sheet No. 15: Osteoarthritis
Subject:
Osteoarthritis and foot joint involvement
Document type:
Information sheet
Medical field:
Rheumatology; Podiatry
Health condition:
Osteoarthritis
Affected body areas:
Knees; hips; hands; feet; big toe joints
Organization referenced:
Arthritis Research Campaign
Estimated prevalence:
8 million people in Britain
Primary audience:
Patients and individuals concerned about joint pain
Topics covered:
Symptoms; causes; risk factors; self-care; footwear; exercise; podiatric care; medical treatment; surgery
Healthcare professionals mentioned:
General practitioner; podiatrist; rheumatologist; physiotherapist; occupational therapist; podiatric surgeon
Preventive measures:
Appropriate footwear; regular exercise; pressure redistribution
Treatment options described:
Painkillers; steroids; topical creams; orthoses; footwear modification; strapping and padding; surgical procedures
Related conditions:
Hallux rigidus; hallux valgus; bunions
Geographic reference:
United Kingdom
Information source mentioned:
Arthritis Research Campaign website
Note:
Year Group
Year:
N/A
Region / City:
N/A
Theme:
Occupational Safety and Health
Document Type:
Procedure
Organization / Institution:
N/A
Author:
N/A
Target Audience:
N/A
Period of Validity:
N/A
Approval Date:
DD.MM.YYYY
Date of Changes:
N/A
Note:
Year
Region / City:
Georgia
Theme:
Land Degradation Neutrality, Pastureland Management, Sustainability
Document Type:
Project Identification Form
Organization / Institution:
GEF, MEPA
Target Audience:
Stakeholders in environmental management, local communities, governmental bodies
Period of Action:
36 months
Context:
This document outlines a project proposal aimed at achieving land degradation neutrality in Georgia through the restoration and sustainable management of degraded pasturelands, as part of the GEF initiative.
Effective Date:
January 1, 2025
Year:
2025
Region / City:
-
Subject:
Fire protection, ignition and damage criteria for electrical cables and other targets
Document Type:
Technical manual
Agency/Organization:
NRC (Nuclear Regulatory Commission)
Author:
-
Target Audience:
Nuclear safety professionals, fire protection engineers
Duration:
-
Approval Date:
-
Amendment Date:
-
Year:
2024/2025
Note:
Region / City
Subject:
Education
Document type:
Action Plan
Target Audience:
Educational staff, leaders, governors
Period of Validity:
2024-2025
Year:
2023
Region / City:
Greenbelt, MD
Theme:
Remote Sensing, Calibration Targets, Earth Science
Document Type:
Research Paper
Institution:
NASA Goddard Space Flight Center
Author:
Georgi Georgiev, Joel McCorkel, Julia Barsi, Jessica Patel, Guangjun Gao, Elena Georgieva
Target Audience:
Researchers, Engineers, NASA Calibration Teams
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Amendments:
Not specified
Year:
2026
Region / City:
Global
Topic:
Antimalarial drug discovery, Plasmodium falciparum
Document Type:
Research Paper
Organization / Institution:
Not specified
Author:
Abigail Obuobi
Target Audience:
Researchers, Pharmaceutical Developers
Period of validity:
N/A
Date of approval:
N/A
Date of changes:
N/A
Year:
2025
Country:
South Africa
Institution:
Ministry of Employment and Labour
Parliamentary Body:
National Council of Provinces
Question Number:
1318 [CW1524E]
Questioner:
Mr P J Swart (Western Cape: DA)
Legislation Referenced:
Employment Equity Amendment Act of 2022
Regulations Referenced:
EE Regulations commenced on 15 April 2025
Related Act:
Employment Equity Act, 1998 (as amended)
Constitutional Reference:
Constitution of the Republic of South Africa, Sections 9 and 23
Subject:
Sectoral numerical employment equity targets and constitutionality
Document Type:
Parliamentary written reply
Format:
Official governmental correspondence
Year:
2025
Region / city:
Australian Capital Territory
Topic:
Housing targets, Urban renewal
Document type:
Government instrument
Organization / institution:
City Renewal Authority and Suburban Land Agency
Author:
Yvette Berry MLA
Target audience:
Public sector, urban planners, housing developers
Effective period:
2025-2026
Approval date:
26/09/2025
Amendment date:
Not specified
Year:
7th Grade
Note:
Region / City
Topic:
Poetry, Sonnet Analysis
Document Type:
Lesson Plan
Target Audience:
7th Grade Students
Language:
English
Assessment Type:
In-Class Assessment
Project Type:
Poetry Presentation
Year:
2024
Region / City:
Greenmeadows
Subject:
Education
Document Type:
Statement
Institution:
Greenmeadows School
Author:
Not specified
Target Audience:
School administrators, educators, parents, and community members
Period of validity:
2024
Approval Date:
Not specified
Date of Changes:
Not specified
Note:
Contextual Description