№ lp_2_3_38422
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Detailed patient characteristics, genomic breakpoints, assay parameters, and MRD quantification results are compiled from clinical samples and experimental analyses in this supplemental source.
Year: 2000–2022
Study Type: Clinical research
Patient Population: ABL-class leukemia patients
Sample Type: Bone marrow and blood DNA
Assay Methods: RNA sequencing, targeted locus amplification (TLA), genomic capture high throughput sequencing (gc-HTS), Fusion Detection by Gene Enrichment (FUDGE), long-range PCR, Sanger sequencing
Quantitative Assay: MRD Q-PCR based on genomic breakpoints and IG/TR targets
Institution: Princess Máxima Centrum, Netherlands; USEQ sequencing facility, Utrecht, Netherlands; Macrogen Europe
Ethics: Written informed consent obtained according to the Declaration of Helsinki
Data Tables: Supplemental Digital Tables 1–3
Figures: Supplemental Digital Figures 1–2
Reference Protocols: EuroMRD guidelines
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